Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Phosphoric Monoester Hydrolases/genetics"'
Autor:
Lei Wang, Thomas Kruse, Blanca López-Méndez, Yuqing Zhang, Chunlin Song, Lei Zhu, Bing Li, Jing Fang, Zhimin Lu, Jakob Nilsson, Gang Zhang
Publikováno v:
Wang, L, Kruse, T, López-Méndez, B, Zhang, Y, Song, C, Zhu, L, Li, B, Fang, J, Lu, Z, Nilsson, J & Zhang, G 2023, ' Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis ', Journal of Molecular Cell Biology, vol. 14, no. 11 . https://doi.org/10.1093/jmcb/mjac062
The Bub1 and BubR1 kinetochore proteins support proper chromosome segregation and mitotic checkpoint activity. Bub1 and BubR1 are paralogs with Bub1 being a kinase, while BubR1 localizes the PP2A-B56 protein phosphatase to kinetochores in humans. Whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1d22139b6487f1b3ccfaff078544a
https://curis.ku.dk/ws/files/348203017/mjac062.pdf
https://curis.ku.dk/ws/files/348203017/mjac062.pdf
Autor:
Roos, E, Soer, E C, Klompmaker, S, Meijer, Laura, Besselink, M G, Giovannetti, E, Heger, M, Kazemier, G, Klümpen, H J, Takkenberg, R B, Wilmink, H, Würdinger, T, Dijk, F, van Gulik, T M, Verheij, J, van de Vijver, M J, Afd Pharmaceutics, Sub Membrane Biochemistry & Biophysics, Pharmaceutics
Publikováno v:
Critical Reviews in Oncology/Hematology, 140, 8. Elsevier Ireland Ltd.
Roos, E, Soer, E C, Klompmaker, S, Meijer, L L, Besselink, M G, Giovannetti, E, Heger, M, Kazemier, G, Klümpen, H J, Takkenberg, R B, Wilmink, H, Würdinger, T, Dijk, F, van Gulik, T M, Verheij, J & van de Vijver, M J 2019, ' Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract ', Critical Reviews in Oncology/Hematology, vol. 140, pp. 8-16 . https://doi.org/10.1016/j.critrevonc.2019.05.011
Roos, E, Soer, E C, Klompmaker, S, Meijer, L L, Besselink, M G, Giovannetti, E, Heger, M, Kazemier, G, Klümpen, H J, Takkenberg, R B, Wilmink, H, Würdinger, T, Dijk, F, van Gulik, T M, Verheij, J & van de Vijver, M J 2019, ' Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract ', Critical Reviews in Oncology/Hematology, vol. 140, pp. 8-16 . https://doi.org/10.1016/j.critrevonc.2019.05.011
Biliary tract carcinoma (BTC) comprises gallbladder and intra-/extrahepatic cholangiocarcinoma (GBC, ICC, EHC), which are currently classified by anatomical origin. Better understanding of the mutational profile of BTCs might refine classification an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64563fc2213fbeca1732853fe1f43b9
https://pubmed.ncbi.nlm.nih.gov/31158800
https://pubmed.ncbi.nlm.nih.gov/31158800
Autor:
Marina Santos, Rita Mota, Roberto De Philippis, Carlos Flores, Zsófia Büttel, Luís Gales, Paula Tamagnini, José P. Leite, João H. Morais-Cabral, Federico Rossi, Sara Pereira, Carina Eisfeld
Publikováno v:
MicrobiologyOpen
'MicrobiologyOpen ', vol: 8, pages: e753-1-e753-15 (2019)
MicrobiologyOpen, Vol 8, Iss 6, Pp n/a-n/a (2019)
MicrobiologyOpen, 8(6)
'MicrobiologyOpen ', vol: 8, pages: e753-1-e753-15 (2019)
MicrobiologyOpen, Vol 8, Iss 6, Pp n/a-n/a (2019)
MicrobiologyOpen, 8(6)
Many cyanobacteria produce extracellular polymeric substances (EPS) mainly composed of heteropolysaccharides with unique characteristics that make them suitable for biotechnological applications. However, manipulation/optimization of EPS biosynthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec5d07d113996cc5b37ba77ab7f1d62
https://hdl.handle.net/11568/1149734
https://hdl.handle.net/11568/1149734
Autor:
Olivier Jousson, Christophe Mas, Pierre Hutter, Colette Rossier, Stylianos E. Antonarakis, Nathalie Scamuffa, Robert Lyle, Michel Guipponi, Paolo Meda, Alexandre Reymond, Caroline Tapparel
Publikováno v:
Human Genetics, Vol. 109, No 6 (2001) pp. 569-575
The human TPTE gene encodes a testis-specific protein that contains four potential transmembrane domains and a protein tyrosine phosphatase motif, and shows homology to the tumor suppressor PTEN/MMAC1. Chromosomal mapping revealed multiple copies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f5d2e0316454b1473dc21897b7c007
http://doc.rero.ch/record/321876/files/439_2014_Article_607.pdf
http://doc.rero.ch/record/321876/files/439_2014_Article_607.pdf
Autor:
