Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Pier Paolo Giovannini"'
Autor:
Lindomar Alberto Lerin, Giada Botti, Alessandro Dalpiaz, Anna Bianchi, Luca Ferraro, Chaimae Chaibi, Federico Zappaterra, Domenico Meola, Pier Paolo Giovannini, Barbara Pavan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6263 (2024)
Ferulic acid (Fer) and geraniol (Ger) are natural compounds whose antioxidant and anti-inflammatory activity confer beneficial properties, such as antibacterial, anticancer, and neuroprotective effects. However, the short half-lives of these compound
Externí odkaz:
https://doaj.org/article/29292328082746ebb1cc97b9bc3e2108
Autor:
Federico Zappaterra, Domenico Meola, Francesco Presini, Simona Aprile, Valentina Venturi, Chiara Nosengo, Chiara De Luca, Martina Catani, Lindomar Alberto Lerin, Pier Paolo Giovannini
Publikováno v:
Current Research in Biotechnology, Vol 8, Iss , Pp 100231- (2024)
Naturally occurring cinnamic acid derivatives are a broad family of aromatic carboxylic acids with bioactive properties. Among the cinnamic acid derivatives, for instance, are ferulic acid and caffeic acid, which have been widely studied for their an
Externí odkaz:
https://doaj.org/article/b851348c54e346ed824db89da555ff69
Autor:
Valentina Venturi, Elena Marchesi, Daniela Perrone, Valentina Costa, Martina Catani, Simona Aprile, Lindomar Alberto Lerin, Federico Zappaterra, Pier Paolo Giovannini, Lorenzo Preti
Publikováno v:
Molecules, Vol 29, Iss 6, p 1305 (2024)
Ursodeoxycholic acid (UDCA) and acetoacetate are natural compounds present in the human intestine and blood, respectively. A number of studies highlighted that besides their well-known primary biological roles, both compounds possess the ability to i
Externí odkaz:
https://doaj.org/article/eca37f5df30646c3b896a276b4314dc9
Autor:
Federico Zappaterra, Francesco Presini, Valentina Venturi, Lindomar Alberto Lerin, Pier Paolo Giovannini, Stefania Costa
Publikováno v:
Applied Sciences, Vol 13, Iss 17, p 9852 (2023)
Due to its effectiveness, ibuprofen is one of the most popular anti-inflammatory drugs worldwide. However, the poor water solubility of this active ingredient severely limits its spectrum of pharmaceutical formulations (and often results in severe ad
Externí odkaz:
https://doaj.org/article/2c6675edfcc34a93a771ade0e45185be
Autor:
Valentina Venturi, Lindomar Alberto Lerin, Francesco Presini, Pier Paolo Giovannini, Martina Catani, Alessandro Buratti, Nicola Marchetti, Latha Nagamani Dilliraj, Simona Aprile
Publikováno v:
Catalysts, Vol 13, Iss 4, p 691 (2023)
Molecular hybrids obtained by connecting two or more bioactive molecules through a metabolizable linker are used as multi-target drugs for the therapy of multifactorial diseases. Ascorbic acid, as well as the ketone bodies acetoacetate and (R)-3-hydr
Externí odkaz:
https://doaj.org/article/7169c7fdc62d46a3b1c5bf1bd0c79194
Autor:
Francesco Presini, Graziano Di Carmine, Pier Paolo Giovannini, Virginia Cristofori, Lindomar Alberto Lerin, Olga Bortolini, Claudio Trapella, Anna Fantinati
Publikováno v:
Catalysts, Vol 11, Iss 12, p 1440 (2021)
2,3-dihydroxy-2-methylbutyric acid, also known as 2,3-dimethylglyceric acid, constitutes the acyl and/or the alcoholic moiety of many bioactive natural esters. Herein, we describe a chemoenzymatic methodology which gives access to all the four possib
Externí odkaz:
https://doaj.org/article/4f3fa93cc7ed4efcb10badab723d643a
Autor:
Anna Zaghi, Daniele Ragno, Graziano Di Carmine, Carmela De Risi, Olga Bortolini, Pier Paolo Giovannini, Giancarlo Fantin, Alessandro Massi
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2719-2730 (2016)
A convenient heterogeneous continuous-flow procedure for the polarity reversal of aromatic α-diketones is presented. Propaedeutic batch experiments have been initially performed to select the optimal supported base capable to initiate the two electr
Externí odkaz:
https://doaj.org/article/f66dfc9fed3146e3acc5c8206120459b
Publikováno v:
International Journal of Analytical Chemistry, Vol 2019 (2019)
The retention mechanism of four major carotenoids, two xanthophylls (i.e., lutein and zeaxanthin) and two carotenes (i.e., lycopene and β-carotene), was investigated in reversed-phase liquid chromatography with the aim of thermodynamic analysis. The
Externí odkaz:
https://doaj.org/article/2dcda46c98574614b16d72a2a5f29e8f
Autor:
Ferdinando Zaccone, Valentina Venturi, Pier Paolo Giovannini, Claudio Trapella, Marco Narducci, Hugues Fournier, Anna Fantinati
Publikováno v:
Catalysts, Vol 11, Iss 1, p 140 (2021)
Recent studies have highlighted the therapeutic and ergogenic potential of the ketone body ester, (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate. In the present work, the enzymatic synthesis of this biological active compound is reported. The (R)-3-hydroxy
Externí odkaz:
https://doaj.org/article/69fa1dc1b8fb40048e3c36aeb6da9ea6
Autor:
Anna Fantinati, Lindomar Alberto Lerin, Olga Bortolini, Francesco Presini, Claudio Trapella, Pier Paolo Giovannini, Graziano Di Carmine, Virginia Cristofori
Publikováno v:
Catalysts; Volume 11; Issue 12; Pages: 1440
Catalysts, Vol 11, Iss 1440, p 1440 (2021)
Catalysts, Vol 11, Iss 1440, p 1440 (2021)
2,3-dihydroxy-2-methylbutyric acid, also known as 2,3-dimethylglyceric acid, constitutes the acyl and/or the alcoholic moiety of many bioactive natural esters. Herein, we describe a chemoenzymatic methodology which gives access to all the four possib