Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Phyllis Gardner"'
Autor:
Juan Rodriguez-Paris, Lynn Pique, Tahl Colen, Joseph Roberson, Phyllis Gardner, Iris Schrijver
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11804 (2010)
Molecular diagnostic testing of individuals with congenital sensorineural hearing loss typically begins with DNA sequencing of the GJB2 gene. If the cause of the hearing loss is not identified in GJB2, additional testing can be ordered. However, the
Externí odkaz:
https://doaj.org/article/37e9af9c86dc43c2891b65ab7df33e06
Publikováno v:
Experimental Cell Research. 315:1683-1692
Mutations in the genes that encode Connexin 26 (GJB2) and Connexin 30 (GJB6) are the most common known cause of hereditary nonsyndromic sensorineural deafness. Cx26 and Cx30 share a similar protein structure, as well as the same expression distributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41647fea2ddff281893d9274492321cd
https://doi.org/10.1016/j.yexcr.2009.03.001
https://doi.org/10.1016/j.yexcr.2009.03.001
Microfabricated nanochannel implantable drug delivery devices: trends, limitations and possibilities
Autor:
Phyllis Gardner
Publikováno v:
Expert Opinion on Drug Delivery. 3:479-487
This is a review of the application of microfabrication technologies, borrowed from the semiconductor industry, to drug delivery implants incorporating structures in the nanometer dimension. In the futuristic ideal, these systems would involve the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385dfe3924013ffa3aad43f31872a452
https://doi.org/10.1517/17425247.3.4.479
https://doi.org/10.1517/17425247.3.4.479
Autor:
Phyllis Gardner, Iris Schrijver
Publikováno v:
Expert Review of Molecular Diagnostics. 6:375-386
Hearing loss has a genetic etiology in the majority of cases and is very common. The universal newborn hearing screening program, together with remarkable recent progress in the characterization of genes associated with the function of hearing, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43cdaa3ef687357930affc5655c2b24
https://doi.org/10.1586/14737159.6.3.375
https://doi.org/10.1586/14737159.6.3.375
Publikováno v:
The Journal of Molecular Diagnostics. 7:375-387
Cystic fibrosis (CF), which is due to mutations in the cystic fibrosis transmembrane conductance regulator gene, is a common life-shortening disease. Although CF occurs with the highest incidence in Caucasians, it also occurs in other ethnicities wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f297219392a19a51f39eaea6a65dfc77
https://doi.org/10.1016/s1525-1578(10)60567-3
https://doi.org/10.1016/s1525-1578(10)60567-3
Autor:
Iris Schrijver, John Oehlert, Richard B. Moss, Steve Swanson, Anja Kammesheidt, Phyllis Gardner, Steven Keiles, Ramalingam Sankaran, Sudha Ramalingam, Charles Dunlop, E. Robert Wassman
Publikováno v:
The Journal of Molecular Diagnostics. 7:289-299
Characterization of CFTR mutations in the U.S. Hispanic population is vital to early diagnosis, genetic counseling, patient-specific treatment, and the understanding of cystic fibrosis (CF) pathogenesis. The mutation spectrum in Hispanics, however, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::823d374a3c58ea0e706cbd68e37f8c00
https://doi.org/10.1016/s1525-1578(10)60557-0
https://doi.org/10.1016/s1525-1578(10)60557-0
Autor:
Yun Ping Lim, Jan Olov Höög, Phyllis Gardner, Subramanian Subbiah, Siv G. E. Andersson, Tin Wee Tan, Anthony S. Weiss, Shoba Ranganathan, Winston Hide
Publikováno v:
Biochemistry and Molecular Biology Education. 31:20-23
The S-Star Trial Bioinformatics on-line course (www.s-star.org) is a global experiment in bioinformatics distance education. Six universities from five continents have participated in this project. One hundred and fifty students participated in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9e541a6aac406a1d34631315dce8b9
https://doi.org/10.1002/bmb.2003.494031010160
https://doi.org/10.1002/bmb.2003.494031010160
Autor:
William B. Guggino, Carol Conrad, Jeffrey J. Wine, Eric P. Batson, Richard B. Moss, Ilynn B. Nepomuceno, Barrie J. Carter, Julie K. Desch, Terence R. Flotte, Byron W. Brown, Anna H. Messner, Sue Dimiceli, John A. Wagner, Alexander Norbash, Thomas C. Reynolds, Mary Lynn Moran, Phyllis Gardner
Publikováno v:
Human Gene Therapy. 13:1349-1359
tgAAVCF, an adeno-associated cystic fibrosis transmembrane conductance regulator (CFTR) viral vector/gene construct, was administered to 23 patients in a Phase II, double-blind, randomized, placebo-controlled clinical trial. For each patient, a dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f30e0b6bacb49df80f55a45dfcbe4fd
https://doi.org/10.1089/104303402760128577
https://doi.org/10.1089/104303402760128577
Autor:
Keisuke Kouyama, Richard B. Moss, Terence R. Flotte, Thomas Reynolds, Julie K. Desch, Anna H. Messner, Mary Lynn Moran, Sara A. Manley, Phyllis Gardner, Jeffrey J. Wine, Carol Conrad, Richard Daifuku, Sandra Friborg, John A. Wagner, Alexander Norbash, Barrie J. Carter, William B. Guggino
Publikováno v:
The Laryngoscope. 109:266-274
Objective The host immune response and low vector efficiency have been key impediments to effective cystic fibrosis transmembrane regulator (CFTR) gene transfer for cystic fibrosis (CF). An adeno-associated virus vector (AAV-CFTR) was used in a phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d740c79a5bbe61585bc9ef49713320
https://doi.org/10.1097/00005537-199902000-00017
https://doi.org/10.1097/00005537-199902000-00017
Autor:
Jeffrey J. Wine, Ilynn B. Nepomuceno, Richard B. Moss, Anna H. Messner, Mary Lynn Moran, Phyllis Gardner, John A. Wagner, Alexander Norbash, Niraj Shah
Publikováno v:
The Journal of Gene Medicine. 1:13-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c011338d3b36eab02f77b074df5269ed
https://doi.org/10.1002/(sici)1521-2254(199901/02)1:1<13::aid-jgm6>3.0.co
https://doi.org/10.1002/(sici)1521-2254(199901/02)1:1<13::aid-jgm6>3.0.co