Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Phuong N. Dang"'
Autor:
Samuel Herberg, Daniel Varghai, Daniel S. Alt, Phuong N. Dang, Honghyun Park, Yuxuan Cheng, Jung-Youn Shin, Anna D. Dikina, Joel D. Boerckel, Marsha W. Rolle, Eben Alsberg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Herberg et al. previously showed functional healing of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates with localized morphogen presentation. In this study, they report the importance of the tubular geometry of MSC
Externí odkaz:
https://doaj.org/article/ca034ebc68764f5a85b780ac8aa721e4
Publikováno v:
Acta Biomaterialia. 95:408-417
Three-dimensional (3D) multicellular aggregates, in comparison to two-dimensional monolayer culture, can provide tissue culture models that better recapitulate the abundant cell-cell and cell-matrix interactions found in vivo. In addition, aggregates
Autor:
Honghyun Park, Yuxuan Cheng, Joel D. Boerckel, Samuel Herberg, Jung-Youn Shin, Eben Alsberg, Daniel Varghai, Phuong N. Dang, Anna D. Dikina, Daniel S. Alt, Marsha W. Rolle
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Biomimetic bone tissue engineering strategies partially recapitulate development. We recently showed functional restoration of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates featuring localized morphogen presentati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898e3b4ec73a213e9fd38e45fe0c0494
Autor:
Daniel Varghai, Eben Alsberg, Phuong N. Dang, Yuxuan Cheng, Samuel Herberg, Anna D. Dikina, Marsha W. Rolle
Publikováno v:
Nanotheranostics
Emerging biomimetic tissue engineering strategies aim to partially recapitulate fundamental events that transpire during embryonic skeletal development; namely, cellular self-organization and targeted morphogenetic pathway activation. Here, we descri
Autor:
Daniel S. Alt, Honghyun Park, Yuxuan Cheng, Joel D. Boerckel, P. C. Wong, Felicia He, Anna D. Dikina, Samuel Herberg, Yu Bin Lee, Phuong N. Dang, Alexandra McMillan, Rui Tang, James H. Dawahare, Eben Alsberg, Daniel Varghai, Kentaro Umemori, Anna M. McDermott, Jung Youn Shin
Publikováno v:
Science Advances
Mesenchymal condensations promote defect repair by mimicking cellular, morphogenetic, and mechanical aspects of bone development.
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell c
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell c
Autor:
Samuel Herberg, Honghyun Park, Felicia He, Phuong N. Dang, Anna D. Dikina, Daniel Varghai, Yuxuan Cheng, Joel D. Boerckel, Alexandra McMillan, Yu Bin Lee, Daniel S. Alt, Jung Youn Shin, P. C. Wong, Anna M. McDermott, Eben Alsberg, James H. Dawahare, Kentaro Umemori, Rui Tang
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation and is directed by local morphogen signals and mechanical cues. Here, we aimed to mimic these developmental conditions for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8351e76ec2eba1111980c4f1ed9262
https://doi.org/10.1101/561837
https://doi.org/10.1101/561837
Publikováno v:
Innovation in Aging
The purpose of this study was to examine the effects of a community and technology-based intervention to support self-managing hypertension in African American (AA). Sixty AA with hypertension were randomly assigned to Coachman (a technology-based in
Publikováno v:
Journal of the American College of Cardiology. 76:B64
Autor:
Cong Truc Huynh, Samuel Herberg, Alexandra McMillan, Phuong N. Dang, Minh Khanh Nguyen, Davood Varghai, Hooman Riazi, Eben Alsberg, Oju Jeon
Publikováno v:
Acta biomaterialia. 75
RNA interference (RNAi) may be an effective and valuable tool for promoting the growth of functional tissue, as short interfering RNA (siRNA) and microRNA (miRNA) can block the expression of genes that have negative effects on tissue regeneration. Ou
Autor:
William L. Murphy, Xiaohua Yu, Lauren M. Phillips, Eben Alsberg, Caitlin Bowerman, Neha Dwivedi, Phuong N. Dang
Publikováno v:
ACS Biomaterials Science & Engineering. 2:30-42
Since hydroxyapatite and bone morphogenetic protein-2 (BMP-2) can regulate chondrogenesis and osteogenesis, their individual and combined effects on endochondral ossification within human bone marrow-derived stem cell (hMSC) aggregates were investiga