Myosin forces elicit an F-actin structural landscape that mediates mechanosensitive protein recognition.

Autor: Carl AG; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA.; Tri-Institutional Program in Chemical Biology, The Rockefeller University, New York, NY, USA., Reynolds MJ; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA., Gurel PS; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA., Phua DYZ; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA., Sun X; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA., Mei L; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA.; Tri-Institutional Program in Chemical Biology, The Rockefeller University, New York, NY, USA., Hamilton K; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA., Takagi Y; Laboratory of Molecular Physiology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA., Noble AJ; Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA., Sellers JR; Laboratory of Molecular Physiology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA., Alushin GM; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 17. Date of Electronic Publication: 2024 Aug 17.

Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains.

Autor: Sun X; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY 10065, USA., Phua DYZ; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY 10065, USA., Axiotakis L Jr; Laboratory of Macromolecular Interactions, Cell Biology and Physiology Center, Division of Intramural Research, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Smith MA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA., Blankman E; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA., Gong R; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY 10065, USA., Cail RC; Laboratory of Macromolecular Interactions, Cell Biology and Physiology Center, Division of Intramural Research, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Espinosa de Los Reyes S; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY 10065, USA., Beckerle MC; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA., Waterman CM; Cell and Developmental Biology Center, Division of Intramural Research, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Alushin GM; Laboratory of Structural Biophysics and Mechanobiology, The Rockefeller University, New York, NY 10065, USA; Laboratory of Macromolecular Interactions, Cell Biology and Physiology Center, Division of Intramural Research, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA. Electronic address: galushin@rockefeller.edu.

Publikováno v: Developmental cell [Dev Cell] 2020 Nov 23; Vol. 55 (4), pp. 468-482.e7. Date of Electronic Publication: 2020 Oct 14.