Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway

Autor: Benedikz, E, Bailey, D, Cook, C, Gonçalves-Carneiro, D, Buckner, M, Blair, J, Wells, T, Fletcher, N, Goodall, M, Flores-Langarica, A, Kingsley, R, Madsen, J, Teeling, J, Johnston, S, Maclennan, C, Balfe, P, Henderson, I, Piddock, L, Cunningham, A, McKeating, J

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

Viruses and bacteria colonize hosts by invading epithelial barriers. Recent studies have shown that interactions between the microbiota, pathogens and the host can potentiate infection through poorly understood mechanisms. Here, we investigated wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::771d8e471d2b01c001a876a92b93ada9
http://link.springer.com/article/10.1038/s41598-019-44263-7

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Antibiotic research and development: business as usual?

Autor: Harbarth, S, Theuretzbacher, U, Hackett, J, collaborators: Adriaenssens, N, Anderson, J, Antonisse, A, Årdal, C, Baillon-Plot, N, Baraldi, E, Bettiol, E, Bhatti, T, Bradshaw, D, Brown, N, Carmeli, Y, Cars, O, Charbonneau, C, Cheng, S, Ciabuschi, F, Cirino, J, Clift, C, Colson, A, Dane, A, De-Lima, N, Dooa, M, Drabik, D, Eisenstein, B, Farquhar, R, Fidan, D, Findlay, D, Galli, F, Gilchrist, K, Gilman, S, Goeschl, T, Goodall, J, Goossens, H, Gouglas, D, Guise, T, Gyssens, I, Hallerbäck, P, Heymann, D, Hoffman, S, Howell, J, Hulscher, M, Hunt, T, Huttner, B, Jantarada, F, Jaquest, D, Joly, F, Ka, L, Karas, A, Knirsch, C, Kullberg, Bj, Laxminarayan, R, Le Maréchal, M, Legros, S, Lilliott, N, Lindgren, E, Longshaw, C, Mahoney, N, Mastrangelo, D, Mcdonald, J, Mckeever, S, Mepham, T, Milanic, R, Monnier, A, Morel, C, Morton, A, Mossialos, E, Nolet, B, Outterson, K, Payne, D, Piddock, L, Plahte, J, Potter, D, Pulcini, C, Rex, J, Ross, E, Rottingen, Ja, Ryan, K, Ryan, J, Salimi, T, Schouten, J, Schultz, S, So, A, Spiesser, J, Stålhammar, No, Stanic, M, Tacconelli, E, Temkin, L, Trick, D, Vink, P, Vlahovic-Palcevski, V, Watt, M, Wells, M, Wesseler, J, White, A, Wood, S, Zanichelli, V, Zorzet, A.

Publikováno v: Journal of Antimicrobial Chemotherapy, 70(6), 1604-1607
Journal of Antimicrobial Chemotherapy, Vol. 70, No 6 (2015) pp. 1604-7
Journal of Antimicrobial Chemotherapy, 70, 6, pp. 1604-7
Journal of Antimicrobial Chemotherapy, 70, 1604-7
Journal of Antimicrobial Chemotherapy 70 (2015) 6

The global burden of antibiotic resistance is tremendous and, without new anti-infective strategies, will continue to increase in the coming decades. Despite the growing need for new antibiotics, few pharmaceutical companies today retain active antib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb01a98a075a6ee9fe2b6f1e57b9330c
https://doi.org/10.1093/jac/dkv020

Prevalence of mutations within the quinolone resistance-determining region of gyrA, gyrB, parC, and parE and association with antibiotic resistance in quinolone-resistant Salmonella enterica

Autor: Gray, Douglas T., Eaves, D. J., Randall, L., Buckley, A., Woodward, M. J., White, A. P., Piddock, L. J.

Salmonella enterica isolates (n = 182) were examined for mutations in the quinolone resistance-determining region of gyrA, gyrB, parC, and parE. The frequency, location, and type of GyrA substitution varied with the serovar. Mutations were found in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7cd86498eb5a7749af877444d403d15b

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