Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Pia Larsson"'
Autor:
Abigail S. McGovern, Pia Larsson, Volga Tarlac, Natasha Setiabakti, Leila Shabani Mashcool, Justin R. Hamilton, Niklas Boknäs, Juan Nunez-Iglesias
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
AbstractThe last decade has seen increasing use of advanced imaging techniques in platelet research. However, there has been a lag in the development of image analysis methods, leaving much of the information trapped in images. Herein, we present a r
Externí odkaz:
https://doaj.org/article/51906f3a1fa541c297ef889cc4fb0c1e
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Pharmacological inhibition of the platelet ADP-receptor P2Y12 is a cornerstone in the prevention of atherothrombotic events in adult patients with acute coronary syndrome (ACS). Thienopyridines such as clopidogrel and prasugrel exert their antithromb
Externí odkaz:
https://doaj.org/article/e760f2e4c67d4a47b645b869275587b4
Autor:
Maria Daglas, Dominik F. Draxler, Heidi Ho, Fiona McCutcheon, Adam Galle, Amanda E. Au, Pia Larsson, Julia Gregory, Frank Alderuccio, Maithili Sashindranath, Robert L. Medcalf
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1178-1191.e6 (2019)
Summary: Traumatic brain injury (TBI) leaves many survivors with long-term disabilities. A prolonged immune response in the brain may cause neurodegeneration, resulting in chronic neurological disturbances. In this study, using a TBI mouse model, we
Externí odkaz:
https://doaj.org/article/b8a4fd86be32435496abc3f41d48850c
Autor:
Be'eri Niego, Natasha Lee, Pia Larsson, T Michael De Silva, Amanda E-Ling Au, Fiona McCutcheon, Robert L Medcalf
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177332 (2017)
Rho-kinase (ROCK) inhibition, broadly utilised in cardiovascular disease, may protect the blood-brain barrier (BBB) during thrombolysis from rt-PA-induced damage. While the use of nonselective ROCK inhibitors like fasudil together with rt-PA may be h
Externí odkaz:
https://doaj.org/article/d73e582a17a8443a938ad38bf8af1d11
Autor:
Christian Brischke, Linda Meyer, Gry Alfredsen, Miha Humar, Lesley Francis, Per-Otto Flæte, Pia Larsson-Brelid
Publikováno v:
Drvna Industrija, Vol 64, Iss 2, Pp 113-129 (2013)
Besides its inherent resistance against degrading organisms, the durability of timber is influenced by design details and climatic conditions, making it difficult to treat wood durability as an absolute value. Durability classification is, therefore,
Externí odkaz:
https://doaj.org/article/a2d11c91191f4201b41085cc83355ff2
Publikováno v:
International Journal of Vascular Medicine, Vol 2016 (2016)
Objective. Endothelial tissue-type plasminogen activator (t-PA) release is a pivotal response to protect the circulation from occluding thrombosis. We have shown that the t-PA gene is epigenetically regulated and greatly induced by the histone deacet
Externí odkaz:
https://doaj.org/article/16b5854a967449539b07e055a5e4b269
Autor:
Kristina Svennerholm, Michael Haney, Björn Biber, Erik Ulfhammer, Ott Saluveer, Pia Larsson, Elmir Omerovic, Sverker Jern, Niklas Bergh
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128283 (2015)
Externí odkaz:
https://doaj.org/article/f2480fa4634247138fdb97a2f50ee931
Autor:
Mia Magnusson, Emma Xuchun Lu, Pia Larsson, Erik Ulfhammer, Niklas Bergh, Helena Carén, Sverker Jern
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141805 (2015)
Tissue-type plasminogen activator (t-PA), which is synthesized in the endothelial cells lining the blood vessel walls, is a key player in the fibrinolytic system protecting the circulation against occluding thrombus formation. Although classical gene
Externí odkaz:
https://doaj.org/article/166a4e10d025427590e1ba70a8675d2e
Autor:
Kristina Svennerholm, Michael Haney, Björn Biber, Erik Ulfhammer, Ott Saluveer, Pia Larsson, Elmir Omerovic, Sverker Jern, Niklas Bergh
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121196 (2015)
The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition. The study aimed to test if histone deacetalyase inhibitor treatment lead to increased t-PA
Externí odkaz:
https://doaj.org/article/381664977cd84508822470fc568d998c
Autor:
Ott Saluveer, Pia Larsson, Wilhelm Ridderstråle, Thórdís J Hrafnkelsdóttir, Sverker Jern, Niklas Bergh
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107582 (2014)
AIMS: The aim of the study was to test if pharmacological intervention by valproic acid (VPA) treatment can modulate the fibrinolytic system in man, by means of increased acute release capacity of tissue plasminogen activator (t-PA) as well as an alt
Externí odkaz:
https://doaj.org/article/ada22bdc6d11401c8664f55e50a90e3c