Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Phuong-Uyen Dinh"'
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Exosomes are 30 to 100 nm extracellular vesicles that are secreted by many cell types. Initially viewed as cellular garbage with no biological functions, exosomes are now recognized for their therapeutic potential and used in regenerative medicine. C
Externí odkaz:
https://doaj.org/article/84b8746c56da4a82a9f02212c67b3599
Autor:
Junnan Tang, Deliang Shen, Thomas George Caranasos, Zegen Wang, Adam C. Vandergriff, Tyler A. Allen, Michael Taylor Hensley, Phuong-Uyen Dinh, Jhon Cores, Tao-Sheng Li, Jinying Zhang, Quancheng Kan, Ke Cheng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Stem cells exert their beneficial effects through secretion of regenerative factors. Here, the authors take the membranes and secreted factors from cardiac stem cells and generate a synthetic cell-mimicking microparticle, which, on injection in a mou
Externí odkaz:
https://doaj.org/article/68e90f01537b4132b5e027e02c99e7f0
Publikováno v:
Medicine in Drug Discovery, Vol 3, Iss , Pp - (2019)
For over a century, researchers have focused on how to optimize drug delivery. Systemic administration means that the drug becomes dilute and has the potential to diffuse to all tissues, which is only until the immune system steps in and rapidly clea
Externí odkaz:
https://doaj.org/article/f708cb9748b34922a0d95db036658841
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39361- (2024)
This study aimed to examine the key factors that influence entrepreneurial innovation and organizational performance, specifically focusing on the impact of environmental policy instruments, intellectual capital, and organizational learning. In the c
Externí odkaz:
https://doaj.org/article/e9ddc3cd5d1542bca1ebf8def88ebd77
Publikováno v:
Journal of Open Innovation: Technology, Market and Complexity, Vol 9, Iss 4, Pp 100150- (2023)
This study aims to identify key determinants impacting technology innovation and organizational performance, investigating how technological complexity and co-creation can enhance technology innovation and organizational performance. It also examines
Externí odkaz:
https://doaj.org/article/2a0cde2289e647b389f0db6ac7efbe3c
Autor:
Ke Cheng, Mark G. Lewis, Hanne Leth Andersen, Anthony L. Cook, Kristen D. Popowski, Zhenzhen Wang, Dashuai Zhu, Leonard J. Lobo, Laurent Pessaint, Phuong-Uyen Dinh, Halle Lutz, Jack Greenhouse, Shiqi Hu, Zhenhua Li
Publikováno v:
Nature nanotechnology
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has grown into a global pandemic, and only a few antiviral treatments have been approved to date. Angiotensin-converting enzyme 2 (ACE2) play
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 7, Pp 786-798 (2020)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Idiopathic pulmonary fibrosis is a lethal interstitial lung disease with unknown etiology, no cure, and few treatment options. Herein, a therapy option is presented that makes use of a heterogeneous population of lung cells, including progenitor cell
Autor:
Dipti Paudel, Phuong-Uyen Dinh, Kenneth B. Adler, Tyler A. Allen, Kristen D. Popowski, M. Cyndell Gracieux, Lauren V. Schnabel, Ke Huang, Leonard J. Lobo, Raina T. Barrio, Kevin Blackburn, Erin Harrell, Thomas G. Caranasos, Hayden N. Brochu, Shiqi Hu, Michael B. Goshe, Xinxia Peng, Arianna George, M. Taylor Hensley, Ke Cheng, Adam C. Vandergriff, Jhon Cores
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Idiopathic pulmonary fibrosis (IPF) is a fatal and incurable form of interstitial lung disease in which persistent injury results in scar tissue formation. As fibrosis thickens, the lung tissue loses the ability to facilitate gas exchange and provide
Publikováno v:
ACS Nano. 13:11273-11282
Human dermal fibroblasts (HDFs), the main cell population of the dermis, gradually lose their ability to produce collagen and renew intercellular matrix with aging. One clinical application for the autologous trans-dermis injection of HDFs that has b
Autor:
Teng Su, Ke Huang, Hui Zhang, Shiqi Hu, Zhenhua Li, Adam C. Vandergriff, Qi Yin, Yongjun Li, Suyun Liu, Li Qiao, Jhon Cores, Ke Cheng, Junnan Tang, Hong Ma, Tyler A. Allen, Phuong-Uyen Dinh
Publikováno v:
Journal of Clinical Investigation. 129:2237-2250
Exosomes, as functional paracrine units of therapeutic cells, can partially reproduce the reparative properties of their parental cells. The constitution of exosomes, as well as their biological activity, largely depends on the cells that secrete the