Zobrazeno 1 - 10
of 614
pro vyhledávání: '"Pier Paolo, Piccaluga"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 5, Pp 1027-1055 (2024)
The bone marrow microenvironment (BMM) has highly specialized anatomical characteristics that provide a sanctuary place for hematopoietic stem cells (HSCs) that allow appropriate proliferation, maintenance, and self-renewal capacity. Several cell typ
Externí odkaz:
https://doaj.org/article/2f76eee370ce41b982c7bc0671e23a90
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/af905b025a564384a6ec3a254614a46c
Publikováno v:
Hemato, Vol 4, Iss 1, Pp 68-75 (2023)
In the past twenty years, tyrosine kinase inhibitors (TKIs) have substantially changed the therapeutic landscape and the clinical outcome of several cancers, including Philadelphia-chromosome positive chronic myeloid leukemia and acute lymphoblastic
Externí odkaz:
https://doaj.org/article/52218340b84248a392fa75b56483d208
Publikováno v:
Hemato, Vol 4, Iss 1, Pp 42-55 (2023)
The prognosis of adult acute lymphoblastic leukemia (ALL) is variable but more often dismal. Indeed, its clinical management is challenging, current therapies inducing complete remission in 65–90% of cases, but only 30–40% of patients being cured
Externí odkaz:
https://doaj.org/article/d3019bc2832b46189845ecba1a59e474
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/6457107f2e8a4b819ab45cced047c090
Autor:
Riccardo Cecchetto, Emil Tonon, Nicoletta Medaina, Giona Turri, Erica Diani, Pier Paolo Piccaluga, Angela Salomoni, Michela Conti, Evelina Tacconelli, Anna Lagni, Virginia Lotti, Mosé Favarato, Davide Gibellini
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2378 (2023)
Next-generation sequencing (NGS) from SARS-CoV-2-positive swabs collected during the last months of 2022 revealed a large deletion spanning ORF7b and ORF8 (426 nt) in six patients infected with the BA.5.1 Omicron variant. This extensive genome loss r
Externí odkaz:
https://doaj.org/article/22a40d61f03d4bd5850d0d880085740a
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Nodal peripheral T-cell lymphomas (PTCL) are uncommon and heterogeneous tumors characterized by a dismal prognosis. Targeted therapy has been proposed. However, reliable targets are mostly represented by a few surface antigens (e.g., CD52 and CD30),
Externí odkaz:
https://doaj.org/article/abc6bc47a97e4c3a91012718def4006b
Autor:
Mercy Gatua, Mohsen Navari, Matilda Ong’ondi, Noel Onyango, Serah Kaggia, Emily Rogena, Giuseppe Visani, Nicholas A. Abinya, Pier Paolo Piccaluga
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Acute myeloid leukemia (AML) is an infrequent disease, and it is associated with high morbidity and mortality. It harbors a unique configuration of cytogenetic abnormalities and molecular mutations that can be detected using microscopic and molecular
Externí odkaz:
https://doaj.org/article/00ccaf2674ab45c1939ae8784b774606
Autor:
Massimo Granai, Lucia Mundo, Ayse U. Akarca, Maria Chiara Siciliano, Hasan Rizvi, Virginia Mancini, Noel Onyango, Joshua Nyagol, Nicholas Othieno Abinya, Ibrahim Maha, Sandra Margielewska, Wenbin Wi, Michele Bibas, Pier Paolo Piccaluga, Leticia Quintanilla-Martinez, Falko Fend, Stefano Lazzi, Lorenzo Leoncini, Teresa Marafioti
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background The Tumor Microenviroment (TME) is a complex milieu that is increasingly recognized as a key factor in multiple stages of disease progression and responses to therapy as well as escape from immune surveillance. However, the precis
Externí odkaz:
https://doaj.org/article/4a1bf0e8a3fb480eacc9be50f2a8c94b
Autor:
Erica Diani, Pier Paolo Piccaluga, Virginia Lotti, Andrea Di Clemente, Marco Ligozzi, Pasquale De Nardo, Lorenza Lambertenghi, Francesca Pizzolo, Simonetta Friso, Giuliana Lo Cascio, Alice Vianello, Giacomo Marchi, Ercole Concia, Davide Gibellini
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08192- (2021)
The dramatic impact of SARS-CoV-2 infection on the worldwide public health has elicited the rapid assessment of molecular and serological diagnostic methods. Notwithstanding the diagnosis of SARS-CoV-2 infection is based on molecular biology approach
Externí odkaz:
https://doaj.org/article/28c551a20ee34541a5b63b001977cd67