Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Phyllis X.L. Gan"'
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106929- (2023)
Severe asthma is a difficult-to-treat chronic airway inflammatory disease requiring systemic corticosteroids to achieve asthma control. It has recently been shown that drugs targeting immunometabolism have elicited anti-inflammatory effects. The purp
Externí odkaz:
https://doaj.org/article/b9c3115bd4734d8cb7e24b8d175da919
Autor:
Quy T.N. Tran, Phyllis X.L. Gan, Wupeng Liao, Yu Keung Mok, Christina L.L. Chai, W.S. Fred Wong
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106861- (2023)
The p38MAPK-MK2 signaling axis functions as an initiator of inflammation. Targeting the p38MAPK-MK2 signaling axis represents a direct therapeutic intervention of inflammatory diseases. We described here a novel role of andrographolide (AG), a small-
Externí odkaz:
https://doaj.org/article/fc9e6c19302c4d7f9cff817171450cde
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 6, Pp 1305-1319 (2021)
Approximately 25% to 40% of patients with chronic obstructive pulmonary disease (COPD) have the eosinophilic endotype. It is important to identify this group accurately because they are more symptomatic and are at increased risk for exacerbations and
Externí odkaz:
https://doaj.org/article/73dee75f007948f68c61dda89afb3cae
Autor:
Dan Mei, Wupeng Liao, Phyllis X.L. Gan, Quy T.N. Tran, Christabel C.M.Y. Chan, C.K. Matthew Heng, W.S. Fred Wong
Publikováno v:
Pharmacological research. 184
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally. Cumulative evidence has implicated renin-angiotensin system (RAS) in the pathogenesis of COPD. Alveolar macrophages (AMs) are the first line immune defense in