Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pier Francesca Porceddu"'
Autor:
Carlo Brighi, Federico Salaris, Alessandro Soloperto, Federica Cordella, Silvia Ghirga, Valeria de Turris, Maria Rosito, Pier Francesca Porceddu, Chiara D’Antoni, Angelo Reggiani, Alessandro Rosa, Silvia Di Angelantonio
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-22 (2021)
Abstract Fragile X syndrome (FXS) is a neurodevelopmental disorder, characterized by intellectual disability and sensory deficits, caused by epigenetic silencing of the FMR1 gene and subsequent loss of its protein product, fragile X mental retardatio
Externí odkaz:
https://doaj.org/article/0351c777a3714b9bbe0d47abd6b491b8
Autor:
Valeria Capurro, Massimiliano Lanfranco, Maria Summa, Pier Francesca Porceddu, Mariasole Ciampoli, Natasha Margaroli, Lucia Durando, Beatrice Garrone, Rosella Ombrato, Serena Tongiani, Angelo Reggiani
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 128, Iss , Pp 110249- (2020)
Glycogen synthase kinase 3β (GSK-3β) is a serine/threonine protein kinase mediating phosphorylation on serine and threonine amino acid residues of several target molecules. The enzyme is involved in the regulation of many cellular processes and abe
Externí odkaz:
https://doaj.org/article/3d54e17ad2224a2589422a5969c79f1e
Autor:
Giulia Costa, Annalisa Pinna, Pier Francesca Porceddu, Maria Antonietta Casu, Anna Di Maio, Francesco Napolitano, Alessandro Usiello, Micaela Morelli
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
We have recently shown that male Rhes knockout (KO) mice develop a mild form of spontaneous Parkinson’s disease (PD)-like phenotype, characterized by motor impairment and a decrease in nigrostriatal dopamine (DA) neurons. Experimental evidence has
Externí odkaz:
https://doaj.org/article/deda16c36f5445b9a23062c69d218451
Autor:
Francesco Paolo Di Giorgio, Claudia Cavarischia, Graziella Bovi, Rosella Ombrato, Anna di Matteo, Rosa Buonfiglio, Pier Francesca Porceddu, Rossella Picollo, Beatrice Garrone, Guido Furlotti, Laura Oggianu, Silvana Olivieri, Giorgina Mangano, Federica Prati, Angelo Reggiani
Publikováno v:
ACS Medicinal Chemistry Letters. 11:825-831
Bipolar disorders still represent a global unmet medical need and pose a requirement for novel effective treatments. In this respect, glycogen synthase kinase 3β (GSK-3β) aberrant activity has been linked to the pathophysiology of several disease c
Autor:
Angelo Reggiani, Paolo Di Fruscia, Elisa Romeo, Pier Francesca Porceddu, Ennio Albanesi, Natalia Realini, Fabio Bertozzi, Tiziano Bandiera, Stefania Sgroi, Debora Russo
Publikováno v:
Pharmacological research. 172
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS), in which myeloid cells sustain inflammation, take part in priming, differentiation, and reactivation of myelin-specific T cells, and cause direct myelin da
Autor:
Francesco Paolo Di Giorgio, Angelo Reggiani, Elisa Romeo, Lucia Durando, Pier Francesca Porceddu, Beatrice Garrone, Claudio Milanese, Mariasole Ciampoli
Publikováno v:
Human molecular genetics. 31(6)
Glycogen-synthase kinase 3 (GSK3) is a kinase mediating phosphorylation on serine and threonine amino acid residues of several target molecules. The enzyme is involved in the regulation of many cellular processes and aberrant activity of GSK3 has bee
Autor:
Valeria de Turris, Pier Francesca Porceddu, Alessandro Soloperto, Silvia Di Angelantonio, Silvia Ghirga, Carlo Brighi, Federica Cordella, Federico Salaris, Maria Rosito, Alessandro Rosa, Chiara D’Antoni, Angelo Reggiani
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 5, Pp 1-22 (2021)
Cell Death and Disease, Vol 12, Iss 5, Pp 1-22 (2021)
Fragile X syndrome (FXS) is a neurodevelopmental disorder, characterized by intellectual disability and sensory deficits, caused by epigenetic silencing of the FMR1 gene and subsequent loss of its protein product, fragile X mental retardation protein
Autor:
Silvia Ghirga, S. Di Angelantonio, Pier Francesca Porceddu, Alessandro Rosa, Alessandro Soloperto, Federico Salaris, Federica Cordella, Maria Rosito, Carlo Brighi, Angelo Reggiani, V. de Turris
Fragile X syndrome (FXS) is a neurodevelopmental disorder, characterized by intellectual disability and sensory deficits, caused by epigenetic silencing of the FMR1 gene and subsequent loss of its protein product, fragile X mental retardation protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb8fd5e454d2b8d5f91e7efaefd3d8b
https://doi.org/10.1101/2020.11.12.379800
https://doi.org/10.1101/2020.11.12.379800
Autor:
Mariasole Ciampoli, Maria Summa, Massimiliano Lanfranco, Rosella Ombrato, Pier Francesca Porceddu, Valeria Capurro, Natasha Margaroli, Serena Tongiani, Beatrice Garrone, Lucia Durando, Angelo Reggiani
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 128, Iss, Pp 110249-(2020)
Glycogen synthase kinase 3β (GSK-3β) is a serine/threonine protein kinase mediating phosphorylation on serine and threonine amino acid residues of several target molecules. The enzyme is involved in the regulation of many cellular processes and abe
Autor:
Federica, Prati, Rosa, Buonfiglio, Guido, Furlotti, Claudia, Cavarischia, Giorgina, Mangano, Rossella, Picollo, Laura, Oggianu, Anna, di Matteo, Silvana, Olivieri, Graziella, Bovi, Pier Francesca, Porceddu, Angelo, Reggiani, Beatrice, Garrone, Francesco Paolo, Di Giorgio, Rosella, Ombrato
Publikováno v:
ACS Med Chem Lett
[Image: see text] Bipolar disorders still represent a global unmet medical need and pose a requirement for novel effective treatments. In this respect, glycogen synthase kinase 3β (GSK-3β) aberrant activity has been linked to the pathophysiology of