Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients

Autor: Schwaederle, M, Krishnamurthy, N, Daniels, GA, Piccioni, DE, Kesari, S, Fanta, PT, Schwab, RB, Patel, SP, Parker, BA, Kurzrock, R

Publikováno v: Cancer, vol 124, iss 6
Schwaederle, M; Krishnamurthy, N; Daniels, GA; Piccioni, DE; Kesari, S; Fanta, PT; et al.(2018). Telomerase Reverse Transcriptase Promoter Alterations Across Cancer Types as Detected by Next-Generation Sequencing: A Clinical and Molecular Analysis of 423 Patients. CANCER, 124(6), 1288-1296. doi: 10.1002/cncr.31175. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9ff896np

BACKGROUND:Telomerase reverse transcriptase (TERT) promoter mutations that may affect telomerase activity have recently been described in human malignancies. The purpose of this study was to investigate the clinical correlates of TERT promoter abnorm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0e301dd4452de538a055cb4d6f51282c
https://escholarship.org/uc/item/9ff896np

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Arterial spin labeled perfusion MRI for the assessment of radiation-treated meningiomas.

Autor: Manning P; Department of Radiology, University of California, San Diego, San Diego, CA, United States.; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States., Srinivas S; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States., Bolar DS; Department of Radiology, University of California, San Diego, San Diego, CA, United States.; Center for Functional Magnetic Resonance Imaging, University of California, San Diego, San Diego, CA, United States., Rajaratnam MK; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States., Piccioni DE; Department of Neurosciences, University of California, San Diego, San Diego, CA, United States., McDonald CR; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States.; Department of Neurosciences, University of California, San Diego, San Diego, CA, United States.; Department of Psychiatry, University of California, San Diego, San Diego, CA, United States., Hattangadi-Gluth JA; Department of Radiation Medicine and Applied Sciences, University of California, San Diego, San Diego, CA, United States., Farid N; Department of Radiology, University of California, San Diego, San Diego, CA, United States.; Center for Multimodal Imaging and Genetics, University of California, San Diego, San Diego, CA, United States.; Center for Functional Magnetic Resonance Imaging, University of California, San Diego, San Diego, CA, United States.

Publikováno v: Frontiers in radiology [Front Radiol] 2024 Mar 18; Vol. 4, pp. 1345465. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).

Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.

