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pro vyhledávání: '"Phospholipid efflux"'
Akademický článek
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Akademický článek
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Autor:
Yoshito Ikeda
Publikováno v:
YAKUGAKU ZASSHI. 140:1329-1334
Biliary lipids primarily consist of bile salts, phospholipids, and cholesterol. Bile salts have potent detergent properties and deleterious effects on the cell membrane and are cytotoxic to hepatocytes. We have previously reported that phosphatidylch
Autor:
Yoshito Ikeda
Publikováno v:
MEMBRANE. 45:182-186
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 285-292 (2009)
ABCA1 exports cholesterol and phospholipids from cells by a multistep pathway that involves forming cell surface lipid domains, solubilizing these lipids by apolipoproteins, binding of apolipoproteins to ABCA1, and activating signaling processes. Her
Externí odkaz:
https://doaj.org/article/0ff7875140ba447f93499be513c484c8
Autor:
Patrick Linsel-Nitschke, Andreas W. Jehle, Jing Shan, Guoqing Cao, Desa Bacic, Debin Lan, Nan Wang, Alan R. Tall
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 1, Pp 86-92 (2005)
ABCA7 is homologous to ABCA1 and has recently been shown in cell culture to bind apolipoprotein A-I (apoA-I) and to promote the efflux of phospholipids. However, it is not known if ABCA7 promotes lipid efflux in vivo. When expressed in HEK293 cells,
Externí odkaz:
https://doaj.org/article/07296337f0e345a282bd514e4fe0804b
Autor:
John F. Oram, Richard M. Lawn
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 8, Pp 1173-1179 (2001)
It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing excess cholesterol from arterial cells. A cellular A
Externí odkaz:
https://doaj.org/article/043540628582412fa786ed1b1c16156a
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 10, Pp 1769-1781 (1999)
High density lipoprotein (HDL) phospholipids and apolipoproteins remove cellular lipids by two distinct mechanisms, but their relative contribution to reverse cholesterol transport is unknown. Whereas phospholipid-mediated cholesterol efflux from cul
Externí odkaz:
https://doaj.org/article/6c86e6b0ee154698be35a6e0047d47bb
Autor:
Mary Jo LaDu, Brian T. Layden, Sue H. Lee, Kiira Ratia, Cutler T. Lewandowski, Manel Ben Aissa, Gregory R. J. Thatcher
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Selective liver X receptor (LXR) agonists have been extensively pursued as therapeutics for Alzheimer’s disease and related dementia (ADRD) and, for comorbidities such as type 2 diabetes (T2D) and cerebrovascular disease (CVD), di
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811560811
Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease, 1276, 67-83
Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease, 1276, 67-83
Most types of cells in the body have no or very limited capacity of catabolizing cholesterol, so cholesterol efflux is essential for cholesterol homeostasis. There are multiple mechanisms responsible for cellular cholesterol efflux. Among them, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3578756d7530252f538e04e0b16a2fa1
https://doi.org/10.1007/978-981-15-6082-8_6
https://doi.org/10.1007/978-981-15-6082-8_6