Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Phoebus Rosakis"'
Autor:
Chrysovalantou Kalaitzidou, Georgios Grekas, Andreas Zilian, Charalambos Makridakis, Phoebus Rosakis
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 7, p e1012238 (2024)
We present a new model and extensive computations that explain the dramatic remodelling undergone by a fibrous collagen extracellular matrix (ECM), when subjected to contractile mechanical forces from embedded cells or cell clusters. This remodelling
Externí odkaz:
https://doaj.org/article/41e458ca175947e9aca6fe76483e6eef
Publikováno v:
Surface Science. 732:122265
We present data-driven simulations for gold nanostructures, and develop a model that links total energy to geometrical features of the particle, with the ultimate goal of deriving reliable edge energies of gold. Assuming that the total energy can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb32a80cea6144c6355f5d25c3f41a36
https://doi.org/10.1016/j.susc.2023.122265
https://doi.org/10.1016/j.susc.2023.122265
Autor:
Chrysovalantou Kalaitzidou, Georgios Grekas, Andreas Zilian, Charalambos Makridakis, Phoebus Rosakis
Publikováno v:
Web of Science
Through modelling and simulations we show that material instabilities play a dominant role in the mechanical behavior of the fibrous collagen Extracellular Matrix (ECM), as observed when the ECM is deformed by contractile biological cells. We compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489bf17e17fb35730fc63362afdd03e0
Autor:
Maria E. Marketou, Phoebus Rosakis
Publikováno v:
Journal of Infection
The Journal of Infection
The Journal of Infection
The case fatality ratio (CFR) for COVID-19 is difficult to estimate. One difficulty is due to ignoring or overestimating time delay between reporting and death. We claim that all of these cause large errors and artificial time dependence of the CFR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07398333849e158bea5a99df55c7717
https://doi.org/10.1016/j.jinf.2020.06.010
https://doi.org/10.1016/j.jinf.2020.06.010
A mathematical model is proposed for shape evolution and locomotion of fish epidermal keratocytes on elastic substrates. The model is based on mechanosensing concepts: cells apply contractile forces onto the elastic substrate, while cell shape evolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053578bcf9ffa0590033313d1e8b4770
A mathematical model is proposed for shape evolution and locomotion of fish epidermal keratocytes on elastic substrates. The model is based on mechanosensing concepts: cells apply contractile forces onto the elastic substrate, while cell shape evolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a506a03c170d39ce1533b595150c734
We consider a model of energy minimization arising in the study of the mechanical behavior caused by cell contraction within a fibrous biological medium. The macroscopic model is based on the theory of non rank-one convex nonlinear elasticity for pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f485b257011b04fab4bc4d1338610a6
http://arxiv.org/abs/1907.01382
http://arxiv.org/abs/1907.01382
Autor:
Charalambos Makridakis, Phoebus Rosakis, Maria Proestaki, Guruswami Ravichandran, Georgios Grekas, Jacob Notbohm
Publikováno v:
Journal of The Royal Society Interface
J R Soc Interface
J R Soc Interface
Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers—tracts of high densification and fibre alignment—form between cells, thinner bands emanate from cell clusters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe59b4df3fb729647c0f133e0a0b752
http://arxiv.org/abs/1905.11246
http://arxiv.org/abs/1905.11246
Publikováno v:
Journal of the Mechanics and Physics of Solids
We propose a one-dimensional, nonconvex elastic constitutive model with higher gradients that can predict spontaneous fracture at a critical load via a bifurcation analysis. It overcomes the problem of discontinuous deformations without additional fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f64c0650c7c179a7bdd75fcf2fbf2e2
https://doi.org/10.1016/j.jmps.2021.104352
https://doi.org/10.1016/j.jmps.2021.104352
Publikováno v:
J R Soc Interface
A mathematical model is proposed for shape evolution and locomotion of fish epidermal keratocytes on elastic substrates. The model is based on mechanosensing concepts: cells apply contractile forces onto the elastic substrate, while cell shape evolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66989250d010159f4d07188e36682e25
https://doi.org/10.1098/rsif.2020.0175
https://doi.org/10.1098/rsif.2020.0175