Autor: Liau LM; Department of Neurosurgery, University of California, Los Angeles., Ashkan K; King's College Hospital, London, United Kingdom., Brem S; Department of Neurosurgery, Penn Brain Tumor Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Campian JL; Division of Neurology, Washington University School of Medicine in St Louis, St Louis, Missouri., Trusheim JE; Givens Brain Tumor Center, Abbott Northwestern Hospital, Minneapolis, Minnesota., Iwamoto FM; Columbia University Irving Medical Center, New York, New York.; New York-Presbyterian Hospital, New York, New York., Tran DD; Preston A. Wells, Jr. Center for Brain Tumor Therapy, Division of Neuro-Oncology, Lillian S. Wells Department of Neurosurgery, University of Florida College of Medicine, Gainesville., Ansstas G; Department of Neurological Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri., Cobbs CS; Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Medical Center, Seattle, Washington., Heth JA; Taubman Medical Center, University of Michigan, Ann Arbor., Salacz ME; Neuro-Oncology Program, Rutgers Cancer Institute of New Jersey, New Brunswick., D'Andre S; Sutter Health, Sacramento, California., Aiken RD; Glasser Brain Tumor Center, Atlantic Healthcare, Summit, New Jersey., Moshel YA; Glasser Brain Tumor Center, Atlantic Healthcare, Summit, New Jersey., Nam JY; Department of Neurological Sciences, Rush Medical College, Chicago, Illinois., Pillainayagam CP; Department of Neurology, The Ohio State University, Columbus., Wagner SA; The Cancer Center of Columbus Regional Health, Columbus, Indiana., Walter KA; University of Rochester, Rochester, New York., Chaudhary R; University of Cincinnati, Cincinnati, Ohio., Goldlust SA; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, New Jersey., Lee IY; Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan., Bota DA; Department of Neurology and Chao Family Comprehensive Cancer Center, University of California, Irvine., Elinzano H; Rhode Island Hospital, Providence., Grewal J; Long Island Brain Tumor Center at NSPC, Lake Success, New York., Lillehei K; Department of Neurosurgery, University of Colorado Health Sciences Center, Boulder., Mikkelsen T; Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan., Walbert T; Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan., Abram S; Ascension St Thomas Brain and Spine Tumor Center, Howell Allen Clinic, Nashville, Tennessee., Brenner AJ; Mays Cancer Center at UT Health San Antonio, San Antonio, Texas., Ewend MG; Department of Neurosurgery, UNC School of Medicine and UNC Health, Chapel Hill, North Carolina., Khagi S; The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Lovick DS; Advent Health, Kansas City, Kansas., Portnow J; Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, California., Kim L; Division of Neuro-Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Loudon WG; Saint Joseph's Hospital, Orange, California., Martinez NL; Jefferson Hospital for Neurosciences, Jefferson University, Philadelphia, Pennsylvania., Thompson RC; Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee., Avigan DE; Beth Israel Deaconess Medical Center, Harvard Medical School, Cambridge, Massachusetts., Fink KL; Baylor Scott & White Neuro-Oncology Associates, Dallas, Texas., Geoffroy FJ; Illinois Cancer Care, Galesburg, Peoria., Giglio P; Medical University of South Carolina Neurosciences, Charleston., Gligich O; Mount Sinai Medical Center, Miami Beach, Florida., Krex D; Uniklinikum Dresden, Dresden, Germany., Lindhorst SM; Hollings Cancer Center, Medical University of South Carolina, Charleston., Lutzky J; Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida., Meisel HJ; BG Klinikum Bergmannstrost, Halle, Germany., Nadji-Ohl M; Neurochirurgie Katharinenhospital, Klinikum der Landeshauptstadt Stuttgart, Stuttgart, Germany., Sanchin L; BG Klinikum Bergmannstrost, Halle, Germany., Sloan A; Seidman Cancer Center, University Hospitals-Cleveland Medical Center, Cleveland, Ohio., Taylor LP; Department of Neurosurgery, Tufts Medical Center, Boston, Massachusetts., Wu JK; Department of Neurosurgery, Tufts Medical Center, Boston, Massachusetts., Dunbar EM; Piedmont Physicians Neuro-Oncology, Piedmont Brain Tumor Center, Atlanta, Georgia., Etame AB; Department of Neuro-Oncology, Moffitt Cancer Center., Kesari S; Pacific Neurosciences Institute and Saint John's Cancer Institute, Santa Monica, California., Mathieu D; Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Piccioni DE; UC San Diego Moore's Cancer Center, La Jolla, California., Baskin DS; Department of Neurosurgery, Houston Methodist Hospital, Houston, Texas., Lacroix M; Geisinger Neuroscience Institute, Danville, Pennsylvania., May SA; Klinik für Neurochirurgie, Chemnitz, Germany., New PZ; Baptist Health System, San Antonio, Texas., Pluard TJ; Saint Luke's Cancer Institute, Kansas City, Missouri., Toms SA; Departments of Neurosurgery and Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island., Tse V; Kaiser Permanente, Redwood City, California., Peak S; Kaiser Permanente, Redwood City, California., Villano JL; University of Kentucky Markey Cancer Center, Department of Medicine, Neurosurgery, and Neurology, University of Kentucky, Lexington., Battiste JD; Oklahoma University Health Science Center, Oklahoma City., Mulholland PJ; University College London Hospitals, London, United Kingdom., Pearlman ML; Blue Sky Neurology/Neuro-Oncology, Englewood, California., Petrecca K; Department of Neurology and Neurosurgery, Montreal Neurological Institute-Hospital, McGill University, Montreal, Quebec, Canada., Schulder M; Department of Neurosurgery, Zucker School of Medicine at Hofstra/Northwell, Uniondale, New York., Prins RM; University of California, Los Angeles., Boynton AL; Northwest Biotherapeutics, Inc, Bethesda, Maryland., Bosch ML; Northwest Biotherapeutics, Inc, Bethesda, Maryland.

Publikováno v: JAMA oncology [JAMA Oncol] 2023 Jan 01; Vol. 9 (1), pp. 112-121.

A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies.

Autor: Fu S; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. siqingfu@mdanderson.org., Piccioni DE; UCSD Moores Cancer Center, San Diego, CA, USA., Liu H; University of Chicago Medical Center, Chicago, IL, USA., Lukas RV; Northwestern University, Chicago, IL, USA.; Lou and Jean Malnati Brain Tumor Institute, Chicago, IL, USA., Kesari S; Saint John's Cancer Institute and Pacific Neuroscience Institute, Santa Monica, CA, USA., Aregawi D; Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA., Hong DS; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA., Yamaguchi K; Sumitomo Dainippon Pharma Co., Ltd., Tokyo, Japan., Whicher K; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA., Zhang Y; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA., Chen YL; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA., Poola N; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA.; Otsuka Pharmaceuticals, Princeton, NJ, USA., Eddy J; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA.; Morphic Therapeutic, Waltham, MA, USA., Blum D; Sunovion Pharmaceuticals Inc., Marlborough, MA, USA.

Publikováno v: Scientific reports [Sci Rep] 2021 Nov 16; Vol. 11 (1), pp. 22355. Date of Electronic Publication: 2021 Nov 16.