Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Phyllis C. Pugh"'
Autor:
Phyllis C Pugh, Elena W Adlaf, Chaunsheng eZhao, Sean J Markwardt, Cristin F Gavin, Jacques I Wadiche, Linda eOverstreet-Wadiche
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
The production and integration of adult-generated neurons in the dentate gyrus is dramatically perturbed by a variety of pathological insults, including repetitive seizures and hypoxia/ischemia. Less is known about how insults affect early postnatal
Externí odkaz:
https://doaj.org/article/fb21aaca1e7c4f32aa80c87dd31cb5f4
Autor:
Phyllis C. Pugh, Matthew E. Glover, Huda Akil, Sarah M. Clinton, Joshua L. Cohen, Rebecca K. Simmons, Ilan A. Kerman, Andrew D. Fant
Publikováno v:
Developmental Neuroscience. 37:203-214
The early-life environment critically influences neurodevelopment and later psychological health. To elucidate neural and environmental elements that shape emotional behavior, we developed a rat model of individual differences in temperament and envi
Autor:
Phyllis C. Pugh, Dailey Nettles, Linda Overstreet-Wadiche, Ann M. Laszczyk, Stephanie Fox-Quick, Gwendalyn D. King, Hai T. Vo
Publikováno v:
Neurobiology of aging. 59
Although the absence of the age-regulating klotho protein causes klotho-deficient mice to rapidly develop cognitive impairment and increasing klotho enhances hippocampal-dependent memory, the cellular effects of klotho that mediate hippocampal-depend
Autor:
Selwyn S. Jayakar, Samantha Cole, Eric R. Starr, Zack Dale, Joseph F. Margiotta, Phyllis C. Pugh
Publikováno v:
Molecular and Cellular Neuroscience. 63:1-12
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide found at synapses throughout the central and autonomic nervous system. We previously found that PACAP engages a selective G-protein coupled receptor (PAC1R) on c
Autor:
Elena W Adlaf, Phyllis C. Pugh, Jessica H. Chancey, Matthew C. Sapp, Jacques I. Wadiche, Linda Overstreet-Wadiche
Publikováno v:
The Journal of Neuroscience. 33:6614-6622
Neural activity enhances adult neurogenesis, enabling experience to influence the construction of new circuits. GABAAreceptor-mediated depolarization of newborn neurons in the adult and developing brain promotes glutamatergic synaptic integration sin
Autor:
Tamas Kozicz, Najmul S. Shah, Balázs Gaszner, Devin T. Rosenthal, Hyungwoo Nam, Ilan A. Kerman, Phyllis C. Pugh, Diane C.W.A. van Wijk
Publikováno v:
Journal of Chemical Neuroanatomy, 52, pp. 25-35
Journal of Chemical Neuroanatomy, 52, 25-35
Journal of Chemical Neuroanatomy, 52, 25-35
Contains fulltext : 119290.pdf (Publisher’s version ) (Closed access) Numerous motivated behaviors require simultaneous activation of somatomotor and autonomic functions. We have previously characterized the organization of brain circuits that may
Autor:
Ilan A. Kerman, Samir Rana, Sara A. Stringfellow, Harald M. Stauss, C. Roger White, Sarah M. Clinton, Phyllis C. Pugh, Erin Katz, Chee Paul Lin, J. Michael Wyss
Early-life experience (ELE) can significantly affect life-long health and disease, including cardiovascular function. Specific dimensions of emotionality also modify risk of disease, and aggressive traits along with social inhibition have been establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc398ae4e5924931006a836c74f154ed
https://europepmc.org/articles/PMC5008659/
https://europepmc.org/articles/PMC5008659/
Publikováno v:
Molecular and Cellular Neuroscience. 43:244-257
Neuropeptides collaborate with conventional neurotransmitters to regulate synaptic output. Pituitary adenylate cyclase-activating polypeptide (PACAP) co-localizes with acetylcholine in presynaptic nerve terminals, is released by stimulation, and enha
Autor:
J. Michael Wyss, Phyllis C. Pugh, Sara A. Stringfellow, Roger White, Harald M. Stauss, Ilan A. Kerman, Samir Rana
Publikováno v:
The FASEB Journal. 29
Classical studies have implicated specific personality traits as predictive of adverse cardiovascular function, yet biological mechanisms that contribute to such associations remain elusive. We inv...
Autor:
Chelsea R. McCoy, Sarah M. Clinton, Phyllis C. Pugh, J. Michael Wyss, Ilan A. Kerman, Samir Rana
Publikováno v:
The FASEB Journal. 29
Early-life experiences can have long-term effects on cardiovascular function and are likely mediated by a host of factors, such as inborn stress sensitivity and epigenetic alterations. To begin addressing this issue we exposed Wistar-Kyoto (WKY) rats