Functional annotation of proteins for signaling network inference in non-model species

Autor: Lisa Van den Broeck, Dinesh Kiran Bhosale, Kuncheng Song, Cássio Flavio Fonseca de Lima, Michael Ashley, Tingting Zhu, Shanshuo Zhu, Brigitte Van De Cotte, Pia Neyt, Anna C. Ortiz, Tiffany R. Sikes, Jonas Aper, Peter Lootens, Anna M. Locke, Ive De Smet, Rosangela Sozzani

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Abstract Molecular biology aims to understand cellular responses and regulatory dynamics in complex biological systems. However, these studies remain challenging in non-model species due to poor functional annotation of regulatory proteins. To overco

Externí odkaz: https://doaj.org/article/d4b2817c52f34a10ac17fd0675610d4d

Histone 2B monoubiquitination complex integrates transcript elongation with RNA processing at circadian clock and flowering regulators

Autor: Geert De Jaeger, Magdalena Woloszynska, Klaus D. Grasser, Stijn Dhondt, Gernot Längst, Tommaso Matteo Boccardi, Sabine Le Gall, Marion Grasser, Eveline Van De Slijke, Maria Van Lijsebettens, Leonardo Bruno, Griet Coussens, Jorge Fung-Uceda, Dirk Inzé, Paloma Mas, Stijn Aesaert, Pia Neyt, Kristiina Himanen, Marc Van Montagu

Publikováno v: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Digital.CSIC. Repositorio Institucional del CSIC
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Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

HISTONE MONOUBIQUITINATION1 (HUB1) and its paralog HUB2 act in a conserved heterotetrameric complex in the chromatin-mediated transcriptional modulation of developmental programs, such as flowering time, dormancy, and the circadian clock. The KHD1 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7f95af03bbd58ff27dd65053768f94
https://pubmed.ncbi.nlm.nih.gov/30923114

ROTUNDA3 function in plant development by phosphatase 2A-mediated regulation of auxin transporter recycling

Autor: Nancy De Winne, Stijn Aesaert, Geert De Jaeger, María Rosa Ponce, Jiří Friml, Annemie Van Minnebruggen, Pia Neyt, Leonardo Bruno, Griet Coussens, Michael Karampelias, José Luis Micol, Marc Van Montagu, Steven De Groeve, Jakub Rolčík, Mieke Van Lijsebettens

Publikováno v: Proceedings of the National Academy of Sciences. 113:2768-2773

The shaping of organs in plants depends on the intercellular flow of the phytohormone auxin, of which the directional signaling is determined by the polar subcellular localization of PIN-FORMED (PIN) auxin transport proteins. Phosphorylation dynamics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502584085fdea66d4d035bfc66feba14
https://doi.org/10.1073/pnas.1501343112

The Elongator complex regulates hypocotyl growth in darkness and during photomorphogenesis

Autor: Magdalena, Woloszynska, Olimpia, Gagliardi, Filip, Vandenbussche, Steven, De Groeve, Luis, Alonso Baez, Pia, Neyt, Sabine, Le Gall, Jorge, Fung, Paloma, Mas, Dominique, Van Der Straeten, Mieke, Van Lijsebettens

Publikováno v: Journal of cell science. 131(2)

The Elongator complex (hereafter Elongator) promotes RNA polymerase II-mediated transcript elongation through epigenetic activities such as histone acetylation. Elongator regulates growth, development, immune response and sensitivity to drought and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4cf17c08478144d09bdb042e075bd0ec
https://pubmed.ncbi.nlm.nih.gov/28720596

The ang3 mutation identified the ribosomal protein gene RPL5B with a role in cell expansion during organ growth

Autor: Mieke Van Lijsebettens, Annemie Van Minnebruggen, Griet Coussens, Steven De Groeve, María Rosa Ponce, Pia Neyt, José Luis Micol

Publikováno v: Physiologia Plantarum. 138:91-101

The role of translation in the regulation of higher plant growth and development is not well understood. Mutational analysis is a powerful tool to identify and study the function of genes related to a biological process, such as growth. Here we analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf89ed6ae1443d78ba482113d6fbb5d
https://doi.org/10.1111/j.1399-3054.2009.01301.x