Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pia Soronen"'
Autor:
Jouko Miettunen, Marjo-Riitta Järvelin, Tiina Paunio, Anu Loukola, Leena Peltonen, Juha Veijola, Emma S Nyman, Sonja Sulkava, Pia Soronen, Virpi Leppä, Matti Joukamaa, Pirjo Mäki, Nelson Freimer
Publikováno v:
BMJ Open, Vol 1, Iss 1 (2011)
Objectives Depression is a worldwide leading cause of morbidity and disability. Genetic studies have recently begun to elucidate its molecular aetiology. The authors investigated candidate genes of monoamine neurotransmission and early environmental
Externí odkaz:
https://doaj.org/article/a485ee03299d4f7491706eed6544347d
Autor:
Siddheshwar J Utge, Pia Soronen, Anu Loukola, Erkki Kronholm, Hanna M Ollila, Sami Pirkola, Tarja Porkka-Heiskanen, Timo Partonen, Tiina Paunio
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9259 (2010)
Disturbances in the circadian pacemaker system are commonly found in individuals with depression and sleep-related problems. We hypothesized that some of the canonical circadian clock genes would be associated with depression accompanied by signs of
Externí odkaz:
https://doaj.org/article/c574ebcdbab043a18d593cd3ff463f92
Autor:
Catharina Lavebratt, Louise K Sjöholm, Pia Soronen, Tiina Paunio, Marquis P Vawter, William E Bunney, Rolf Adolfsson, Yvonne Forsell, Joseph C Wu, John R Kelsoe, Timo Partonen, Martin Schalling
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9407 (2010)
Abnormalities in the circadian clockwork often characterize patients with major depressive and bipolar disorders. Circadian clock genes are targets of interest in these patients. CRY2 is a circadian gene that participates in regulation of the evening
Externí odkaz:
https://doaj.org/article/9f0d46ffcd084beeb2af3b64be22e7f9
Autor:
Mikko Ketokivi, Tiina Paunio, Rudolf Uher, Tarja Melartin, Pia Soronen, Erkki Isometsä, Outi Mantere, Pekka Jylhä
Publikováno v:
Depression and Anxiety. 29:816-823
Background We previously reported an association between P2RX7 variant rs208294, diagnosis, and the longitudinal course of mood disorders. Here, we test whether the personality trait neuroticism mediates the effect of P2RX7 on the course of mood diso
Autor:
Pia Soronen, Timo Partonen, Erkki Kronholm, Markus Perola, Hanna Ollila, Tiina Paunio, Siddheshwar Utge, Anu Loukola, Tarja Porkka-Heiskanen, Veikko Salomaa
Publikováno v:
Sleep. 34:1309-1316
STUDY OBJECTIVES Sleeping 7 to 8 hours per night appears to be optimal, since both shorter and longer sleep times are related to increased morbidity and mortality. Depressive disorder is almost invariably accompanied by disturbed sleep, leading to de
Autor:
P. Arvilommi, Kirsi Suominen, Pekka Jylhä, Irina Holma, Heikki Rytsälä, Pia Soronen, Erkki Isometsä, Outi Mantere, Mikael Holma, H. Valtonen, Tiina Paunio, Maria Vuorilehto, Jari Haukka, Tarja Melartin
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156:435-447
We investigated the effect of nine candidate genes on risk for mood disorders, hypothesizing that predisposing gene variants not only elevate the risk for mood disorders but also result in clinically significant differences in the clinical course of
Autor:
Tiina Paunio, Outi M. Palo, Annamari Tuulio-Henriksson, Jouko Lönnqvist, Tuula Kieseppä, Pia Soronen, Mervi Antila, Jari Haukka, Timo Partonen
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :802-808
Bipolar disorder is highly heritable. Cognitive dysfunctions often observed in bipolar patients and their unaffected relatives implicate that these impairments may be associated with genetic predisposition to bipolar disorder and thus fulfill the cri
Autor:
Pia, Soronen
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 130(6)
Patients with the same diagnosis may present a highly different symptom picture. The concept of endophenotype has been created to facilitate the assessment of factors underlying psychiatric diseases. The concept allows the reduction of heterogenous c
Autor:
Tiina Paunio, Annamari Tuulio-Henriksson, Timo Partonen, Jouko Lönnqvist, Mervi Antila, Kaisa Silander, Pia Soronen, Leena Peltonen, Tuula Kieseppä, O M Palo, Hanna Ollila
Publikováno v:
Molecular Psychiatry. 15:4-6
Replication of GWAS of bipolar disorder: association of SNPs near CDH7 with bipolar disorder and visual processing
Autor:
Hanna Ollila, Mari A. Kaunisto, Pia Soronen, Timo Partonen, Jan-Erik Lönnqvist, Tiina Paunio, Tuula Kieseppä, O M Palo, Kaisa Silander, Leena Peltonen
Publikováno v:
Molecular Psychiatry. 14:351-353
Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort