Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Phosphatidylinositol-4"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTThe gram-positive bacterium Staphylococcus aureus can invade non-professional phagocytic cells by associating with the plasma protein fibronectin to exploit host cell integrins. Integrin-mediated internalization of these pathogens is facilita
Externí odkaz:
https://doaj.org/article/a6af5c51003e4bf8bc7381b0af39308f
Regulation of enolase activation to promote neural protection and regeneration in spinal cord injury
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1457-1462 (2023)
Spinal cord injury (SCI) is a debilitating condition characterized by damage to the spinal cord resulting in loss of function, mobility, and sensation with no U.S. Food and Drug Administration-approved cure. Enolase, a multifunctional glycolytic enzy
Externí odkaz:
https://doaj.org/article/c3aabf5723a84655a7553989df5fba22
Publikováno v:
Glioma, Vol 3, Iss 3, Pp 135-142 (2020)
Background and Aim: Glioblastoma (GBM) is the most common and aggressive form of primary malignant brain tumors. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta (PIK3CD), which is overexpressed in GBM, is involved in GBM pathog
Externí odkaz:
https://doaj.org/article/40c6f5fcdd3c48288feb86b16719dc72
Akademický článek
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Autor:
Sami Gabbouj, Simo Ryhänen, Mikael Marttinen, Rebekka Wittrahm, Mari Takalo, Susanna Kemppainen, Henna Martiskainen, Heikki Tanila, Annakaisa Haapasalo, Mikko Hiltunen, Teemu Natunen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) and type 2 diabetes (T2D) are both diseases with increasing prevalence in aging populations. T2D, characterized by insulin resistance and defective insulin signaling, is a common co-morbidity and a risk factor for AD, incre
Externí odkaz:
https://doaj.org/article/15215aa0ee3d4acfb1f0bd56cde7b958
Phosphoinositides (PIs) are small, phosphorylated lipids that serve many functions in the cell. They regulate endo- and exocytosis, vesicular trafficking, actin reorganization, and cell mobility, and they act as signaling molecules. The most abundant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a28ae72fbf8a1d8262d9c330cd1170c
https://www.bib.irb.hr/1272864
https://www.bib.irb.hr/1272864
Autor:
Ismail Ben Soussia, Frank S. Choveau, Sandy Blin, Eun-Jin Kim, Sylvain Feliciangeli, Franck C. Chatelain, Dawon Kang, Delphine Bichet, Florian Lesage
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli, including bioactive lipids, mechanical stretch and temperature, into electrical signals. The nature of the structural changes that regulate their activity remains an ope
Externí odkaz:
https://doaj.org/article/67683d0d8ef84390be2c9f1f6e496be8
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
In today's world of modern medicine and novel therapies, cancer still remains to be one of the prime contributor to the death of people worldwide. The modern therapies improve condition of cancer patients and are effective in early stages of cancer b
Externí odkaz:
https://doaj.org/article/0e50cd554c0e401dad18b183137093e4
Autor:
Benjamin Marx, Daliborka Miller-Lazic, John Doorbar, Slawomir Majewski, Kay Hofmann, Martin Hufbauer, Baki Akgül
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The E6 oncoproteins of high-risk human papillomaviruses (HPV) of genus alpha contain a short peptide sequence at the carboxy-terminus, the PDZ binding domain, with which they interact with the corresponding PDZ domain of cellular proteins. Interestin
Externí odkaz:
https://doaj.org/article/65d1139a2d1e4fda9ed459e018ff7213
Autor:
Ana Bura, Antonija Jurak Begonja
Publikováno v:
Life, Vol 11, Iss 1331, p 1331 (2021)
Life; Volume 11; Issue 12; Pages: 1331
Life; Volume 11; Issue 12; Pages: 1331
Phosphoinositides (PIs) are phosphorylated membrane lipids that have a plethora of roles in the cell, including vesicle trafficking, signaling, and actin reorganization. The most abundant PIs in the cell are phosphatidylinositol-4,5-bisphosphate [PI(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c57a445b79e29950016196c769d84c
https://www.mdpi.com/2075-1729/11/12/1331
https://www.mdpi.com/2075-1729/11/12/1331