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pro vyhledávání: '"Phosphate-buffered solution"'
Akademický článek
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A Chitosan-PLGA based catechin hydrate nanoparticles used in targeting of lungs and cancer treatment
Autor:
Hassan Mohammed Ali Almatar, Aftab Alam, Ridha Abdullah Alrasheed, Rizwan Ahmad, Niyaz Ahmad, Taysser Mohammed Buheazah, Hassan Ali Al-Nasif, Hussain Salman AlHomoud, Abdullah Sami Al-Ramadan
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 9, Pp 2344-2357 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Objective: To prepare a novel Chitosan (CS)-coated-PLGA-NPs of catechin hydrate (CTH) and to improve lungs bioavailability via direct nose to lungs-delivery for the comparative assessment of a pulmokinetics study by the first-time UHPLC-MS/MS develop
'Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease'
Autor:
Alfredo Rodríguez-Cruz, Guadalupe García-Alcocer, Antonio Romo-Mancillas, Jesus Mendiola-Precoma, Laura C. Berumen, Jesica Escobar-Cabrera
Publikováno v:
IBRO Reports, Vol 8, Iss, Pp 28-35 (2020)
IBRO Reports
IBRO Reports
Highlights • Valerenic acid modulates the neuropathological markers of Parkinson´s disease. • Valerenic acid attenuates neuroinflammation in a Parkinson´s disease model. • Astrocytes and cytokines are targets in the anti-inflammatory effect o
Akademický článek
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Conference
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Autor:
Qinghua Dong, Jing Zhang, Guanyu Wang, Ximei Ma, Sherven Sharma, Difan Zhou, Zhenyu Liuyang, Zhuha Zhou, Mengjing Fan, Feichao Xuan, Yihong Wang, Zhiyao Xu, Yiyang Hong
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1274-1285 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1274-1285 (2021)
Liver is the most common metastatic site for colorectal cancer (CRC), there is no satisfied approach to treat CRC liver metastasis (CRCLM). Here, we investigated the role of a polycomb protein BMI-1 in CRCLM. Immunohistochemical analysis showed that
Autor:
Yixian Zhou, Jintao Fu, Biyuan Wu, Xin Pan, Yiting Zhao, Chuanbin Wu, Boyi Niu, Sulan Luo, Guilan Quan
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2404-2416 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2404-2416 (2020)
Pulmonary drug delivery has attracted increasing attention in biomedicine, and porous particles can effectively enhance the aerosolization performance and bioavailability of drugs. However, the existing methods for preparing porous particles using po
Autor:
So Hee Ko, Hyun Jik Lee, Sang Hun Lee, Gee Euhn Choi, Young Hyun Jung, Ho Jae Han, Sei Jung Lee
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 426-443 (2017)
Redox Biology
Redox Biology
Mitophagy under hypoxia is an important factor for maintaining and regulating stem cell functions. We previously demonstrated that fatty acid synthase (FASN) induced by hypoxia is a critical lipid metabolic factor determining the therapeutic efficacy
Publikováno v:
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
Journal of the Mechanical Behavior of Biomedical Materials
Journal of the Mechanical Behavior of Biomedical Materials
Tissue material properties are crucial to understanding their mechanical function, both in healthy and diseased states. However, in certain circumstances logistical limitations can prevent testing on fresh samples necessitating one or more freeze-tha
Publikováno v:
Virus Research
Highlights • RNA-Seq libraries were constructed using three methods. • RNA virome in ducks was detected. • RNA virome in mink was detected. • Various viruses in ducks or minks were possibly first identified.
Virome (viral megagenomics) d
Virome (viral megagenomics) d