Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Phong D Nguyen"'
Autor:
Hessel Honkoop, Dennis EM de Bakker, Alla Aharonov, Fabian Kruse, Avraham Shakked, Phong D Nguyen, Cecilia de Heus, Laurence Garric, Mauro J Muraro, Adam Shoffner, Federico Tessadori, Joshua Craiger Peterson, Wendy Noort, Alberto Bertozzi, Gilbert Weidinger, George Posthuma, Dominic Grün, Willem J van der Laarse, Judith Klumperman, Richard T Jaspers, Kenneth D Poss, Alexander van Oudenaarden, Eldad Tzahor, Jeroen Bakkers
Publikováno v:
eLife, Vol 8 (2019)
While the heart regenerates poorly in mammals, efficient heart regeneration occurs in zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes dedifferentiate and reinitiate proliferation to replace the lost myocar
Externí odkaz:
https://doaj.org/article/88c04f2d61d943049ee30a6c5dc0b5c0
Autor:
Phong D. Nguyen, Iris Gooijers, Giulia Campostrini, Arie O. Verkerk, Hessel Honkoop, Mara Bouwman, Dennis E. M. de Bakker, Tim Koopmans, Aryan Vink, Gerda E. M. Lamers, Avraham Shakked, Jonas Mars, Aat A. Mulder, Sonja Chocron, Kerstin Bartscherer, Eldad Tzahor, Christine L. Mummery, Teun P. de Boer, Milena Bellin, Jeroen Bakkers
Publikováno v:
Science, 380(6646), 758-764. American Association for the Advancement of Science
Zebrafish hearts can regenerate by replacing damaged tissue with new cardiomyocytes. Although the steps leading up to the proliferation of surviving cardiomyocytes have been extensively studied, little is known about the mechanisms that control proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943bee9c72057afcf68114b824ca5b6c
https://doi.org/10.1126/science.abo6718
https://doi.org/10.1126/science.abo6718
Autor:
Yona Goldshmit, Jean Kitty K. Y. Tang, Ashley L. Siegel, Phong D. Nguyen, Jan Kaslin, Peter D. Currie, Patricia R. Jusuf
Publikováno v:
Neural Development, Vol 13, Iss 1, Pp 1-14 (2018)
Abstract Background Despite conserved developmental processes and organization of the vertebrate central nervous system, only some vertebrates including zebrafish can efficiently regenerate neural damage including after spinal cord injury. The mammal
Externí odkaz:
https://doaj.org/article/fbd21fe2995541b3884b3cc6e2f33a1b
Publikováno v:
Cellular and Molecular Life Sciences
Cardiac regeneration is the outcome of the highly regulated interplay of multiple processes, including the inflammatory response, cardiomyocyte dedifferentiation and proliferation, neovascularization and extracellular matrix turnover. Species-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c5e244f89575b3750183203c80f9a2
https://doi.org/10.1007/s00018-021-03831-9
https://doi.org/10.1007/s00018-021-03831-9
Autor:
Carmen Sonntag, Laura A. Galvis, Phong D. Nguyen, Fernando J. Rossello, Jeroen Bakkers, Christophe Marcelle, Kelly L. Rogers, Verena C. Wimmer, Ziad Julier, Abdulsalam I. Isiaku, Thomas Boudier, Mikaël M. Martino, Dhanushika Ratnayake, Silke Berger, Jean Tan, Graham J. Lieschke, A.J. Wood, Peter D. Currie, Viola Oorschot
Publikováno v:
Nature, 591(7849), 281-287. Nature Publishing Group
Skeletal muscle regenerates through the activation of resident stem cells. Termed satellite cells, these normally quiescent cells are induced to proliferate by wound-derived signals1. Identifying the source and nature of these cues has been hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92c8c41215653ede9d65757f855fb20
https://hdl.handle.net/20.500.11755/c22f6e03-989d-4750-a4db-fa3c8c083395
https://hdl.handle.net/20.500.11755/c22f6e03-989d-4750-a4db-fa3c8c083395
Publikováno v:
Geo-Congress 2022.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93a4da185af3fd8515dd4ccb7077d8b
https://doi.org/10.1061/9780784484050.004
https://doi.org/10.1061/9780784484050.004
Autor:
Christian Valdes-Quezada, Sandra S. de Vries, Yuko Sato, Franka J. Rang, Ellen Boele, Kim L. de Luca, Jeroen Bakkers, Jop Kind, Hiroshi Kimura, Phong D. Nguyen, Isabel Guerreiro
Recent advances in single-cell sequencing technologies have enabled simultaneous measurement of multiple cellular modalities, including various combinations of transcriptome, genome and epigenome. However, comprehensive profiling of the histone post-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5507d3f7362950bbd2480e66fc71a944
https://doi.org/10.1101/2021.10.26.465688
https://doi.org/10.1101/2021.10.26.465688
Autor:
Katharina F Sonnen, Phong D. Nguyen, Jeroen Bakkers, Veronique E M van der Velden, Hessel Honkoop
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
Zebrafish are excellent at regenerating their heart by reinitiating proliferation in pre-existing cardiomyocytes. Studying how zebrafish achieve this holds great potential in developing new strategies to boost mammalian heart regeneration. Neverthele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d79113ba8a260be93224618425ad3fe
https://pubmed.ncbi.nlm.nih.gov/34397091
https://pubmed.ncbi.nlm.nih.gov/34397091
Autor:
Alberto Bertozzi, Chi-Chung Wu, Teun P. de Boer, Medhanie A. Mulaw, Charlotte D. Koopman, Jeroen Bakkers, Phong D. Nguyen, Gilbert Weidinger, Mohankrishna Dalvoy Vasudevarao
Adult zebrafish are frequently described to be able to “completely” regenerate the heart. Yet, the extent to which cardiomyocytes lost to injury are replaced is unknown, since only indirect or non-quantitative evidence for cardiomyocyte prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5bc41e4b748f673070aaf82d909ab89
https://doi.org/10.1101/2020.09.08.277939
https://doi.org/10.1101/2020.09.08.277939
Autor:
Thomas Boudier, Mikaël M. Martino, Graham J. Lieschke, Laura A. Galvis, Phong D. Nguyen, Jeroen Bakkers, Abdulsalam I. Isiaku, Verena C. Wimmer, Kelly L. Rogers, Christophe Marcelle, Fernando J. Rossello, Ziad Julier, Dhanushika Ratnayake, A.J. Wood, Viola Oorschot, Peter D. Currie
Skeletal muscle is paradigmatic of a regenerative tissue that repairs itself via the activation of a resident stem cell1. Termed the satellite cell, these normally quiescent cells are induced to proliferate by ill-defined wound-derived signals2. Iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54e5e29da48a1071da4e3af1f36b9725
https://doi.org/10.1101/2020.08.24.262428
https://doi.org/10.1101/2020.08.24.262428