Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Pi-jing Wei"'
Publikováno v:
Biology, Vol 13, Iss 3, p 184 (2024)
Cancer is a complex and evolutionary disease mainly driven by the accumulation of genetic variations in genes. Identifying cancer driver genes is important. However, most related studies have focused on the population level. Cancer is a disease with
Externí odkaz:
https://doaj.org/article/81f21a3db17b4e77a9385f6ed67be66d
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S3, Pp 1-16 (2021)
Abstract Background As one of the deadliest diseases in the world, cancer is driven by a few somatic mutations that disrupt the normal growth of cells, and leads to abnormal proliferation and tumor development. The vast majority of somatic mutations
Externí odkaz:
https://doaj.org/article/3c8bbb5747a4471bb5081cefd51baa78
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Circular RNAs (circRNAs) are a class of single-stranded RNA molecules with a closed-loop structure. A growing body of research has shown that circRNAs are closely related to the development of diseases. Because biological experime
Externí odkaz:
https://doaj.org/article/702cf44c844a4f588db16ef9fe819001
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S7, Pp 1-10 (2019)
Abstract Background Although there are huge volumes of genomic data, how to decipher them and identify driver events is still a challenge. The current methods based on network typically use the relationship between genomic events and consequent chang
Externí odkaz:
https://doaj.org/article/f4f66709c2434671ae31c355cb73348a
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Identifying driver genes that contribute to cancer progression from numerous passenger genes, although a central goal, is a major challenge. The protein–protein interaction network provides convenient and reasonable assistance for driver gene disco
Externí odkaz:
https://doaj.org/article/5c44b7b62c58432c8158cb839e6b489d
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Complex diseases are known to be associated with disease genes. Uncovering disease-gene associations is critical for diagnosis, treatment, and prevention of diseases. Computational algorithms which effectively predict candidate disease-gene associati
Externí odkaz:
https://doaj.org/article/3b6200356a6741cf9fe5c24cb4b27218
Publikováno v:
Complexity, Vol 2017 (2017)
Integration of multi-omics data of cancer can help people to explore cancers comprehensively. However, with a large volume of different omics and functional data being generated, there is a major challenge to distinguish functional driver genes from
Externí odkaz:
https://doaj.org/article/60376390fe6c46bfa079bb20c5d10b23
Publikováno v:
Methods. 213:42-49
Publikováno v:
Methods. 204:38-46
Promoter is a key DNA element located near the transcription start site, which regulates gene transcription by binding RNA polymerase. Thus, the identification of promoters is an important research field in synthetic biology. Nannochloropsis is an im
Publikováno v:
Computer methods and programs in biomedicine. 226
The promoter is a fragment of DNA and a specific sequence with transcriptional regulation function in DNA. Promoters are located upstream at the transcription start site, which is used to initiate downstream gene expression. So far, promoter identifi