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of 1 518
pro vyhledávání: '"Phospholipidosis"'
Akademický článek
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Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 24, Iss 3 (2024)
Amiodarone, potent antidysrhythmic, widely used drug that has been associated with hepatic toxicity in long-term or excessive use. In the presented study twelve rats were allocated into two groups and given daily doses via gastric gavage orally for t
Externí odkaz:
https://doaj.org/article/95efb910e7754ec390c09819f5a0ea38
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 7, Pp 100574- (2024)
Bis(monoacylglycerol)phosphate (BMP) is an acidic glycerophospholipid localized to late endosomes and lysosomes. However, the metabolism of BMP is poorly understood. Because many drugs that cause phospholipidosis inhibit lysosomal phospholipase A2 (L
Externí odkaz:
https://doaj.org/article/b880b882cd4b4b528a23c55087e6178c
Autor:
Takahiro Tsukimura, Koki Saito, Tomoko Shiga, Yasuhiro Ogawa, Hitoshi Sakuraba, Tadayasu Togawa
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 39, Iss , Pp 101079- (2024)
As a standard therapy for Fabry disease, enzyme replacement therapy (ERT) with recombinant human α-galactosidase A (α-Gal) has been successfully used, and the instructions for this drug state that “it should not be co-administrated with cationic
Externí odkaz:
https://doaj.org/article/d460088d15fa46e8915fb11dcfe579ec
Autor:
Amélie Friederike Menke, Barbara Heitplatz, Veerle Van Marck, Hermann Pavenstädt, Ulrich Jehn
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 14, Iss 1, Pp 20-29 (2024)
Introduction: Renal phospholipidosis describes the accumulation of phospholipids in the lysosomes of kidney cells, in particular podocytes. Originally, this was described primarily in the context of the lysosomal storage disorder Fabry disease. It is
Externí odkaz:
https://doaj.org/article/23f50167733540d6a08214782adabe6c
Akademický článek
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Publikováno v:
Farmacja Polska, Vol 78, Iss 11, Pp 628-634 (2023)
Adverse reactions of drugs are a significant problem in pharmacotherapy. The observed side effects may have multiple causes. They may depend on the dose and type of medicine used. They can occur during therapy or appear with a delay, after its comple
Externí odkaz:
https://doaj.org/article/12441ed3e65a4077919f37e717148d16
Publikováno v:
Medical Sciences, Vol 12, Iss 2, p 25 (2024)
Phospholipidosis is a rare disorder which consists of an excessive intracellular accumulation of phospholipids and the appearance of zebra bodies or lamellar bodies when looking at them using electron microscopy. This disease is associated with certa
Externí odkaz:
https://doaj.org/article/4fafe11e9f61441fb16a986a180dcf14
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Viktoria Diesendorf, Valeria Roll, Nina Geiger, Sofie Fähr, Helena Obernolte, Katherina Sewald, Jochen Bodem
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Recently, Tummino et al. reported that 34 compounds, including Chloroquine and Fluoxetine, inhibit SARS-CoV-2 replication by inducing phospholipidosis, although Chloroquine failed to suppress viral replication in Calu-3 cells and patients. In contras
Externí odkaz:
https://doaj.org/article/0cc3735267cd4a38b96cfdbf7bb379a8