Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Phyllis L. Faust"'
Autor:
Phyllis L. Faust, Morgan McCreary, Jessica B. Musacchio, Sheng‐Han Kuo, Jean‐Paul G. Vonsattel, Elan D. Louis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1514-1525 (2024)
Abstract Objective Essential tremor is among the most prevalent neurological diseases. Diagnosis is based entirely on neurological evaluation. Historically, there were few postmortem brain studies, hindering attempts to develop pathologically based c
Externí odkaz:
https://doaj.org/article/5353d20904244e67b26866e99499ea9e
Autor:
David S. Ruff, Ilaria Balbo, Ruo‐Yah Lai, Diarra Dieng, Charlotte Hennessey, Krish Vennam, Andrew J. Dwork, Morgan McCreary, Elan D. Louis, Phyllis L. Faust, Sheng‐Han Kuo
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 377-388 (2024)
Abstract Objective Postmortem examination of the essential tremor cerebellum has revealed a variety of pathological changes centered in and around Purkinje cells. Studies have predominantly focused on cerebellar neuronal connections. Bergmann glial m
Externí odkaz:
https://doaj.org/article/4b5a027e77934becaa5a906e6df8f236
Autor:
Chi‐Ying R. Lin, Anisha Viswanathan, Tiffany X. Chen, Hiroshi Mitsumoto, Jean P. Vonsattel, Phyllis L. Faust, Sheng‐Han Kuo
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 7, Pp 988-994 (2022)
Abstract Objective Pyramidal signs are common but often under‐recognized in multiple system atrophy (MSA). The clinicopathological correlates of pyramidal signs in MSA are not well characterized. The present study aims to understand the role of pyr
Externí odkaz:
https://doaj.org/article/847b6d83735646e087c11d12339b7083
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Huntington disease is characterized by progressive neurodegeneration, especially of the striatum, and the presence of polyglutamine huntingtin (HTT) inclusions. Although HTT inclusions are most abundant in the neocortex, their neocortical di
Externí odkaz:
https://doaj.org/article/f87e56b918344df688242c3ea8afbe7c
Autor:
Daneck Lang-Ouellette, Kim M. Gruver, Amy Smith-Dijak, François G. C. Blot, Chloe A. Stewart, Pauline de Vanssay de Blavous, Connie H. Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L. Faust, Martijn Schonewille, Alanna J. Watt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Axonal swellings have been found on Purkinje cell axons in the cerebellum both during development and disease. The authors show that axons with swellings propagate action potentials with higher fidelity than those without and that mice with more axon
Externí odkaz:
https://doaj.org/article/ea0d8880874746698230d5c079b876ee
Autor:
Osama Al-Dalahmah, Kiran T. Thakur, Anna S. Nordvig, Morgan L. Prust, William Roth, Angela Lignelli, Anne-Catrin Uhlemann, Emily Happy Miller, Shajo Kunnath-Velayudhan, Armando Del Portillo, Yang Liu, Gunnar Hargus, Andrew F. Teich, Richard A. Hickman, Kurenai Tanji, James E. Goldman, Phyllis L. Faust, Peter Canoll
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-7 (2020)
Abstract We document the neuropathologic findings of a 73-year old man who died from acute cerebellar hemorrhage in the context of relatively mild SARS-CoV2 infection. The patient developed sudden onset of headache, nausea, and vomiting, immediately
Externí odkaz:
https://doaj.org/article/49cc39dc32d249feb8e72859604afdfd
Autor:
Khanichi N. Charles, Janis E. Shackelford, Phyllis L. Faust, Steven J. Fliesler, Herbert Stangl, Werner J. Kovacs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. Cells adjust their sterol content by both transcriptional and post-transcriptional feedback regulation, for which sterol regulatory el
Externí odkaz:
https://doaj.org/article/f0eb6466aaf148c3937de0abf3ce0f21
Autor:
Tanja Eberhart, Miriam J. Schönenberger, Katharina M. Walter, Khanichi N. Charles, Phyllis L. Faust, Werner J. Kovacs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Ketohexokinase (KHK) is the first and rate-limiting enzyme of fructose metabolism. Expression of the two alternatively spliced KHK isoforms, KHK-A and KHK-C, is tissue-specific and KHK-C is predominantly expressed in liver, kidney and intestine and r
Externí odkaz:
https://doaj.org/article/5912013fb27c4b769f23799730e58776
Autor:
Stephanie S. L. Cheung, Larissa K. Ghadiali, Thomas H. Brannagan III, Gul Moonis, Phyllis L. Faust, Jeffrey G. Odel
Publikováno v:
Case Reports in Ophthalmological Medicine, Vol 2017 (2017)
A 78-year-old woman complained of gradual, painless onset of horizontal binocular diplopia associated with progressive axial weakness. Physical examination revealed esotropia that was greater at distance than at near vision, bilateral levator dehisce
Externí odkaz:
https://doaj.org/article/0ddb4c4b024249c5851b2485c1194897
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2139-2147 (2009)
It is well established that peroxisomes play a crucial role in de novo bile acid synthesis. Studies in patients with a peroxisomal disorder have been indispensable for the elucidation of the precise role of peroxisomes. Several peroxisomal disorders
Externí odkaz:
https://doaj.org/article/c9930892d08d493f995c0cd6ffbe84cf