Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Piapi A"'
Autor:
John E. G. Lawrence, Kenny Roberts, Elizabeth Tuck, Tong Li, Lira Mamanova, Petra Balogh, Inga Usher, Alice Piapi, Pavel Mazin, Nathaniel D. Anderson, Liam Bolt, Laura Richardson, Elena Prigmore, Xiaoling He, Roger A. Barker, Adrienne Flanagan, Matthew D. Young, Sarah A. Teichmann, Omer Bayraktar, Sam Behjati
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Positional coding along the anterior-posterior axis is regulated by HOX genes, whose 3’ to 5’ expression correlates with location along this axis. The precise utilisation of HOX genes in different human cell types is not fully understood
Externí odkaz:
https://doaj.org/article/faf1fdd958e64b8d8005dc5935c1516e
Autor:
Gerda Kildisiute, Maria Kalyva, Rasa Elmentaite, Stijn van Dongen, Christine Thevanesan, Alice Piapi, Kirsty Ambridge, Elena Prigmore, Muzlifah Haniffa, Sarah A. Teichmann, Karin Straathof, Isidro Cortés-Ciriano, Sam Behjati, Matthew D. Young
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background As normal cells transform into cancers, their cell state changes, which may drive cancer cells into a stem-like or more primordial, foetal, or embryonic cell state. The transcriptomic profile of this final state may encode informa
Externí odkaz:
https://doaj.org/article/812f3b2924404e51948b8b5e13fcb34b
Autor:
Mi K. Trinh, Clarissa N. Pacyna, Gerda Kildisiute, Christine Thevanesan, Alice Piapi, Kirsty Ambridge, Nathaniel D. Anderson, Eleonora Khabirova, Elena Prigmore, Karin Straathof, Sam Behjati, Matthew D. Young
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
The identification of cancer cells from single cell transcriptomes can be improved by detecting allelic imbalances due to copy number changes.
Externí odkaz:
https://doaj.org/article/220e9b9e0e1441249c0e227b1bf2a3ec
Akademický článek
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Autor:
Lawrence, John E. G., Roberts, Kenny, Tuck, Elizabeth, Li, Tong, Mamanova, Lira, Balogh, Petra, Usher, Inga, Piapi, Alice, Mazin, Pavel, Anderson, Nathaniel D., Bolt, Liam, Richardson, Laura, Prigmore, Elena, He, Xiaoling, Barker, Roger A., Flanagan, Adrienne, Young, Matthew D., Teichmann, Sarah A., Bayraktar, Omer, Behjati, Sam
Publikováno v:
Nature Communications; 11/20/2024, Vol. 15 Issue 1, p1-18, 18p
Autor:
Alastair Hotblack, Evangelia K. Kokalaki, Morgan J. Palton, Gordon Weng-Kit Cheung, Iwan P. Williams, Somayya Manzoor, Thomas I. Grothier, Alice Piapi, Valeria Fiaccadori, Patrycja Wawrzyniecka, Harriet A. Roddy, Giulia Agliardi, Claire Roddie, Shimobi Onuoha, Simon Thomas, Shaun Cordoba, Martin Pule
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Chimeric antigen receptor (CAR) T cells are a promising form of cancer immunotherapy, although they are often associated with severe toxicities. Here, we present a split-CAR design incorporating separate antigen recognition and intracellular
Externí odkaz:
https://doaj.org/article/dee4a8da64cb4a34bd085ebded529484
Autor:
Matthew D. Young, Thomas J. Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez, Kwasi Kwakwa, Eleonora Khabirova, Gerda Kildisiute, Thomas R. W. Oliver, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Federico Comitani, Alice Piapi, Eva Bugallo-Blanco, Christine Thevanesan, Christina Burke, Elena Prigmore, Kirsty Ambridge, Kenny Roberts, Felipe A. Vieira Braga, Tim H. H. Coorens, Ignacio Del Valle, Anna Wilbrey-Clark, Lira Mamanova, Grant D. Stewart, Vincent J. Gnanapragasam, Dyanne Rampling, Neil Sebire, Nicholas Coleman, Liz Hook, Anne Warren, Muzlifah Haniffa, Marcel Kool, Stefan M. Pfister, John C. Achermann, Xiaoling He, Roger A. Barker, Adam Shlien, Omer A. Bayraktar, Sarah A. Teichmann, Frank C. Holstege, Kerstin B. Meyer, Jarno Drost, Karin Straathof, Sam Behjati
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Transcriptomic analysis may provide information about the differentiation state and cell of origin of a cancer. Here, the authors assess mRNA signals in 1300 childhood and adult renal tumors and report a fetal origin of childhood tumors and no dediff
Externí odkaz:
https://doaj.org/article/07a679f9a06e4d84ac2da9b571bfc2a4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Eleonora Khabirova, Laura Jardine, Tim H. H. Coorens, Simone Webb, Taryn D. Treger, Justin Engelbert, Tarryn Porter, Elena Prigmore, Grace Collord, Alice Piapi, Sarah A. Teichmann, Sarah Inglott, Owen Williams, Olaf Heidenreich, Matthew D. Young, Karin Straathof, Simon Bomken, Jack Bartram, Muzlifah Haniffa, Sam Behjati
Funder: Lister Institute of Preventive Medicine; doi: https://doi.org/10.13039/501100001255
Funder: Newcastle NIHR-Biomedical Research Centre
KMT2A-rearranged infant ALL is an aggressive childhood leukemia with poor prognosis. Here, we inve
Funder: Newcastle NIHR-Biomedical Research Centre
KMT2A-rearranged infant ALL is an aggressive childhood leukemia with poor prognosis. Here, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd33f1816816ca4a0632e3173b9c068
https://www.repository.cam.ac.uk/handle/1810/336209
https://www.repository.cam.ac.uk/handle/1810/336209
