Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Phoebe Dewing"'
Publikováno v:
Journal of Neuroscience Research. 93:67-74
Sensory feedback is an important component of any behavior, with each instance influencing subsequent activity. Female sexual receptivity is mediated both by the steroid hormone milieu and interaction with the male. We tested the influence of repeate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dcf0a73a6fdd4662f1b46824fe5f52e
https://doi.org/10.1002/jnr.23463
https://doi.org/10.1002/jnr.23463
Publikováno v:
Steroids. 78:607-613
Regulation of sexual reproduction by estradiol involves the activation of estrogen receptors (ERs) in the hypothalamus. Of the two classical ERs involved in reproduction, ERα appears to be the critical isoform. The role of ERα in reproduction has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a66852e835b8bfd4b658497b7496330
https://doi.org/10.1016/j.steroids.2012.12.008
https://doi.org/10.1016/j.steroids.2012.12.008
Publikováno v:
The Journal of Neuroscience. 31:17583-17589
Estrogens have profound actions on the structure of the nervous system during development and in adulthood. One of the signature actions of estradiol is to alter the morphology of neural processes. In the hippocampus, estradiol modulates spines and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0c66d92c5cbdd6af4be30b0b68763c
https://doi.org/10.1523/jneurosci.3030-11.2011
https://doi.org/10.1523/jneurosci.3030-11.2011
Publikováno v:
Endocrinology. 149:5934-5942
Rapid membrane-mediated estradiol signaling regulating sexual receptivity requires the interaction of the estrogen receptor (ER)- and the metabotropic glutamate receptor 1a (mGluR1a). A cell signaling antibody microarray revealed that estradiol activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f466d89eff97b898d17c1f5d03ee3a04
https://doi.org/10.1210/en.2008-0847
https://doi.org/10.1210/en.2008-0847
Autor:
Phoebe Dewing, Amy Christensen, Paul E. Micevych, Paul G. Mermelstein, Marissa I. Boulware, Kevin Sinchak
Publikováno v:
The Journal of Neuroscience. 27:9294-9300
In rats, female sexual behavior is regulated by a well defined limbic–hypothalamic circuit that integrates sensory and hormonal information. Estradiol activation of this circuit results in μ-opioid receptor (MOR) internalization in the medial preo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e02b3a51a704fd7c2749daa550f4941
https://doi.org/10.1523/jneurosci.0592-07.2007
https://doi.org/10.1523/jneurosci.0592-07.2007
Autor:
Paul E. Micevych, Sabine Kelly, Eric Vilain, Pierre-Olivier Fernagut, Charleston W. K. Chiang, Kenneth H. Albrecht, Kevin Sinchak, Phoebe Dewing, Marie-Françoise Chesselet, Vincent R. Harley, Helena Sim
Publikováno v:
Current Biology. 16:415-420
SummaryThe central dogma of mammalian brain sexual differentiation has contended that sex steroids of gonadal origin organize the neural circuits of the developing brain [1]. Recent evidence has begun to challenge this idea and has suggested that, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1564c4ed8cd72efbb9fe51eeb3dbf5ec
https://doi.org/10.1016/j.cub.2006.01.017
https://doi.org/10.1016/j.cub.2006.01.017
Publikováno v:
Molecular Brain Research. 118:82-90
The classic view of brain sexual differentiation and behavior is that gonadal steroid hormones act directly to promote sex differences in neural and behavioral development. In particular, the actions of testosterone and its metabolites induce a mascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b916f6c043c596cd03d4c0d58312a13
https://doi.org/10.1016/s0169-328x(03)00339-5
https://doi.org/10.1016/s0169-328x(03)00339-5
Autor:
Max Berger, Amy Christensen, Kevin Sinchak, Paul E. Micevych, Laura Ponce, Liliana Gomez, Phoebe Dewing
Publikováno v:
Hormones and behavior. 64(1)
Estradiol rapidly activates a microcircuit in the arcuate nucleus of the hypothalamus (ARH) that is needed for maximal female sexual receptivity. Membrane estrogen receptor-α complexes with and signals through the metabotropic glutamate receptor-1a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fddfe7bd33f10b03fee8c937616d469
https://pubmed.ncbi.nlm.nih.gov/23756153
https://pubmed.ncbi.nlm.nih.gov/23756153
Autor:
Phoebe Dewing, Paul E. Micevych
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 2 (2011)
Frontiers in endocrinology, vol 2, iss SEP
Frontiers in Endocrinology, Vol 2 (2011)
Frontiers in endocrinology, vol 2, iss SEP
Estradiol has profound actions on the structure and function of the nervous system. In addition to nuclear actions that directly modulate gene expression, the idea that estradiol can rapidly activate cell signaling by binding to membrane estrogen rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a59f9f2c7a80ccb95945577de9054b
Publikováno v:
Endocrinology. 148(2)
The brain synthesizes steroids de novo, especially progesterone. Recently estradiol has been shown to stimulate progesterone synthesis in the hypothalamus and enriched astrocyte cultures derived from neonatal cortex. Estradiol-induced hypothalamic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c16ee957bf677ac3a42197b05df7ace
https://pubmed.ncbi.nlm.nih.gov/17095591
https://pubmed.ncbi.nlm.nih.gov/17095591