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Crystal structure of the BREX phage defence protein BrxA

Autor: Beck, Izaak N., Picton, David M., Blower, Tim R.

Publikováno v: In Current Research in Structural Biology 2022 4:211-219

Isolation and Characterisation of Bacteriophages with Activity against Invasive Non-Typhoidal Causing Bloodstream Infection in Malawi

Autor: Rodwell, Ella V, Wenner, Nicolas, Pulford, Caisey V, Cai, Yueyi, Bowers-Barnard, Arthur, Beckett, Alison, Rigby, Jonathan, Picton, David M, Blower, Tim R, Feasey, Nicholas, Hinton, Jay C D, Perez-Sepulveda, Blanca M

In recent years, novel lineages of invasive non-typhoidal (iNTS) serovars Typhimurium and Enteritidis have been identified in patients with bloodstream infection in Sub-Saharan Africa. Here, we isolated and characterised 32 phages capable of infectin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::0e99d7a92d36e064feaf950f1d29552a
https://archive.lstmed.ac.uk/17495/3/viruses-13-00478.pdf

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Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.

Autor: Went SC; Department of Biosciences, Durham University, South Road, Durham, UK., Picton DM; Department of Biosciences, Durham University, South Road, Durham, UK., Morgan RD; New England Biolabs, 240 County Road, Ipswich, MA, USA., Nelson A; Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, UK., Brady A; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Mariano G; Department of Microbial Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK., Dryden DTF; Department of Biosciences, Durham University, South Road, Durham, UK., Smith DL; Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, UK., Wenner N; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Hinton JCD; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Blower TR; Department of Biosciences, Durham University, South Road, Durham, UK. timothy.blower@durham.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 22; Vol. 15 (1), pp. 7236. Date of Electronic Publication: 2024 Aug 22.