Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.

Autor: Saez-Atienzar S; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health (NIH), Bethesda, MD 20892, USA; Department of Neurology, Ohio State University, Columbus, OH 43210, USA. Electronic address: sara.saezatienzar@osumc.edu., Souza CDS; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Chia R; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health (NIH), Bethesda, MD 20892, USA., Beal SN; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Lorenzini I; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Huang R; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20850, USA., Levy J; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Burciu C; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Ding J; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Gibbs JR; Computational Biology Group, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Jones A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Dewan R; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health (NIH), Bethesda, MD 20892, USA., Pensato V; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Peverelli S; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy., Corrado L; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., van Vugt JJFA; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., van Rheenen W; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Tunca C; Neurodegeneration Research Laboratory (NDAL), Research Center for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey., Bayraktar E; Neurodegeneration Research Laboratory (NDAL), Research Center for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey., Xia M; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20850, USA., Iacoangeli A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; National Institute for Health Research Biomedical Research Centre and Dementia Unit, South London and Maudsley NHS Foundation Trust and King's College London, London, UK., Shatunov A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Tiloca C; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy., Ticozzi N; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Verde F; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Mazzini L; Amyotrophic Lateral Sclerosis Center, Department of Neurology 'Maggiore della Carità' University Hospital, Novara, Italy., Kenna K; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Al Khleifat A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Opie-Martin S; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Raggi F; Department of Neurosciences, University of Padova, Padova, Italy., Filosto M; NeMO-Brescia Clinical Center for Neuromuscular Diseases, University of Brescia, Brescia, Italy; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Piccinelli SC; NeMO-Brescia Clinical Center for Neuromuscular Diseases, University of Brescia, Brescia, Italy; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Padovani A; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Gagliardi S; Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy., Inghilleri M; Department of Human Neurosciences, Rare Neuromuscular Diseases Centre, Sapienza University, 00185 Rome, Italy; IRCCS Neuromed, Pozzilli, Italy., Ferlini A; Unit of Medical Genetics, Department of Medical Science, University of Ferrara, Ferrara, Italy., Vasta R; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Calvo A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy., Moglia C; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy., Canosa A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy; Institute of Cognitive Sciences and Technologies, C.N.R., Rome, Italy., Manera U; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy., Grassano M; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Mandrioli J; Department of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena, Italy., Mora G; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Lunetta C; Department of Neurorehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Milan, Milan, Italy; NEMO Clinical Center Milano, Fondazione Serena Onlus, Milan, Italy., Tanel R; Operative Unit of Neurology, S. Chiara Hospital, Trento, Italy., Trojsi F; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Cardinali P; Neurology Unit, AST Fermo, Marche, Italy., Gallone S; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Brunetti M; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy., Galimberti D; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; Department of Biomedical, Surgical, and Dental Sciences, University of Milan, Milan, Italy., Serpente M; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Fenoglio C; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; Department of Biomedical, Surgical, and Dental Sciences, University of Milan, Milan, Italy., Scarpini E; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Comi GP; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy; Neurology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Corti S; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy; Neurology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Del Bo R; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy; Neurology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy., Ceroni M; Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy., Pinter GL; 3rd Neurology Unit, Motor Neuron Diseases Center, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Taroni F; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Bella ED; 3rd Neurology Unit, Motor Neuron Diseases Center, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy., Bersano E; 3rd Neurology Unit, Motor Neuron Diseases Center, Fondazione IRCCS Istituto Neurologico 'Carlo Besta,' Milan, Italy; 'L. Sacco' Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, Italy., Curtis CJ; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London, UK; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM), London, UK., Lee SH; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London, UK; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM), London, UK., Chung R; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London, UK; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM), London, UK., Patel H; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM), London, UK., Morrison KE; School of Medicine, Dentistry, and Biomedical Sciences, Faculty of Medicine Health and Life Sciences, Queen's University, Belfast, UK., Cooper-Knock J; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK., Shaw PJ; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, and the NIHR Sheffield Biomedical Research Centre, Sheffield, UK., Breen G; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London, UK; NIHR BioResource Centre Maudsley, NIHR Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM), London, UK., Dobson RJB; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, UK; NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK; Health Data Research UK London, University College London, London, UK; Institute of Health Informatics, University College London, London, UK; NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust, London, UK., Dalgard CL; Department of Anatomy, Physiology, & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA; The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Scholz SW; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892, USA; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD 21287, USA., Al-Chalabi A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; Department of Clinical Neuroscience, King's College Hospital, London SE5 9RS, UK., van den Berg LH; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., McLaughlin R; Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Hardiman O; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; Department of Neurology, Beaumont Hospital, Dublin, Ireland., Cereda C; Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy., Sorarù G; Department of Neurosciences, University of Padova, Padova, Italy., D'Alfonso S; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., Chandran S; Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Pal S; Euan MacDonald Centre for Motor Neurone Disease Research, Edinburgh, UK; Centre for Neuroregeneration and Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK., Ratti A; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy., Gellera C; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Johnson K; Bioinformatics Section, Information Technology Program (ITP), Division of Intramural Research (DIR), National Institute of Neurological Disorders & Stroke, NIH, Bethesda, MD 20892, USA., Doucet-O'Hare T; Neuro-oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, MD 20892, USA., Pasternack N; Translational Neuroscience Center, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892, USA., Wang T; Translational Neuroscience Center, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892, USA., Nath A; Translational Neuroscience Center, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892, USA., Siciliano G; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Silani V; Department of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center, Università degli Studi di Milano, Milan, Italy., Başak AN; Neurodegeneration Research Laboratory (NDAL), Research Center for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey., Veldink JH; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Camu W; ALS Center, CHU Gui de Chauliac, University of Montpellier, Montpellier, France., Glass JD; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Landers JE; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Chiò A; 'Rita Levi Montalcini' Department of Neuroscience, Amyotrophic Lateral Sclerosis Center, University of Turin, Turin, Italy; Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy; Institute of Cognitive Sciences and Technologies, C.N.R., Rome, Italy., Sattler R; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Shaw CE; United Kingdom Dementia Research Institute, Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK; Centre for Brain Research, University of Auckland, Auckland, New Zealand., Ferraiuolo L; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Fogh I; United Kingdom Dementia Research Institute, Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Traynor BJ; Neuromuscular Diseases Research Section, National Institute on Aging, National Institutes of Health (NIH), Bethesda, MD 20892, USA; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD 21287, USA; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, University College London, London WC1N 1PJ, UK; National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD 20892, USA; RNA Therapeutics Laboratory, National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD 20850, USA. Electronic address: traynorb@mail.nih.gov.

