Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Phu V. Tran"'
Autor:
Shirelle X. Liu, Aarthi Ramakrishnan, Li Shen, Jonathan C. Gewirtz, Michael K. Georgieff, Phu V. Tran
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Iron deficiency (ID) during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive hippocampal gene dysregulation. Prenatal choline supplementation partially normalizes these effect
Externí odkaz:
https://doaj.org/article/511ec710533a4bcf895fd68df659afb4
Autor:
David E. Condon, Phu V. Tran, Yu-Chin Lien, Jonathan Schug, Michael K. Georgieff, Rebecca A. Simmons, Kyoung-Jae Won
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Identification of differentially methylated regions (DMRs) is the initial step towards the study of DNA methylation-mediated gene regulation. Previous approaches to call DMRs suffer from false prediction, use extreme resources, an
Externí odkaz:
https://doaj.org/article/844f63a9e4c34a6f8da4fceb6e44810e
Autor:
Anish Deshpande, Remitha M. Vinayakamoorthy, Brijesh K. Garg, Jaya Prakash Thummapudi, Gauri Oza, Ketaki Adhikari, Aayush Agarwal, Parnika Dalvi, Swetha Iyer, Sarulatha Thulasi Raman, Vijay Ramesh, Akshitha Rameshbabu, Alexandra Rezvaya, Sneha Sukumaran, Sweta Swaminathan, Bhargav Tilak, Zhiyuan Wang, Phu V. Tran, Ralph H. Loring
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 470 (2020)
Alpha7 nicotinic acetylcholine receptors (α7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [αBGT] binding). While kn
Externí odkaz:
https://doaj.org/article/f567f2bd8446406ebedf129b5720431b
Publikováno v:
Dev Neurosci
Iron deficiency (ID) during neurodevelopment is associated with lasting cognitive and socioemotional deficits and increased risk for neuropsychiatric disease throughout the lifespan. These neurophenotypical changes are underlain by gene dysregulation
Autor:
Michael K. Georgieff, Garima Singh, Tate Gisslen, Phu V. Tran, Diana Wallin, Juan E. Abrahante Lloréns, Henry A. Feldman
Publikováno v:
Pediatric Research. 92:712-720
Background Phlebotomy-induced anemia (PIA) is universal and variable in degree among preterm infants and may contribute to neurodevelopmental risk. In mice, PIA causes brain tissue hypoxia, iron deficiency, and long-term sex-dependent neurobehavioral
Autor:
Shirelle X. Liu, Tenille K. Fredrickson, Natalia Calixto Mancipe, Michael K. Georgieff, Phu V. Tran
Publikováno v:
Nutrients; Volume 15; Issue 6; Pages: 1316
BackgroundFetal-neonatal iron deficiency (ID) causes long-term neurocognitive and affective dysfunctions. Clinical and preclinical studies have shown that early-life ID produces sex-specific effects. However, little is known about the molecular mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9318a2801d3df9607bcd3845a7161889
https://doi.org/10.1101/2022.06.29.498159
https://doi.org/10.1101/2022.06.29.498159
Autor:
Shirelle X. Liu, Aarthi Ramakrishnan, Li Shen, Jonathan C. Gewirtz, Michael K. Georgieff, Phu V. Tran
Iron deficiency during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive and widespread hippocampal gene dysregulation. Globally, fetal-neonatal iron deficiency produces both long-term activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc710bcb854c3c47ec53606e7d4a6230
https://doi.org/10.1101/2022.06.07.495122
https://doi.org/10.1101/2022.06.07.495122
Autor:
Li-Lian Yuan, Lucy Vulchanova, Phu V. Tran, Montana B. Beeson, Victoria M. Rogness, Donald A. Simone, Sergey G. Khasabov
Publikováno v:
Neuroscience
Pain is a major health problem, affecting over fifty million adults in the US alone, with significant economic cost in medical care and lost productivity. Despite evidence implicating nicotinic acetylcholine receptors (nAChRs) in pathological pain, t
Autor:
Shirelle X. Liu, Amanda K. Barks, Scott Lunos, Jonathan C. Gewirtz, Michael K. Georgieff, Phu V. Tran
Publikováno v:
Nutrients, Vol 13, Iss 4527, p 4527 (2021)
Nutrients; Volume 13; Issue 12; Pages: 4527
Nutrients; Volume 13; Issue 12; Pages: 4527
Early-life iron deficiency (ID) causes long-term neurocognitive impairments and gene dysregulation that can be partially mitigated by prenatal choline supplementation. The long-term gene dysregulation is hypothesized to underlie cognitive dysfunction
Publikováno v:
Nutrients, Vol 13, Iss 3857, p 3857 (2021)
Nutrients
Nutrients
Iron deficiency (ID) anemia is the foremost micronutrient deficiency worldwide, affecting around 40% of pregnant women and young children. ID during the prenatal and early postnatal periods has a pronounced effect on neurodevelopment, resulting in lo