Výsledky vyhledávání - "Phosphopyruvate Hydratase/metabolism"

Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus

Autor: Valentin Schmutz, Nicolas Toni, Mari A. Virtanen, Lucas A. Mongiat, Jan Armida, Matteo Bergami, Laszlo Vutskits, Marine Krzisch, Fred H. Gage, Alejandro F. Schinder, Jacqueline Kocher-Braissant, Silvio Gabriel Temprana, Karl-Klaus Conzelmann, Rudolf Kraftsik

Publikováno v: Brain Structure & Function
Brain structure & function
Brain Structure and Function, vol. 220, no. 4, pp. 2027-2042
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Brain Structure and Function, Vol. 220, No 4 (2015) pp. 2027-2042

The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4ce4747eb262a82ec34c49ed41eaac
http://doc.rero.ch/record/331327/files/429_2014_Article_768.pdf

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Circulating Levels of Brain-Enriched MicroRNAs Correlate with Neuron Specific Enolase after Cardiac Arrest—A Substudy of the Target Temperature Management Trial

Autor: Christian Hassager, Pascal Stammet, Niklas Nielsen, Lu Zhang, Michael A. Kuiper, Yvan Devaux, Patrik Gilje, Hans Friberg, Josef Dankiewicz, David Erlinge, Matt P. Wise, Francesca Maria Stefanizzi, Antonio Salgado-Somoza

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 12
Stefanizzi, F M, Nielsen, N, Zhang, L, Dankiewicz, J, Stammet, P, Gilje, P, Erlinge, D, Hassager, C, Wise, M P, Kuiper, M, Friberg, H, Devaux, Y & Salgado-Somoza, A 2020, ' Circulating Levels of Brain-Enriched MicroRNAs Correlate with Neuron Specific Enolase after Cardiac Arrest : A Substudy of the Target Temperature Management Trial ', International Journal of Molecular Sciences, vol. 21, no. 12, 4353 . https://doi.org/10.3390/ijms21124353
International Journal of Molecular Sciences, Vol 21, Iss 4353, p 4353 (2020)

Outcome prognostication after cardiac arrest (CA) is challenging. Current multimodal prediction approaches would benefit from new biomarkers. MicroRNAs constitute a novel class of disease markers and circulating levels of brain-enriched ones have bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ce183c43d487f79b51e3e5ac9c09d3

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Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

Autor: Jan Lopatar, Frank W. Pfrieger, Frédéric Cassé, Elias Gebara, Nicolas Toni, Paola Bezzi, Liyi Li, Sébastien Sultan, Jonathan Moss, Josef Bischofberger, Francesco Petrelli

Publikováno v: Neuron, vol. 88, no. 5, pp. 957-972
Neuron
Neuron, 2015, 88 (5), pp.957-972. ⟨10.1016/j.neuron.2015.10.037⟩

SummaryAdult neurogenesis is regulated by the neurogenic niche, through mechanisms that remain poorly defined. Here, we investigated whether niche-constituting astrocytes influence the maturation of adult-born hippocampal neurons using two independen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1759241220df0d9aae026bcfae793e9f
https://doi.org/10.1016/j.neuron.2015.10.037

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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain-A Journal of Neurology, 2018, 141 (5), pp.1434-1454. ⟨10.1093/brain/awy057⟩
Brain
Brain, vol. 141, no. 5, pp. 1434-1454

Expression of the neuronal kinase DCLK3 is reduced in Huntington’s disease. Galvan et al. report that DCLK3 silencing in the mouse striatum exacerbates the toxicity of mutant huntingtin, whereas DCLK3 overexpression is neuroprotective, and show tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eb0c82958019d7f33356d092f6de6863
https://hal.archives-ouvertes.fr/hal-02459743

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Cell-specific modulation of monocarboxylate transporter expression contributes to the metabolic reprograming taking place following cerebral ischemia

Autor: Ximena Castillo, Lorenz Hirt, Katia Rosafio, Luc Pellerin

Publikováno v: Neuroscience, vol. 317, pp. 108-120

Monocarboxylate transporters (MCTs) are involved in lactate trafficking and utilization by brain cells. As lactate is not only overproduced during ischemia but its utilization was shown to be essential upon recovery, we analyzed the expression of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb31e718cd85e64f7c1ce3a363ab02ed
https://pubmed.ncbi.nlm.nih.gov/26751713

