Characterization of Highly Mucus-Adherent Non-GMO Derivatives of Lacticaseibacillus rhamnosus GG

Autor: Pia Rasinkangas, Hanne L. P. Tytgat, Jarmo Ritari, Justus Reunanen, Seppo Salminen, Airi Palva, François P. Douillard, Willem M. de Vos

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Lacticaseibacillus rhamnosus GG is one of the best studied lactic acid bacteria in the context of probiotic effects. L. rhamnosus GG has been shown to prevent diarrhea in children and adults and has been implicated to have mitigating or preventive ef

Externí odkaz: https://doaj.org/article/2658bef2503245958095fbcec3ef468d

Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Elderly (Saimes Study)

Autor: Adele Costabile, Triana Bergillos-Meca, Pia Rasinkangas, Katri Korpela, Willem M. de Vos, Glenn R. Gibson

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

BackgroundThe aging process leads to a potential decline in immune function and adversely affects the gut microbiota. To date, many in vitro and in vivo studies focused on the application of synbiotics (prebiotics combined with probiotics) as a promi

Externí odkaz: https://doaj.org/article/93c7b71af0b34a588d7cfc19aab6b694

Genotypic and phenotypic diversity of Lactobacillus rhamnosus clinical isolates, their comparison with strain GG and their recognition by complement system.

Autor: Eija Nissilä, François P Douillard, Jarmo Ritari, Lars Paulin, Hanna M Järvinen, Pia Rasinkangas, Karita Haapasalo, Seppo Meri, Hanna Jarva, Willem M de Vos

Publikováno v: PLoS ONE, Vol 12, Iss 5, p e0176739 (2017)

Lactobacillus rhamnosus strains are ubiquitous in fermented foods, and in the human body where they are commensals naturally present in the normal microbiota composition of gut, vagina and skin. However, in some cases, Lactobacillus spp. have been im

Externí odkaz: https://doaj.org/article/a84d7c92cdbf474db14530c70366d867

Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili.

Autor: Hanne L P Tytgat, Nienke H van Teijlingen, Ruby May A Sullan, François P Douillard, Pia Rasinkangas, Marcel Messing, Justus Reunanen, Reetta Satokari, Jos Vanderleyden, Yves F Dufrêne, Teunis B H Geijtenbeek, Willem M de Vos, Sarah Lebeer

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151824 (2016)

Mapping of the microbial molecules underlying microbiota-host interactions is key to understand how microbiota preserve mucosal homeostasis. A pivotal family of such bacterial molecules are pili. Pili are proteinaceous cell wall appendages with a wel

Externí odkaz: https://doaj.org/article/bc6e4b1ffdf442999b109489c17f07e7

Selection and characterization of a SpaCBA pilus-secreting food-grade derivative of Lacticaseibacillus rhamnosus GG

Autor: Airi Palva, Steven Aalvink, Justus Reunanen, Jarmo Ritari, Willem M. de Vos, Hanne L. P. Tytgat, Chia-Wei Lin, François P. Douillard, Pia Rasinkangas

Publikováno v: Applied Microbiology and Biotechnology, 105, 1123-1131
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology 105 (2021)
Applied Microbiology and Biotechnology, 105 (3)

Many studies have established the functional properties of Lacticaseibacillus rhamnosus GG, previously known as Lactobacillus rhamnosus GG, marketed worldwide as a probiotic. The extraordinary capacity of L. rhamnosus GG to bind to human mucus and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c25c5d9e9a77ab1d13a369477e2989
https://doi.org/10.5167/uzh-213375