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pro vyhledávání: '"Phosphoproteins/ deficiency"'
Autor:
Agharul I. Choudhury, Steven J. Lingard, Shanta J. Persaud, Helen Heffron, Pedro Luis Herrera, Henry Asare-Anane, James Cantley, Dominic J. Withers, Colin Selman
Publikováno v:
Diabetologia, Vol. 50, No 6 (2007) pp. 1248-1256
AIMS/HYPOTHESIS: Insulin signalling pathways regulate pancreatic beta cell function. Conditional gene targeting using the Cre/loxP system has demonstrated that mice lacking insulin receptor substrate 2 (IRS2) in the beta cell have reduced beta cell m