Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pia Ollikka"'
Publikováno v:
Bioconjugate Chemistry. 19:1269-1273
Four acyclic nucleoside triphosphates (derivatives of cytosine, thymine, 7-deazaadenine, and 7-deazaguanine) labeled with nonluminescent europium, terbium, dysprosium, and samarium chelates of 2,2',2'',2'''-[[4-(4-isothiocyanatophenyl)ethyl]pyridine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e030dca41acdfdb21099cb094faf047
https://doi.org/10.1021/bc800081n
https://doi.org/10.1021/bc800081n
Autor:
Ilkka Hemmilä, Pia Ollikka, Alice Ylikoski, Perttu Koskinen, Jaakko A. Puhakka, Katariina E.S. Tolvanen, Matti Karp
Publikováno v:
International Journal of Hydrogen Energy. 33:542-549
A quantitative real-time PCR (qrt-PCR) method was developed for quantification of a hydrogen-producing Clostridium butyricum strain. The strain was the main hydrogen producer in a mixed culture bioreactor that was operated on a continuous-flow mode f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28afdb44038d6fee648d5cc1e446a0e5
https://doi.org/10.1016/j.ijhydene.2007.10.005
https://doi.org/10.1016/j.ijhydene.2007.10.005
Autor:
Jari Hovinen, Pia Ollikka, Veli-Matti Mukkala, Annika Elomaa, Harri Hakala, Alice Ylikoski, Ilkka Hemmilä
Publikováno v:
Clinical Chemistry. 50:1943-1947
Laboratories performing genetic screening studies need simplified methods that allow automation for nucleic acid analysis. Ideally, a method should have as few handling steps as possible and allow the use of a closed-tube assay format to reduce the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6647ef4a24edcd40d17639da5a7469
https://doi.org/10.1373/clinchem.2004.036616
https://doi.org/10.1373/clinchem.2004.036616
Autor:
Harri Hakala, Pia Ollikka, Päivi Liitti, Jarkko Karvinen, Katri Puukka, Jari Peuralahti, Veli-Matti Mukkala, Alice Ylikoski, Kristiina Loman, Jari Hovinen
Publikováno v:
Inorganic Chemistry Communications. 5:1059-1062
A series of new stable, luminescent samarium(III) chelates were synthesized and their photophysical properties were measured. The iodoacetamido activated chelate coupled to a peptide was used in a caspase-3 assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8a5322334084e163786b4c7ac3350d
https://doi.org/10.1016/s1387-7003(02)00646-9
https://doi.org/10.1016/s1387-7003(02)00646-9
Publikováno v:
Tetrahedron. 58:8771-8777
Synthesis of two oligonucleotide building blocks based on acyclonucleosides (10, 11) which enable the introduction of several nonluminescent and luminescent lanthanide(III) chelates to the oligonucleotide structure is described. They were used in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57cad3ed4ac11e241abae277a296feba
https://doi.org/10.1016/s0040-4020(02)01056-6
https://doi.org/10.1016/s0040-4020(02)01056-6
Autor:
Pia Ollikka, Ville Laitala, Alice Ylikoski, Ilkka Hemmilä, Jari Hovinen, Lassi Jaakkola, Hanna-Mari Raussi
Publikováno v:
Analytical biochemistry. 386(1)
Expansion of molecular diagnostics more widely into clinical routines requires simplified methods allowing automation. We developed a homogeneous, multilabel polymerase chain reaction (PCR) method based on time-resolved fluorometry, and studied the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ff473519aa26f81bf2bc857c06ee8a
https://pubmed.ncbi.nlm.nih.gov/19111519
https://pubmed.ncbi.nlm.nih.gov/19111519
Publikováno v:
Analytical biochemistry. 361(1)
We report here an extension of homogeneous assays based on fluorescence intensity and lifetime measuring on DNA hybridization. A novel decay probe that allows simple one-step nucleic acid detection with subnanomolar sensitivity, and is suitable for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5b82dab9d208cbdfe8f8e32d94b294
https://pubmed.ncbi.nlm.nih.gov/17188225
https://pubmed.ncbi.nlm.nih.gov/17188225
Autor:
Heini Frang, Pertti Hurskainen, Rita Syystö, Ilkka Hemmilä, Veli-Matti Mukkala, Pia Ollikka, Mika Scheinin
Publikováno v:
Assay and drug development technologies. 1(2)
GPCRs represent important targets for drug discovery because GPCRs participate in a wide range of cellular signaling pathways that play a role in a variety of pathological conditions. A large number of screening assays have been developed in HTS labo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abf040b752df7282d6907494b3b23a6
https://pubmed.ncbi.nlm.nih.gov/15090192
https://pubmed.ncbi.nlm.nih.gov/15090192
Publikováno v:
Bioconjugate Chemistry; May2008, Vol. 19 Issue 6, p1269-1273, 5p
Autor:
Heini Frang, Veli-Matti Mukkala, Rita Syystö, Pia Ollikka, Pertti Hurskainen, Mika Scheinin, Ilkka Hemmilä
Publikováno v:
Assay & Drug Development Technologies; Apr2003, Vol. 1 Issue 2, p275-280, 6p