SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling

Autor: Gwyndolen Harburg, Jennifer Compton, Wei Liu, Naomi Iwai, Shahrzad Zada, Rebecca Marlow, Phyllis Strickland, Yi Arial Zeng, Lindsay Hinck

Publikováno v: Stem Cell Reports, Vol 3, Iss 3, Pp 385-393 (2014)

WNT signaling stimulates the self-renewal of many types of adult stem cells, including mammary stem cells (MaSCs), but mechanisms that limit this activity are poorly understood. Here, we demonstrate that SLIT2 restricts stem cell renewal by signaling

Externí odkaz: https://doaj.org/article/1259f5beb3c14a56988bd0fb05d79744

Supplementary Figure 6 from SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Autor: Lindsay Hinck, Saraswati Sukumar, Robert D. Cardiff, Hector Macias, Angel Moran, Elizabeth K. Le, Mikhail Binnewies, Milana PeBenito, Xinyan Wu, Ji Shin Lee, Phyllis Strickland, Rebecca Marlow

Supplementary Figure 6 from SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f22e785adbdc2d30ece6344fd62c74c
https://doi.org/10.1158/0008-5472.22375832.v1

Supplementary Figure Legends 1-6 from SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Autor: Lindsay Hinck, Saraswati Sukumar, Robert D. Cardiff, Hector Macias, Angel Moran, Elizabeth K. Le, Mikhail Binnewies, Milana PeBenito, Xinyan Wu, Ji Shin Lee, Phyllis Strickland, Rebecca Marlow

Supplementary Figure Legends 1-6 from SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ca75f4dedc8cd28dd7074b38c50eb1
https://doi.org/10.1158/0008-5472.22375829

SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling

Autor: Shahrzad Zada, Lindsay Hinck, Rebecca Marlow, Jennifer E. Compton, Naomi Iwai, Yi Arial Zeng, Wei Liu, Gwyndolen Harburg, Phyllis Strickland

Publikováno v: Stem Cell Reports, Vol 3, Iss 3, Pp 385-393 (2014)
Stem Cell Reports
Stem cell reports, vol 3, iss 3
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/6p50215s
Harburg, G; Compton, J; Liu, W; Iwai, N; Zada, S; Marlow, R; et al.(2014). SLIT/ROBO2 signaling promotes mammary stem cell senescence by inhibiting wnt signaling. Stem Cell Reports, 3(3), 385-393. doi: 10.1016/j.stemcr.2014.07.007. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/84q569vd
Stem Cell Reports, vol 3, iss 3

Summary WNT signaling stimulates the self-renewal of many types of adult stem cells, including mammary stem cells (MaSCs), but mechanisms that limit this activity are poorly understood. Here, we demonstrate that SLIT2 restricts stem cell renewal by s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442f4296e178a305ca2add7d3b6e6525

Netrin-1/Neogenin Interaction Stabilizes Multipotent Progenitor Cap Cells during Mammary Gland Morphogenesis

Autor: Karpagam Srinivasan, Grace C. Shin, Phyllis Strickland, Lindsay Hinck, Ana Valdes

Publikováno v: Developmental Cell. 4:371-382

Netrin-1 and its receptors play an essential role patterning the nervous system by guiding neurons and axons to their targets. To explore whether netrin-1 organizes nonneural tissues, we examined its role in mammary gland morphogenesis. Netrin-1 is e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afaab39793186309b83408dc96e2cf1
https://doi.org/10.1016/s1534-5807(03)00054-6