Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Phong M. Truong"'
Publikováno v:
Tetrahedron Letters. 56:3042-3045
A one-pot, three-component reaction between a 2,3-diketoester, an imine, and an aldehyde, catalyzed by p-toluenesulfonic acid, produces fully-substituted 3-aminopyrroles that can be converted to pyrrolo[3,2-d]pyrimidine-2,4-dione.
Publikováno v:
Angewandte Chemie International Edition. 53:6468-6472
Carbonyl–ene reactions of 2,3-diketoesters catalyzed by [Cu{(S,S)-tBu-box}](SbF6)2 [box=bis(oxazoline)] generate chiral α-functionalized α-hydroxy-β-ketoesters in up to 94 % yield and 97 % ee. The 2,3-diketoesters are conveniently accessed from
Autor:
Arthur E. Jacobson, Kenner C. Rice, Yong Sok Lee, Jeffrey R. Deschamps, Sergio A. Hassan, Aaron M. Chadderdon, John R. Traynor, Jonathan L. Katz, Phong M. Truong, Theresa A. Kopajtic
Publikováno v:
Bioorganicmedicinal chemistry. 25(8)
The enantiomers of a variety of N-alkyl-, N-aralkyl-, and N-cyclopropylalkyl-9β-hydroxy-5-(3-hydroxyphenyl)morphans were synthesized employing cyanogen bromide and K2CO3 to improve the original N-demethylation procedure. Their binding affinity to th
Publikováno v:
Organic Letters. 15:3278-3281
Regio- and diastereoselective Lewis acid catalyzed cycloaddition reactions between imines and donor-acceptor cyclopropenes generated from silyl-protected enoldiazoacetates provide direct access to stable cyclopropane-fused tetrahydroquinolines and, w
Publikováno v:
Organic Letters. 14:3608-3611
The intramolecular acid catalyzed aldol cyclization of 2,3,7-triketoesters formed from ζ-keto-α-diazo-β-ketoesters provides highly functionalized cyclopentanones with good diastereoselectivity in high overall yields via kinetically controlled and
Publikováno v:
Tetrahedron Letters. 52:2093-2096
DMDO oxidation of functionalized α-diazo-β-ketoacetates, formed by zinc triflate catalyzed Mukaiyama-aldol condensation of methyl diazoacetoacetate with aldehydes, occurred in quantitative yield to form dihydrofuranols that undergo acid catalyzed d
Publikováno v:
Journal of Heterocyclic Chemistry. 47:1255-1258
Publikováno v:
ChemInform. 46
A one-pot, three-component reaction between a 2,3-diketoester, an imine, and an aldehyde, catalyzed by p-toluenesulfonic acid, produces fully-substituted 3-aminopyrroles that can be converted to pyrrolo[3,2-d]pyrimidine-2,4-dione.
Publikováno v:
ChemInform. 45
Carbonyl–ene reactions of 2,3-diketoesters catalyzed by [Cu{(S,S)-tBu-box}](SbF6)2 [box=bis(oxazoline)] generate chiral α-functionalized α-hydroxy-β-ketoesters in up to 94 % yield and 97 % ee. The 2,3-diketoesters are conveniently accessed from
Publikováno v:
ChemInform. 45
The synthesis of α-carbonylimines by rhodium(II)-catalyzed reactions of α-diazoesters and organic azides is developed and applied in hetero-Diels—Alder reactions to form highly functionalized tetrahydropyrimidines (IX) and in a one-pot, multicomp