Aline X.S. Santos, Fabrice P. A. David, Manuele Piccolis, Isabelle Riezman, Maria Auxiliadora Aguilera-Romero, Olivier Schaad, Robbie Loewith, Howard Riezman
Publikováno v:
Molecular biology of the cell
Molecular Biology of the Cell, Vol. 25, No 20 (2014) pp. 3234-3246
Molecular Biology of the Cell
Molecular Biology of the Cell, Vol. 25, No 20 (2014) pp. 3234-3246
Molecular Biology of the Cell
An unbiased mass spectrometry–based lipidomic screening method is used to analyze the major lipids of yeast deletions in protein kinase/phosphatase genes. This creates a new, rich source of biological insight. It uncovers new players in lipid homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c30f14174777f0f9a736fb5f8a9cca
Autor:
Margarida Moura, Carlos Conde
Publikováno v:
Biomolecules, Vol 9, Iss 2, p 55 (2019)
Biomolecules
Biomolecules
Mitosis requires extensive rearrangement of cellular architecture and of subcellular structures so that replicated chromosomes can bind correctly to spindle microtubules and segregate towards opposite poles. This process originates two new daughter n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be77cdce2455c82c38b4c2814cf7a33b
https://doi.org/10.3390/biom9020055
https://doi.org/10.3390/biom9020055
Autor:
André Bodson, Jens Behrends, G. Servais, Dominique Gauguier, Evelyne Marion, Pamela J. Kaisaki, Daubresse Jc, Claude Szpirer, J. Mockel, Cyril Gueydan, Jonathan C. Levy, Georges Krzentowski, Valérie Pouillon, Stéphane Schurmans, Véronique Kruys
Publikováno v:
Scopus-Elsevier
Diabetes, 51
Diabetes, 51
Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and is thus a good candidate gene. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3155af37c1761a84281f3d6f79ec25e8
https://ora.ox.ac.uk/objects/uuid:92c3a867-8afa-473e-9daf-ff356eff3896
https://ora.ox.ac.uk/objects/uuid:92c3a867-8afa-473e-9daf-ff356eff3896
Publikováno v:
Microbiological Research. 166(5):380-90
Choline favors the pathogenesis of Pseudomonas aeruginosa because hemolytic phospholipase C and phosphorylcholine phosphatase (PchP) are synthesized as a consequence of its catabolism. The experiments performed here resulted in the identification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::d920b7bad25da0de8c0dbd830fd406de
https://doi.org/10.1016/j.micres.2010.07.004
https://doi.org/10.1016/j.micres.2010.07.004
Autor:
Gilbert Di Paolo, Laurent Cimasoni, Samuel G. Frere, Markus R. Wenk, Silvia Giovedì, Elizabeth A. Pollina, Hong Zhang, Ottavio Arancio, Katheleen Gardiner, Sergey V. Voronov, Pietro De Camilli, Cecilia Schmidt, Stylianos E. Antonarakis, Christelle Borel, Muriel T. Davisson, Ellen C. Akeson
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 105, No 27 (2008) pp. 9415-9420
Phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P 2 ] is a signaling phospholipid implicated in a wide variety of cellular functions. At synapses, where normal PtdIns(4,5)P 2 balance is required for proper neurotransmission, the phosphoinositide ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3723e9d4ff769f7c7e02356a27ea9bfe
https://doi.org/10.1073/pnas.0803756105
https://doi.org/10.1073/pnas.0803756105
Autor:
Tania Attié-Bitach, Sophie Saunier, Mandy Kwong, Nadia Elkhartoufi, Enza Maria Valente, Isabelle Perrault, Joseph G. Gleeson, Alessia Micalizzi, Stéphanie Le Corre, Marta Romani, Julie Litzler, Lydie Burglen, Iain A. Drummond, Kevin J. Wright, Avinash Abhyankar, Julien Saada, Jean-Laurent Casanova, Stanislas Lyonnet, Nathalie Boddaert, Nicolas Chassaing, Arnold Munnich, Jeanne Amiel, Peter K. Jackson, Emilie Filhol, Michel Vekemans, Ferechté Encha-Ravazi, Wolfgang Baehr, Sophie Thomas
Publikováno v:
Human Mutation
Human Mutation, Wiley, 2014, 35 (1), pp.137-146. ⟨10.1002/humu.22470⟩
Human Mutation, Wiley, 2014, 35 (1), pp.137-146. ⟨10.1002/humu.22470⟩
International audience; Joubert syndrome (JS) is characterized by a distinctive cerebellar structural defect, namely the << molar tooth sign >>. JS is genetically heterogeneous, involving 20 genes identified to date, which are all required for cilia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea54b2a50db5d77c8971d0cf7982565
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03240698
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03240698