Zobrazeno 1 - 10
of 428
pro vyhledávání: '"PierFranco Spano"'
Autor:
Ginetta Collo, Laura Cavalleri, Federica Bono, Cristina Mora, Stefania Fedele, Roberto William Invernizzi, Massimo Gennarelli, Giovanna Piovani, Tilo Kunath, Mark J. Millan, Emilio Merlo Pich, PierFranco Spano
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
The antiparkinsonian ropinirole and pramipexole are D3 receptor- (D3R-) preferring dopaminergic (DA) agonists used as adjunctive therapeutics for the treatment resistant depression (TRD). While the exact antidepressant mechanism of action remains unc
Externí odkaz:
https://doaj.org/article/06206ad6229e4f14aafa3ea2842b7478
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Parkinson’s disease (PD), the most common neurodegenerative disorder, is characterized by abnormal accumulation of α-synuclein aggregates known as Lewy bodies (LB) and loss of nigrostriatal dopaminergic neurons. Recent neuroimaging studies suggest
Externí odkaz:
https://doaj.org/article/3ab5b91e08dd49acbde49ba49dccf6d2
Autor:
Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson’s disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriata
Externí odkaz:
https://doaj.org/article/bbf70845c07c4a82832b2f4a0f7ab625
Autor:
Annamaria Lanzillotta, Giuseppe Pignataro, Caterina Branca, Ornella Cuomo, Ilenia Sarnico, Marina Benarese, Lucio Annunziato, PierFranco Spano, Marina Pizzi
Publikováno v:
Neurobiology of Disease, Vol 49, Iss , Pp 177-189 (2013)
Nuclear factor-kappaB (NF-κB) p50/RelA is a key molecule with a dual effect in the progression of ischemic stroke. In harmful ischemia, but not in preconditioning insult, neurotoxic activation of p50/RelA is characterized by RelA-specific acetylatio
Externí odkaz:
https://doaj.org/article/a51f7c5096a847f2aa7ba4dffb73f3c5
Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First?
Autor:
Michela Zaltieri, Francesca Longhena, Marina Pizzi, Cristina Missale, PierFranco Spano, Arianna Bellucci
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
Parkinson’s disease (PD) is the most common neurodegenerative movement disorder. Its characteristic neuropathological features encompass the loss of dopaminergic neurons of the nigrostriatal system and the presence of Lewy bodies and Lewy neurites.
Externí odkaz:
https://doaj.org/article/04879618118e49ec9018b84610643b5e
Autor:
Michele Ettorre, Erika Lorenzetto, Claudia Laperchia, Cristina Baiguera, Caterina Branca, Manuela Benarese, PierFranco Spano, Marina Pizzi, Mario Buffelli
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31451 (2012)
BACKGROUND: The functioning of the nervous system depends upon the specificity of its synaptic contacts. The mechanisms triggering the expression of the appropriate receptors on postsynaptic membrane and the role of the presynaptic partner in the dif
Externí odkaz:
https://doaj.org/article/7379bce22e9d487da6b191523fd4d0e6
Autor:
Michele Ettorre, Erika Lorenzetto, Claudia Laperchia, Cristina Baiguera, Caterina Branca, Manuela Benarese, PierFranco Spano, Marina Pizzi, Mario Buffelli
Publikováno v:
PLoS ONE, Vol 7, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/c6f26f10611849f1be27597c711f42e1
Autor:
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia Spillantini, Cristina Missale, PierFranco Spano
Publikováno v:
PLoS ONE, Vol 7, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/445395d893f744a58cc1694d213c3fe0
Autor:
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia Spillantini, Cristina Missale, Pierfranco Spano
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27959 (2011)
Alpha-synuclein, the major component of Lewy bodies, is thought to play a central role in the onset of synaptic dysfunctions in Parkinson's disease (PD). In particular, α-synuclein may affect dopaminergic neuron function as it interacts with a key p
Externí odkaz:
https://doaj.org/article/5da87a134a2b4ad690d2f6d216a0f758
Autor:
Francesca Longhena, Anders Björklund, Cristina Missale, Tatiana Varanita, Luigi Bubacco, Arianna Bellucci, Gaia Faustini, PierFranco Spano, Marina Pizzi, Fabio Benfenati
Publikováno v:
Acta Neuropathologica. 136:621-639
Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by the progressive loss of nigral dopamine neurons. The deposition of fibrillary aggregated α-synuclein in Lewy bodies (LB), that is considered to play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8307d9cfcb86c370c53443aba9dac67f
https://doi.org/10.1007/s00401-018-1892-1
https://doi.org/10.1007/s00401-018-1892-1