Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Phuong Trang Nguyen"'
Autor:
Nadjib Kihal, Phuong Trang Nguyen, Ali Nazemi, Andrea A. Greschner, Marc A. Gauthier, Steve Bourgault
Publikováno v:
Aggregate, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract The deposition of insoluble proteinaceous aggregates in the form of amyloid fibrils within the extracellular space of tissues is associated with numerous diseases. The development of molecular approaches to arrest amyloid formation and preve
Externí odkaz:
https://doaj.org/article/8a7b073bebaf465984d2797aa76b2b6e
Autor:
Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and postsynaptic assembly. How these extracellular interactions translate into intracellular
Externí odkaz:
https://doaj.org/article/b0e5ea6d61414d33a1c87b6f1bb93555
Autor:
Mathilde Fortier, Mélanie Côté-Cyr, Vy Nguyen, Margaryta Babych, Phuong Trang Nguyen, Roger Gaudreault, Steve Bourgault
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The islet amyloid polypeptide (IAPP) is a 37-residue aggregation-prone peptide hormone whose deposition as insoluble fibrils in the islets of Langerhans is associated with type II diabetes. Therapeutic interventions targeting IAPP amyloidogenesis, wh
Externí odkaz:
https://doaj.org/article/ffea88f71a8c4e1e8dd62149cfd92b4f
Autor:
Phuong Trang Nguyen, Ximena Zottig, Mathew Sebastiao, Alexandre A. Arnold, Isabelle Marcotte, Steve Bourgault
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Nguyen et al identified cytotoxic amyloid fibrils with oligomer-like characteristics, which were assembled from an islet amyloid polypeptide (IAPP) derivative containing an Asn-to-Gln substitution (N21Q). They presented evidence to show that these st
Externí odkaz:
https://doaj.org/article/28feaf14cc72438f8c537516bcfa2027
Autor:
Benjamin Feller, Aurélie Fallon, Wen Luo, Phuong Trang Nguyen, Irina Shlaifer, Alfred Kihoon Lee, Nicolas Chofflet, Nayoung Yi, Husam Khaled, Samer Karkout, Steve Bourgault, Thomas M. Durcan, Hideto Takahashi
Publikováno v:
Cells, Vol 12, Iss 7, p 1083 (2023)
Synucleinopathies form a group of neurodegenerative diseases defined by the misfolding and aggregation of α-synuclein (α-syn). Abnormal accumulation and spreading of α-syn aggregates lead to synapse dysfunction and neuronal cell death. Yet, little
Externí odkaz:
https://doaj.org/article/ec846f0a1d9c4c59a6b9e39268220685
Autor:
Brandon Andrade-Gagnon, Marilyne Bélanger-Bouliga, Phuong Trang Nguyen, Thi Hong Diep Nguyen, Steve Bourgault, Ali Nazemi
Publikováno v:
Nanomaterials, Vol 11, Iss 1, p 161 (2021)
Polymeric nanomaterials that degrade in acidic environments have gained considerable attention in nanomedicine for intracellular drug delivery and cancer therapy. Among various acid-degradable linkages, spirocyclic acetals have rarely been used to fa
Externí odkaz:
https://doaj.org/article/6c94026bee364f27946715c0bd574890
Publikováno v:
Journal of Diabetes Research, Vol 2015 (2015)
Type II diabetes mellitus is associated with the deposition of fibrillar aggregates in pancreatic islets. The major protein component of islet amyloids is the glucomodulatory hormone islet amyloid polypeptide (IAPP). Islet amyloid fibrils are virtual
Externí odkaz:
https://doaj.org/article/fc9b4d76b1aa41a695f5a962fc8c44bf
Autor:
Dinh Duy Vu, Syed Noor Muhammad Shah, Mai Phuong Pham, Van Thang Bui, Minh Tam Nguyen, Thi Phuong Trang Nguyen
Publikováno v:
BMC Plant Biology, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Understanding the genetic diversity in endangered species that occur inforest remnants is necessary to establish efficient strategies for the species conservation, restoration and management. Panax vietnamensis Ha et Grushv. is me
Externí odkaz:
https://doaj.org/article/505c249d777b4375ab542b9aeafb4e05
Publikováno v:
Langmuir. 39:5851-5860
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e866ec5a277e50ac69d2f8e8e7412e
https://doi.org/10.1021/acs.langmuir.3c00264
https://doi.org/10.1021/acs.langmuir.3c00264
Publikováno v:
Polish Journal of Food and Nutrition Sciences. :50-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb6c1e02448aa04e5e75139d4fa4c04
https://doi.org/10.31883/pjfns/159360
https://doi.org/10.31883/pjfns/159360