Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Pia D Vogel"'
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250371 (2021)
P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer's disease (AD). However, previous studies on the ability of P-gp to directly transport the Alzheimer's associated amyloid-β (Aβ
Externí odkaz:
https://doaj.org/article/d65591ac78d74ab7b49b37ad26f7cea9
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217940 (2019)
One common reason for cancer chemotherapy failure is increased drug efflux catalyzed by membrane transporters with broad pump substrate specificities, which leads to resistances to a wide range of chemically unrelated drugs. This multidrug resistance
Externí odkaz:
https://doaj.org/article/85d7256a0d574f3583a1a41897f6c7fd
Optimizing Targeted Inhibitors of P-Glycoprotein Using Computational and Structure-Guided Approaches
Autor:
Maha Aljowni, Pia D. Vogel, Gang Chen, John G. Wise, Amila K. Nanayakkara, Maisa C. Oliveira, Ketetha Olengue, Alexander R. Lippert, Lauren Ammerman
Publikováno v:
J Med Chem
Overexpression of ABC transporters like P-glycoprotein (P-gp) has been correlated with resistances in cancer chemotherapy. Intensive efforts to identify P-gp inhibitors for use in combination therapy have not led to clinically approved inhibitors to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df215630ba7076fcf2fba75f58deef2
https://doi.org/10.1021/acs.jmedchem.9b00966
https://doi.org/10.1021/acs.jmedchem.9b00966
Autor:
Pia D. Vogel, A. Dean Befus, David Rosenfield, Richard J. Auchus, Ana F. Trueba, Chris D. St. Laurent, Eduardo Reyes-Serratos, Chelsey A. Werchan, Thomas Ritz
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 312:R1004-R1016
Calcium-binding protein spermatid-specific 1 (CABS1) is expressed in the human submandibular gland and has an anti-inflammatory motif similar to that in submandibular rat 1 in rats. Here, we investigate CABS1 in human saliva and its association with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3ecda098e5ba1c7104d4c7b32984ba
https://doi.org/10.1152/ajpregu.00393.2016
https://doi.org/10.1152/ajpregu.00393.2016
Autor:
Alexander R. Lippert, John G. Wise, Maha Aljowni, Kasi L. Holcomb-Webb, Pia D. Vogel, Amila K. Nanayakkara
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8599e95f53557aa255fad3f3b320a645
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.11
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.11
Autor:
Pia D. Vogel, John G. Wise, Jennifer M. Edgar, Madeline K. Jensen, Maisa C. Olivera, Roxana Farokhnia, Dakota D. D. Okwuone
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ba241a00875a4ba51665c4ce6d0c9c4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.9
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.9
Autor:
John G. Wise, Maisa C. Oliveira, Roxana Farokhnia, Pia D. Vogel, Madeline K. Jensen, Jennifer M. Edgar, Dakota D. D. Okwuone
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8831e644d3ec28befed60d3d74e0262c
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.18
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.18
Autor:
Pia D. Vogel, Collette A. Lavigne, Dakota D. D. Okwuone, John G. Wise, Roxana Farokhnia, Jennifer M. Edgar, Maisa C. Oliveira, Madeline K. Jensen
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff0b100c32b4aaedc19a816f19c3896
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.13
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.13
Autor:
John G. Wise, Madeline K. Jensen, Maisa C. Oliveira, Dakota D. D. Okwuone, Pia D. Vogel, Roxana Farokhnia, Jennifer M. Edgar
Publikováno v:
The FASEB Journal. 33
P-glycoprotein (P-gp) overexpression is often correlated with multidrug-resistance (MDR) of cancer. To search for P-gp inhibitors as co-therapeutics to combat MDR, we had previously used high-throu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d029781130a97133d3cdbba6003bfba4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.20
https://doi.org/10.1096/fasebj.2019.33.1_supplement.782.20
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250371 (2021)
PLoS ONE
PLoS ONE
P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer’s disease (AD). However, previous studies on the ability of P-gp to directly transport the Alzheimer’s associated amyloid-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3255e8da651bbac90fa7ab460e5d9
https://doi.org/10.1371/journal.pone.0250371
https://doi.org/10.1371/journal.pone.0250371