Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Phosphorylation/drug effects/genetics"'
Autor:
Johannes Roth, Yvonne Börgeling, Carolin Nordhoff, Mirco Schmolke, Dorothee Viemann, Stephan Ludwig
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, Vol. 289, No 1 (2014) pp. 13-27
Journal of Biological Chemistry, Vol. 289, No 1 (2014) pp. 13-27
Background: Early cytokine dysregulation upon infection with highly pathogenic avian influenza viruses (HPAIV) is a major determinant of viral pathogenicity. Results: p38 MAPK controls HPAIV-induced gene expression by regulating interferon synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4959712dd5724faba43ebc04f21f8bab
http://europepmc.org/articles/PMC3879537
http://europepmc.org/articles/PMC3879537
Autor:
Kumiko, Nagashima, Stuart D, Shumway, Sriram, Sathyanarayanan, Albert H, Chen, Brian, Dolinski, Youyuan, Xu, Heike, Keilhack, Thi, Nguyen, Maciej, Wiznerowicz, Lixia, Li, Bart A, Lutterbach, An, Chi, Cloud, Paweletz, Timothy, Allison, Youwei, Yan, Sanjeev K, Munshi, Anke, Klippel, Manfred, Kraus, Ekaterina V, Bobkova, Sujal, Deshmukh, Zangwei, Xu, Uwe, Mueller, Alexander A, Szewczak, Bo-Sheng, Pan, Victoria, Richon, Roy, Pollock, Peter, Blume-Jensen, Alan, Northrup, Jannik N, Andersen
Phosphoinositide-dependent kinase 1 (PDK1) is a critical activator of multiple prosurvival and oncogenic protein kinases and has garnered considerable interest as an oncology drug target. Despite progress characterizing PDK1 as a therapeutic target,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa77558274950b04bf7d0ff36cc73f0
http://hdl.handle.net/10722/156005
http://hdl.handle.net/10722/156005
Publikováno v:
The Journal of biological chemistry, 285 (51
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Endothelial cells (ECs) express a Nox2 enzyme, which, by generating reactive oxygen species (ROS), contributes to EC redox signaling and angiotensin II (AngII)-induced endothelial dysfunction. ECs also express abundantly an adenosine A(2A) receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7f2468fb8e9c9f71e6f0fc5a55bcee
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/124818
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/124818