Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pia L. Graham"'
Autor:
Cathryn A. Shaw-Reid, James L. Cole, John S. Wai, Mark Embrey, Vandna Munshi, Marc V. Witmer, David B. Olsen, Abigail Wolfe, Daria J. Hazuda, Michael D. Miller, Steven S. Carroll, Pia L. Graham, Renee Danzeisen
Publikováno v:
Journal of Biological Chemistry. 278:2777-2780
Human immunodeficiency virus-type 1 (HIV-1) reverse transcriptase (RT) coordinates DNA polymerization and ribonuclease H (RNase H) activities using two discrete active sites embedded within a single heterodimeric polyprotein. We have identified a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b43a071f704cd525db0b745804d053
https://doi.org/10.1074/jbc.c200621200
https://doi.org/10.1074/jbc.c200621200
Autor:
Lucia Herranz, Joanne E. Tomassini, Pia L. Graham, Donette S. Quamina, Deborah L. Zink, Russell B. Lingham, Ziqiang Guan, Magda M. Gagliardi, Renee Danzeisen, Sheo B. Singh, Hiranthi Jayasuriya, Olga Genilloud
Publikováno v:
Journal of Natural Products. 65:1091-1095
Tat is a small HIV protein essential for both viral replication and the progression of HIV disease. In our efforts to discover Tat inhibitors from natural product screening of microbial fermentation extracts, we discovered durhamycin A (1) as a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6d6dc92c46fa5d6444d80442c15b5b
https://doi.org/10.1021/np010642f
https://doi.org/10.1021/np010642f
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:3143-3146
2-Methoxystypandrone, a naphthoquinone, was isolated from a Chinese herb Polygonum cuspidatum by bioassay guided fractionation using HRV 3C-protease assay. It showed an IC 50 value of 4.6 μM and is moderately selective. A new 10-step, total synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5721d3300f56ba6ef229a8730c9074e4
https://doi.org/10.1016/s0960-894x(01)00648-5
https://doi.org/10.1016/s0960-894x(01)00648-5
Autor:
J C Hastings, Robert L. Lafemina, Abigail Wolfe, Pia L. Graham, Emilio A. Emini, Daria J. Hazuda, H L Robbins
Publikováno v:
Journal of Biological Chemistry. 269:3999-4004
A DNA binding assay was developed for the human immunodeficiency virus type 1 (HIV-1) integrase. The assay was capable of defining discrete complexes between the enzyme and the viral long terminal repeat (LTR) substrate. DNA binding reflected the seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526a554cd34633ec28fc83569f5724d2
https://doi.org/10.1016/s0021-9258(17)41733-9
https://doi.org/10.1016/s0021-9258(17)41733-9
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98103092e8c937cdee485e510661f9b
https://doi.org/10.1002/chin.200211205
https://doi.org/10.1002/chin.200211205
Autor:
Olga Genilloud, Pia L. Graham, Anne W. Dombrowski, Lucia Herranz, Sheo B. Singh, Gerald F. Bills, Hiranthi Jayasuriya, Russell B. Lingham, Deborah L. Zink, Donette S. Quamina, Joanne E. Tomassini, Fernando Pelaez, Renee Danzeizen, Jon D. Polishook
Publikováno v:
Chemistrybiodiversity. 2(1)
HIV-1 Tat is one of six regulatory proteins that are required for viral replication and is an attractive target for the development of new anti-HIV agents. Screening of microbial extracts using a whole cell Tat-dependent transactivation assay, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8decfc00f30a557a01dfa6830894a9
https://pubmed.ncbi.nlm.nih.gov/17191924
https://pubmed.ncbi.nlm.nih.gov/17191924
Autor:
J C Hastings, K LeGrow, Daria J. Hazuda, Pia L. Graham, Emilio A. Emini, Abigail Wolfe, Robert L. Lafemina, Steven D. Young
The human immunodeficiency virus type 1 (HIV-1) integrase protein is required for the productive infection of T-lymphoid cells in culture (R. L. LaFemina, C. L. Schneider, H. L. Robbins, P. L. Callahan, K. LeGrow, E. Roth, W. A. Schleif, and E. A. Em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca5afab88fde0564ce80c40ba17e337
https://europepmc.org/articles/PMC162534/
https://europepmc.org/articles/PMC162534/
Autor:
Krista Getty, Pia L. Graham, E Boots, Lu Gan, Robert L. Lafemina, V Munshi, Bohdan S. Wolanski, John F. Fay, Joanne E. Tomassini
Publikováno v:
Virology. (1):274-285
We have established an in vitro replication system for bovine viral diarrhea virus (BVDV), a surrogate for the closely-related hepatitis C virus. In an in vitro reaction, BVDV replication complexes synthesize vRNA and replicative form (RF) and replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b8c29776bb786d82e931cdc22c0f5e