Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Phyllis A Gimotty"'
Autor:
Malay K. Sannigrahi, Austin C. Cao, Pavithra Rajagopalan, Lova Sun, Robert M. Brody, Lovely Raghav, Phyllis A. Gimotty, Devraj Basu
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 336-349 (2024)
There is limited guidance on exploiting the genome‐wide loss‐of‐function CRISPR screens in cancer Dependency Map (DepMap) to identify new targets for individual cancer types. This study integrated multiple tools to filter these data in order to
Externí odkaz:
https://doaj.org/article/5a52bfb1fc6c4551869e5a8296b1e1e4
Autor:
Carissa J. Norquest, Anita Rogic, Phyllis A. Gimotty, Charles A. Maitz, Hansjorg Rindt, Hayley L. Ashworth, Jeffrey N. Bryan, Lindsay L. Donnelly, Angela L. McCleary-Wheeler, Brian K. Flesner
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionZoledronic acid (ZOL) is a third-generation bisphosphonate with a higher affinity for bone resorption areas than earlier bisphosphonates (i.e., pamidronate, PAM). In human medicine, ZOL provides improved bone pain relief and prolonged tim
Externí odkaz:
https://doaj.org/article/bde0331aac46404291b83e663e3169b2
Autor:
Susan E. McClory, Oishi Bardhan, Kelly S. Rome, Josephine R. Giles, Amy E. Baxter, Lanwei Xu, Phyllis A. Gimotty, Robert B. Faryabi, E. John Wherry, Warren S. Pear, Martha S. Jordan
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112905- (2023)
Summary: CD8+ T cell exhaustion (TEX) impairs the ability of T cells to clear chronic infection or cancer. While TEX are hypofunctional, some TEX retain effector gene signatures, a feature associated with killer lectin-like receptor (KLR) expression.
Externí odkaz:
https://doaj.org/article/649d5307b00c4acca7e424a01f75bf3e
Autor:
Gaurav Sharma, Rani Ojha, Estela Noguera-Ortega, Vito W. Rebecca, John Attanasio, Shujing Liu, Shengfu Piao, Jennifer J. Lee, Michael C. Nicastri, Sandra L. Harper, Amruta Ronghe, Vaibhav Jain, Jeffrey D. Winkler, David W. Speicher, Jerome Mastio, Phyllis A. Gimotty, Xiaowei Xu, E. John Wherry, Dmitry I. Gabrilovich, Ravi K. Amaravadi
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
Externí odkaz:
https://doaj.org/article/643236f5ac4b4d019428d52c84e9657d
Autor:
Malay K. Sannigrahi, Pavithra Rajagopalan, Ling Lai, Xinyi Liu, Varun Sahu, Hiroshi Nakagawa, Jalal B. Jalaly, Robert M. Brody, Iain M. Morgan, Bradford E. Windle, Xiaowei Wang, Phyllis A. Gimotty, Daniel P. Kelly, Elizabeth A. White, Devraj Basu
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Therapy with radiation plus cisplatin kills HPV+ oropharyngeal squamous cell carcinomas (OPSCCs) by increasing reactive oxygen species beyond cellular antioxidant capacity. To explore why these standard treatments fail for some patients, we evaluated
Externí odkaz:
https://doaj.org/article/2e2a2366ebb445348cb086698c1327da
Autor:
Nicholas P. McAndrew, Lisa Bottalico, Clementina Mesaros, Ian A. Blair, Patricia Y. Tsao, Jennifer M. Rosado, Tapan Ganguly, Sarah J. Song, Phyllis A. Gimotty, Jun J. Mao, Angela DeMichele
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Chronic inflammation has been a proposed mechanism of resistance to aromatase inhibitors in breast cancer. Stratifying by HER2 status, a matched case-control study from the Wellness After Breast Cancer-II cohort was performed to assess wheth
Externí odkaz:
https://doaj.org/article/c1797f3e22424ecda689fbfd30194490
Autor:
Cimarron E, Sharon, Richard J, Straker, Phyllis A, Gimotty, Emily Y, Chu, Tara C, Mitchell, John T, Miura, Michael A, Marchetti, Edmund K, Bartlett, Giorgos C, Karakousis
Publikováno v:
Journal of the American Academy of Dermatology. 88:802-807
Given the results of the recent KEYNOTE-716 trial, the performance of sentinel lymph node (SLN) biopsy for patients with clinical stage IIB/C melanoma has been questioned.Determine the utility of SLN status in guiding the recommendations for adjuvant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5aa47dd3f4bd0f31bf38348820ae8
https://doi.org/10.1016/j.jaad.2022.11.033
https://doi.org/10.1016/j.jaad.2022.11.033
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 149:2345-2354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7bc5e869b3444e247821cff16b7553e
https://doi.org/10.1007/s00432-023-04590-9
https://doi.org/10.1007/s00432-023-04590-9
Autor:
Bin Wu, Di-Ao Liu, Lei Guan, Phyoe Kyawe Myint, LiKang Chin, Hien Dang, Ye Xu, Jinqi Ren, Ting Li, Ziyan Yu, Sophie Jabban, Gordon B. Mills, Jonathan Nukpezah, Youhai H. Chen, Emma E. Furth, Phyllis A. Gimotty, Rebecca G. Wells, Valerie M. Weaver, Ravi Radhakrishnan, Xin Wei Wang, Wei Guo
Publikováno v:
Nature Cell Biology. 25:415-424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df697a91819629ba021fe92c7958eab
https://doi.org/10.1038/s41556-023-01092-1
https://doi.org/10.1038/s41556-023-01092-1
Autor:
George Coukos, Andrea Facciabene, Lana E Kandalaft, Christopher Neal, Dallas Flies, Justine Michaux, HuiSong Pak, Michal Bassani-Sternberg, Sarah F Adams, Sylvie Rusakiewicz, Georgia A McCann, Alizée J Grimm, Cheryl L-L Chiang, Ananda Mookerjee, Stephanie Jean, Florian Huber, Denarda Dangaj, Phyllis A Gimotty
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Novel therapeutic strategies in ovarian cancer (OC) are needed as the survival rate remains dismally low. Although dendritic cell-based cancer vaccines are effective in eliciting therapeutic responses, their complex and costly manufacturin
Externí odkaz:
https://doaj.org/article/d316f697081c43c3827481d33801e498