Publikováno v: Cell genomics [Cell Genom] 2024 Nov 13; Vol. 4 (11), pp. 100679. Date of Electronic Publication: 2024 Oct 21.

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial.

Autor: Beghi E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Pupillo E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Bianchi E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Bonetto V; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Luotti S; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Pasetto L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Bendotti C; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Tortarolo M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Sironi F; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Camporeale L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy., Sherman AV; Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Paganoni S; Sean M. Healey and AMG Center for ALS at Mass General Hospital, Department of Neurology, Boston, Massachusetts, USA.; Spaulding Rehabilitation Hospital, Department of PM&R, Harvard Medical School, Boston, Massachusetts, USA., Scognamiglio A; ALS Expert Center 'Maggiore della Carità' Hospital and University of Piemonte Orientale, Novara, Italy., De Marchi F; ALS Expert Center 'Maggiore della Carità' Hospital and University of Piemonte Orientale, Novara, Italy., Bongioanni P; Spinal Cord Injuries Section, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Del Carratore R; Institute of Clinical Physiology, CNR-, Pisa, Italy., Caponnetto C; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Diamanti L; IRCCS Mondino Foundation, Pavia, Italy., Martinelli D; IRCCS Mondino Foundation, Pavia, Italy., Calvo A; Centro Regionale Esperto per la Sclerosi Laterale Amiotrofica, Dipartimento di Neuroscienze 'Rita Levi Montalcini', Università degli Studi di Torino, AOU Città della Salute e della Scienza di Torino, Torino, Italy., Filosto M; Department of Clinical and Experimental Sciences, University of Brescia, Gussago Brescia, Italy., Padovani A; Department of Clinical and Experimental Sciences, University of Brescia, Gussago Brescia, Italy., Piccinelli SC; Department of Clinical and Experimental Sciences, University of Brescia, Gussago Brescia, Italy., Ricci C; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Dalla Giacoma S; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., De Angelis N; Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy., Inghilleri M; Università di Roma 'Sapienza' UOSD Malattie Neurodegenerative, Centro Malattie Rare Neuromuscolari Policlinico Universitario Umberto I, Roma, Italy., Spataro R; ALS Clinical Research Center, AOUP 'P Giaccone' - University of Palermo, Palermo, Italy., La Bella V; ALS Clinical Research Center, AOUP 'P Giaccone' - University of Palermo, Palermo, Italy., Logroscino G; Center for neurodegenerative diseases and the Aging Brain, Department of Clinical Research in Neurology of the University of Bari at 'Pia Fondazione Card G. Panico 'Hospital Tricase, Tricase, Italy.; Department of Basic Medicine Neuroscience and Sense Organs, University Aldo Moro Bari, Bari, Italy., Lunetta C; Centro Clinico NeMO Milano, Fondazione Serena ONLUS, Milan, Italy., Tarlarini C; Centro Clinico NeMO Milano, Fondazione Serena ONLUS, Milan, Italy., Mandrioli J; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Department of Neurosciences, Azienda Ospedaliero-Universitaria Di Modena, Modena, Italy., Martinelli I; Department of Neurosciences, Azienda Ospedaliero-Universitaria Di Modena, Modena, Italy.; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy., Simonini C; Department of Neurosciences, Azienda Ospedaliero-Universitaria Di Modena, Modena, Italy., Zucchi E; Department of Neurosciences, Azienda Ospedaliero-Universitaria Di Modena, Modena, Italy.; Neuroscience PhD Program, University of Modena and Reggio Emilia, Modena, Italy., Monsurrò MR; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy., Ricciardi D; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy., Trojsi F; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy., Riva N; Neurology Unit, Neurorehabilitation Unit, and Neurophysiology Unit, Vita-Salute San Raffaele University and San Raffaele Scientific Institute, Milan, Italy., Filippi M; Neurology Unit, Neurorehabilitation Unit, and Neurophysiology Unit, Vita-Salute San Raffaele University and San Raffaele Scientific Institute, Milan, Italy., Simone IL; Neurology Unit, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, Bari, Italy., Sorarù G; Motor Neuton Disease Center, Department of Neurosciences, Azienda Ospedale Università di Padova, Padova, Italy., Spera C; Azienda Ospedaliera 'S Maria' Terni, Terni, Italy., Florio L; Neurology Department, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Messina S; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Russo M; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Siciliano G; Department of clinical and experimental medicine, University of Pisa, Pisa, Italy., Conte A; Centro Clinico NEMO-Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy., Saddi MV; Neurology Department, San Francesco Hospital, Nuoro, Italy., Carboni N; Neurology Department, San Francesco Hospital, Nuoro, Italy., Mazzini L; ALS Expert Center 'Maggiore della Carità' Hospital and University of Piemonte Orientale, Novara, Italy.

