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of 3
pro vyhledávání: '"Phylinda L.S. Chan"'
Autor:
Phylinda L.S. Chan, Lynn McFadyen, Andrea Quaye, Heidi Leister‐Tebbe, Victoria M. Hendrick, Jennifer Hammond, Susan Raber
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 6, Pp 551-563 (2021)
Abstract A model‐informed drug development approach was used to select ceftaroline fosamil high‐dose regimens for pediatric patients with complicated skin and soft‐tissue infections caused by Staphylococcus aureus with a ceftaroline minimum inh
Externí odkaz:
https://doaj.org/article/16886efaec0e4d8097a53747c9861115
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 1, Pp 125-136 (2020)
Modeling and simulation provides quantitative information on target coverage for dose selection. Optimal model selection often relies on fit criteria and is not necessarily mechanistically driven. One such case is discussed where healthy volunteer da
Externí odkaz:
https://doaj.org/article/4f4b37dcf4334c428334cc71d9862696
Autor:
Sima S. Toussi, Joel Michael Neutel, Jesus Navarro, Richard Alfred Preston, Haihong Shi, Olga Kavetska, Robert R. LaBadie, Michael Binks, Phylinda L.S. Chan, Neil Demers, Brian Corrigan, Bharat Damle
Publikováno v:
Clinical pharmacology and therapeutics. 112(4)
Nirmatrelvir coadministered with ritonavir is highly efficacious in reducing the risk of coronavirus disease 2019 (COVID-19) adverse outcomes among patients at increased risk of progression to severe disease, including patients with chronic kidney di