CcpA-dependent carbon catabolite repression in bacteria

Publikováno v: Microbiology and Molecular Biology Reviews. 67(4):475-490

Carbon catabolite repression (CCR) by transcriptional regulators follows different mechanisms in gram-positive and gram-negative bacteria. In gram-positive bacteria, CcpA-dependent CCR is mediated by phosphorylation of the phosphoenolpyruvate:sugar p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___01423::f3b35d26619b1a1cf410b83635a41d6d
https://research.rug.nl/en/publications/76b5a59c-4957-42cc-9a68-b630456dc892

An extended sampling of the configurational space of HPr fromE. coli

Autor: Herman J. C. Berendsen, N. A. J. Van Nuland, Ruud M. Scheek, B. L. de Groot, Andrea Amadei

Publikováno v: Proteins: Structure, Function, and Genetics. 26:314-322

Recently, we developed a method (Amadei et al., J. Biomol. Str. Dyn. 13: 615-626; de Groot et al., J. Biomol. Str. Dyn. 13: 741-751, 1996) to obtain an extended sampling of the configurational space of proteins, using an adapted form of molecular dyn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffe2c645245a61da0dfaeb20f218e2f0
https://doi.org/10.1002/(sici)1097-0134(199611)26:3<314::aid-prot7>3.0.co

Phosphorylation-induced torsion-angle strain in the active center of HPr, detected by NMR and restrained molecular dynamics refinement

Publikováno v: Protein Science. 5(3):442-446

The structure of the phosphorylated form of the histidine-containing phosphocarrier protein HPr from Escherichia coli has been solved by NMR and compared with that of unphosphorylated HPr. The structural changes that occur upon phosphorylation of His

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::49ad0eecc3c6f65349b462cb665b4326
https://hdl.handle.net/11370/0f5cfad0-b05f-46e1-8aa1-51d9975fd049

High-resolution structure of the histidine-containing phosphocarrier protein (HPr) from Staphylococcus aureus and characterization of its interaction with the bifunctional HPr kinase/phosphorylase

Autor: Hans Robert Kalbitzer, Wolfgang Hengstenberg, Norman Kachel, Sonja Hasenbein, Till Maurer, Claudia Elisabeth Munte, Sebastian Meier, Brigitte Koch

Publikováno v: Journal of bacteriology 186, 5906-5918 (2004). doi:10.1128/JB.186.17.5906-5918.2004

A high-resolution structure of the histidine-containing phosphocarrier protein (HPr) from Staphylococcus aureus was obtained by heteronuclear multidimensional nuclear magnetic resonance (NMR) spectroscopy on the basis of 1,766 structural restraints.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d298197bd59a0871ac4620f7977bf723
https://pubmed.ncbi.nlm.nih.gov/15317796

Transporters and their roles in LAB cell physiology

Autor: Poolman, Bert

Publikováno v: Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology, 82(1-4), 147-164. SPRINGER
Clinical and Experimental Pharmacology and Physiology, 29(11). Wiley-Blackwell

For most metabolic pathways, the uptake of the substrate into the cell represents the first step. This transport reaction can exert a large control on the flux through the pathway, in particular when the substrate concentration becomes limiting. Besi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b6b8f71a81f4ca6557fb5ccd2eeaf92a
https://research.rug.nl/en/publications/70cf788e-e5e3-4d8a-928b-38b50c86dc71