Publikováno v: European journal of neurology [Eur J Neurol] 2023 Jan; Vol. 30 (1), pp. 69-86. Date of Electronic Publication: 2022 Oct 07.

Clinical outcome of neurological patients with COVID-19: the impact of healthcare organization improvement between waves.

Autor: Cristillo V; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy. viviana.cristillo@gmail.com., Pilotto A; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Benussi A; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Libri I; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Giunta M; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Morotti A; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Gipponi S; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Locatelli M; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Piccinelli SC; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Mazzoleni V; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., di Cola FS; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Masciocchi S; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Pezzini D; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Scalvini A; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Premi E; Stroke Unit, Azienda Socio Sanitaria Territoriale Spedali Civili, Spedali Civili Hospital, Brescia, Italy., Cottini E; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy., Gamba M; Stroke Unit, Azienda Socio Sanitaria Territoriale Spedali Civili, Spedali Civili Hospital, Brescia, Italy., Magoni M; Stroke Unit, Azienda Socio Sanitaria Territoriale Spedali Civili, Spedali Civili Hospital, Brescia, Italy., Fontanella MM; Neurosurgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Spedali Civili di Brescia, Brescia, Italy., Padovani A; Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, P. le Spedali Civili 1, 25123, Brescia, Italy.

Publikováno v: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2022 May; Vol. 43 (5), pp. 2923-2927. Date of Electronic Publication: 2022 Feb 17.

Prolonged distal motor latency of median nerve does not improve diagnostic accuracy for CIDP.