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Reduction of seizure frequency after epilepsy surgery in a patient with STXBP1 encephalopathy and clinical description of six novel mutation carriers

Publikováno v: Epilepsia, Vol. 54, No 5 (2013) pp. e74-80
S, W, P, H, R, H, A, J, Møller, R S & Hjalgrim, H 2013, ' Reduction of seizure frequency after epilepsy surgery in a patient with STXBP1 encephalopathy and clinical description of six novel mutation carriers ', Epilepsia, vol. 54, no. 5, pp. e74-e80 . https://doi.org/10.1111/epi.12124
Epilepsia

Mutations in STXBP1 have been identified in a subset of patients with early onset epileptic encephalopathy (EE), but the full phenotypic spectrum remains to be delineated. Therefore, we screened a cohort of 160 patients with an unexplained EE, includ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c085243c07b5e3107dad68e7c3244521
https://archive-ouverte.unige.ch/unige:34839

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Proteomic analysis of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of retinoblastoma-interacting-zinc-finger protein

Autor: Livia Malorni, Annarita Farina, Bruno Moncharmont, Ciro Abbondanza, Gabriella Pocsfalvi, Antimo Di Maro, Augusto Parente, M. Rossi, and Antonio Malorni, Angela Chambery, Giuseppina Cacace

Publikováno v: Journal of proteome research
5 (2006): 1176–1185.
info:cnr-pdr/source/autori:Chambery Angela; Farina Annarita; Di Maro Antimo; Rossi Mariangela; Abbondanza Ciro; Moncharmont Bruno; Malorni Livia; Cacace Giuseppina; Pocsfalvi Gabriella; Malorni Antonio; Parente Augusto/titolo:Proteomic analysis of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of retinoblastoma-interacting-zinc-finger protein./doi:/rivista:Journal of proteome research (Print)/anno:2006/pagina_da:1176/pagina_a:1185/intervallo_pagine:1176–1185/volume:5
Journal of Proteome Research, Vol. 5, No 5 (2006) pp. 1176-85

To identify a growth-promoting activity related to retinoblastoma-interacting-zinc-finger (RIZ) protein, differential protein expression of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of RIZ protein was analyzed by a robust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3c914a4d69bf141703cc37020460c1
https://pubmed.ncbi.nlm.nih.gov/16674107

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The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity

Autor: Joaquín Castilla, Elisabeth Vial-Knecht, Milene Russelakis-Carneiro, Kinsey Maundrell, Claudio Soto, Sonia Carboni, Sébastien Wälchli, Claudio Hetz

Publikováno v: Journal of Neuroscience, Vol. 25, No 11 (2005) pp. 2793-2802

Prion diseases are transmissible neurodegenerative disorders characterized by extensive neuronal apoptosis and accumulation of misfolded prion protein (PrPSC). Recent reports indicate that PrPSCinduces neuronal apoptosis via activation of the endopla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456872c31c01a16c48a8d858a92a31a1
https://archive-ouverte.unige.ch/unige:89902

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Bacterial variations on the methionine salvage pathway

Autor: Haas Dieter, Michoud Karine, Ashida Hiroki, Dénervaud Valérie, Sekowska Agnieszka, Yokota Akiho, Danchin Antoine

Publikováno v: BMC Microbiology
BMC Microbiology, vol. 4, pp. 9
BMC Microbiology, Vol 4, Iss 1, p 9 (2004)

BACKGROUND: The thiomethyl group of S-adenosylmethionine is often recycled as methionine from methylthioadenosine. The corresponding pathway has been unravelled in Bacillus subtilis. However methylthioadenosine is subjected to alternative degradative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bed2ce9184f3c1eefae84184038557c7
http://europepmc.org/articles/PMC395828

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GAD67-Mediated GABA Synthesis and Signaling Regulate Inhibitory Synaptic Innervation in the Visual Cortex

Autor: Bidisha Chattopadhyaya, Caizhi Wu, Z. Josh Huang, Graham Knott, Yu Fu, Graziella Di Cristo, Sandra J. Kuhlman, Richard D. Palmiter

Publikováno v: Neuron, vol. 54, no. 6, pp. 889-903

SummaryThe development of GABAergic inhibitory circuits is shaped by neural activity, but the underlying mechanisms are unclear. Here, we demonstrate a novel function of GABA in regulating GABAergic innervation in the adolescent brain, when GABA is m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3280d6d1f7daa10fc742def2bd8361

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