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pro vyhledávání: '"Phyllis K. Sher"'
Autor:
Phyllis K. Sher, Stuart B. Brown
Publikováno v:
Developmental Medicine & Child Neurology. 17:705-710
SUMMARY The early detection of progressive hydrocephalus in pre-term infants often is a difficult diagnostic problem. In this study, 43 pre-term infants with birthweights between 1000 and 2000g were examined shortly after birth and an estimate of ges
Autor:
Phyllis K. Sher, Shuxian Hu
Publikováno v:
Neuroscience. 47:979-984
The present study was undertaken to investigate the comparative effects of rapid vs graded correction of chronic hypoxia in vitro. Cerebral cortical cell cultures obtained from fetal mice were exposed to 5% O2 for 24 h and returned immediately to roo
Autor:
Phyllis K. Sher, Shuxian Hu
Publikováno v:
Brain Research Bulletin. 25:697-701
Whether there is preferential loss of certain types of nerve cells or specific cellular functions after hypoxic or ischemic insults remains unclear. To evaluate this phenomenon in vitro, the vulnerability of GABAergic neurons to hypoxia was investiga
Autor:
Phyllis K. Sher, Shuxian Hu
Publikováno v:
Glia. 3:350-357
To examine the neurochemical effects of chronic hypoxia on immature nervous tissue in vitro, mixed neuronal-glial cell cultures derived from fetal mice were exposed to 5% O2 for 24 or 48 h. Those cultures subjected to longer hypoxia manifested improv
Autor:
Phyllis K. Sher
Publikováno v:
Brain and Development. 12:293-300
Cerebral cortical cell cultures obtained from fetal mice were subjected to 5% O2 for 24 h at a developmental stage equivalent to that of the human neonate. Immediately after the hypoxic insult (HI), medium lactate was elevated and pH, partial pressur
Autor:
Phyllis K. Sher, Yuri Reinberg
Publikováno v:
The Journal of urology. 156(2 Pt 2)
Purpose: Giggle incontinence, the second most common type of childhood enuresis unrelated to disease, is notoriously difficult to treat. However, the association of laughter or emotion precipitated alteration of muscle tone is suggestive of a functio
Publikováno v:
Epilepsia. 35(6)
Summary: Carbamazepine (CBZ) has been reported to exacerbate some seizure types in children. We studied the correlation between CBZ-associated EEG changes and seizure exacerbation in 59 children aged
Autor:
Phyllis K. Sher, Muhammed R. Sheikh
Publikováno v:
Pediatric neurology. 9(6)
The records of twenty-six infants with both symptomatic infantile spasms and classic hypsarrhythmia were reviewed to determine the efficacy of various ACTH dosages and time of initiation of therapy. Mean age of infantile spasm onset was 6.4 months. M
Autor:
Phyllis K. Sher
Publikováno v:
Pediatric neurology. 7(6)
The relative efficacy of competitive and noncompetitive excitatory amino acid antagonists in preventing hypoxic neuronal injury recently was examined in vitro. Immature (26 days post-conception) fetal mouse cerebral cortical cell cultures were expose
Autor:
Phyllis K. Sher
Publikováno v:
Experimental neurology. 107(3)
Neuropathologic changes associated with perinatal hypoxic-ischemic events in the human infant most often result from chronic hypoxia rather than from acute asphyxia. To characterize the effects of acidosis associated with chronic hypoxia in developin