Autor: Spina E; Department of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Via Pansini, 5, 81025, Naples, Italy. ema.spina@libero.it., Doneddu PE; Neuromuscular and Neuroimmunology Service, IRCCS Humanitas Clinical and Research Institute, Rozzano, Milan, Italy., Liberatore G; Neuromuscular and Neuroimmunology Service, IRCCS Humanitas Clinical and Research Institute, Rozzano, Milan, Italy., Cocito D; Presidio Sanitario Major, Istituti Clinici Scientifici Maugeri, Turin, Italy., Fazio R; Division of Neuroscience, Department of Neurology, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy., Briani C; Department of Neuroscience, Neurology Unit, University of Padova, Padova, Italy., Filosto M; Center for Neuromuscular Diseases and Neuropathies, Unit of Neurology, ASST 'Spedali Civili', University of Brescia, Brescia, Italy., Benedetti L; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa and IRCCS San Martino, Genoa, Italy.; IRCCS AOU San Martino-IST, Genoa, Italy., Antonini G; Unit of Neuromuscular Diseases, Department of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sant'Andrea Hospital, 'Sapienza' University of Rome, Rome, Italy., Cosentino G; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.; IRCCS Mondino Foundation, Pavia, Italy., Jann S; Department of Neuroscience, Niguarda Ca' Granda Hospital, Milan, Italy., Mazzeo A; Department of Clinical and Experimental Medicine, Unit of Neurology, University of Messina, Messina, Italy., Cortese A; IRCCS Mondino Foundation, Pavia, Italy.; Molecular Neurosciences, University College London, London, UK., Marfia GA; Dysimmune Neuropathies Unit, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy., Clerici AM; Neurology Unit, Circolo and Macchi Foundation Hospital, Insubria University, DBSV, Varese, Italy., Siciliano G; Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Carpo M; Neurology Unit, ASST Bergamo Ovest-Ospedale Treviglio, Treviglio, Italy., Luigetti M; UOC Neurologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.; Dipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, Rome, Italy., Lauria G; Unit of Neuroalgology, IRCCS Foundation 'Carlo Besta' Neurological Institute, Milan, Italy.; Department of Biomedical and Clinical Sciences 'Luigi Sacco', University of Milan, Milan, Italy., Rosso T; ULSS2 Marca Trevigiana, UOC Neurologia-Castelfranco Veneto, Treviso, Italy., Cavaletti G; School of Medicine and Surgery and Experimental Neurology Unit, University of Milano-Bicocca, Monza, Italy., Peci E; Presidio Sanitario Major, Istituti Clinici Scientifici Maugeri, Turin, Italy., Tronci S; Division of Neuroscience, Department of Neurology, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy., Ruiz M; Department of Neuroscience, Neurology Unit, University of Padova, Padova, Italy., Piccinelli SC; Center for Neuromuscular Diseases and Neuropathies, Unit of Neurology, ASST 'Spedali Civili', University of Brescia, Brescia, Italy., Schenone A; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa and IRCCS San Martino, Genoa, Italy., Leonardi L; Unit of Neuromuscular Diseases, Department of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sant'Andrea Hospital, 'Sapienza' University of Rome, Rome, Italy., Gentile L; Department of Clinical and Experimental Medicine, Unit of Neurology, University of Messina, Messina, Italy., Piccolo L; IRCCS Mondino Foundation, Pavia, Italy., Mataluni G; Dysimmune Neuropathies Unit, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy., Santoro L; Department of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Via Pansini, 5, 81025, Naples, Italy., Nobile-Orazio E; Neuromuscular and Neuroimmunology Service, IRCCS Humanitas Clinical and Research Institute, Rozzano, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Milan University, Milan, Italy., Manganelli F; Department of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Via Pansini, 5, 81025, Naples, Italy.

Publikováno v: Journal of neurology [J Neurol] 2022 Feb; Vol. 269 (2), pp. 907-912. Date of Electronic Publication: 2021 Jun 26.

Electrophysiological features of acute inflammatory demyelinating polyneuropathy associated with SARS-CoV-2 infection.

Autor: Uncini A; Department of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio', Chieti, Italy. Electronic address: uncini@unich.it., Foresti C; Neuropathophysiology, 'Papa Giovanni XXIII' Hospital, Bergamo, Italy., Frigeni B; Neuropathophysiology, 'Papa Giovanni XXIII' Hospital, Bergamo, Italy., Storti B; Neuropathophysiology, 'Papa Giovanni XXIII' Hospital, Bergamo, Italy., Servalli MC; Neuropathophysiology, 'Papa Giovanni XXIII' Hospital, Bergamo, Italy., Gazzina S; Neuropathophysiology, ASST Spedali Civili, Brescia, Italy., Cosentino G; Department of Brain and Behavioral Sciences, University of Pavia and IRCCS Mondino Foundation, Pavia, Italy., Bianchi F; Neurology and Neurophysiology Unit, IRCCS San Raffaele Scientific Institute, Vita Salute San Raffaele University, Milano, Italy., Del Carro U; Neurology and Neurophysiology Unit, IRCCS San Raffaele Scientific Institute, Vita Salute San Raffaele University, Milano, Italy., Alfonsi E; IRCCS Mondino Foundation, Pavia, Italy., Piccinelli SC; Center for Neuromuscular Diseases, Unit of Neurology, ASST Spedali Civili and University of Brescia, Brescia, Italy., De Maria G; Neuropathophysiology, ASST Spedali Civili, Brescia, Italy., Padovani A; Center for Neuromuscular Diseases, Unit of Neurology, ASST Spedali Civili and University of Brescia, Brescia, Italy., Filosto M; Center for Neuromuscular Diseases, Unit of Neurology, ASST Spedali Civili and University of Brescia, Brescia, Italy., Ippoliti L; Statistics Unit, Department of Economics, University 'G. d'Annunzio', Pescara, Italy.

Publikováno v: Neurophysiologie clinique = Clinical neurophysiology [Neurophysiol Clin] 2021 Mar; Vol. 51 (2), pp. 183-191. Date of Electronic Publication: 2021 Feb 18.