Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Phuong-Cac T Nguyen"'
Autor:
Jasper C Lin, Ruth A Ettinger, Jason T Schuman, Ai-Hong Zhang, Muhammad Wamiq-Adhami, Phuong-Cac T Nguyen, Shelley M Nakaya-Fletcher, Komal Puranik, Arthur R Thompson, Kathleen P Pratt
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116577 (2015)
The development of neutralizing anti-factor VIII (FVIII) antibodies complicates the treatment of many hemophilia A patients. The C-terminal C2 domain is a particularly antigenic FVIII region. A crystal structure of recombinant FVIII-C2 bound to an Fa
Externí odkaz:
https://doaj.org/article/9f01ce1acfea4daca262cfb00998c208
Autor:
Muhammad Wamiq-Adhami, Arthur R. Thompson, Jason T. Schuman, Jasper C. Lin, Phuong-Cac T. Nguyen, Kathleen P. Pratt, Ruth A. Ettinger, Ai-Hong Zhang, Shelley M. Nakaya-Fletcher, Komal Puranik
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 1, p e0116577 (2015)
PLoS ONE, Vol 10, Iss 1, p e0116577 (2015)
The development of neutralizing anti-factor VIII (FVIII) antibodies complicates the treatment of many hemophilia A patients. The C-terminal C2 domain is a particularly antigenic FVIII region. A crystal structure of recombinant FVIII-C2 bound to an Fa
Autor:
Pete Lollar, Ruth A. Ettinger, Shannon L. Meeks, Jasper C. Lin, John F. Healey, Jason T. Schuman, Phuong-Cac T. Nguyen, Kenneth B. Lewis, Kathleen P. Pratt
Publikováno v:
Blood. 123(17)
Neutralizing anti-factor VIII (FVIII) antibodies that develop in patients with hemophilia A and in murine hemophilia A models, clinically termed “inhibitors,” bind to several distinct surfaces on the FVIII-C2 domain. To map these epitopes at high
Publikováno v:
Analytical chemistry. 79(12)
The surface structure and DNA hybridization performance of thiolated single-strand DNA (HS-ssDNA) covalently attached to a maleimide-ethylene glycol disulfide (MEG) monolayer on gold have been investigated. Monolayer immobilization chemistry and surf
Autor:
Nigel S. Key, Dana C. Matthews, Jason T. Schuman, Phuong-Cac T. Nguyen, Tom E. Howard, Kenneth B. Lewis, Kathleen P. Pratt, Christopher E. Walsh, Neil C. Josephson
Publikováno v:
Blood. 118:202-202
Abstract 202 Development of neutralizing anti-factor VIII (FVIII) allo-antibodies (“inhibitors”) occurs in a significant proportion of congenital Hemophilia A (HA) patients receiving exogenous FVIII, and autoimmune responses to FVIII can also occ
Autor:
Kathleen P. Pratt, Kenneth B. Lewis, Pete Lollar, Shannon L. Meeks, Jason T. Schuman, Phuong-Cac T. Nguyen, John F. Healey
Publikováno v:
Blood. 118:203-203
Abstract 203 Neutralizing anti-factor VIII (FVIII) antibodies that develop in hemophilia A mice following exposure to human FVIII bind to several distinct regions (B-cell epitopes) on the FVIII C2 domain. This 19-kDa region of FVIII binds to thrombin
Autor:
Phuong-Cac T. Nguyen1, Lewis, Kenneth B.1, Ettinger, Ruth A.1, Schuman, Jason T.2, Lin, Jasper C.1, Healey, John F.3, Meeks, Shannon L.3, Lollar, Pete3, Pratt, Kathleen P.1,4,5 kathleen.pratt@usuhs.edu
Publikováno v:
Blood. 4/24/2014, Vol. 123 Issue 17, p2732-2739. 8p.