Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Phoebe Cao"'
Autor:
Emily L. Giddings, Devin P. Champagne, Meng-Han Wu, Joshua M. Laffin, Tina M. Thornton, Felipe Valenca-Pereira, Rachel Culp-Hill, Karen A. Fortner, Natalia Romero, James East, Phoebe Cao, Hugo Arias-Pulido, Karatatiwant S. Sidhu, Brian Silverstrim, Yoonseok Kam, Shana Kelley, Mark Pereira, Susan E. Bates, Janice Y. Bunn, Steven N. Fiering, Dwight E. Matthews, Robert W. Robey, Domink Stich, Angelo D’Alessandro, Mercedes Rincon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug efflux through ABC transporters is a common mechanism leading to chemoresistance in cancer. Here, the authors show that mitochondrial respiration provides ATP to allow ABC transporters activity so mitochondrial respiration inhibition overcomes c
Externí odkaz:
https://doaj.org/article/96cc5e262fc1481b86eceff834f1a9ce
Publikováno v:
The Journal of Immunology. 208:118.15-118.15
The gamma common chain (γc) cytokine receptor plays a central role in Type I cytokine signaling, and in the generation and expansion of antitumor T-cells. Adoptive T-cell therapies (ACT) benefit from IL-2 treatment but is limited by a short half-lif
Autor:
Devin P. Champagne, Karatatiwant Singh Sidhu, Robert W. Robey, Angelo D'Alessandro, Janice Y. Bunn, Susan E. Bates, Brian Silverstrim, Tina M. Thornton, Steven Fiering, Joshua M. Laffin, Karen A. Fortner, Dwight E. Matthews, Hugo Arias-Pulido, Felipe Valença-Pereira, Natalia Romero, Mercedes Rincon, Shana O. Kelley, Mark P. Pereira, Phoebe Cao, Domink Stich, Emily Giddings, Meng Han Wu, Yoonseok Kam, James East, Rachel Culp-Hill
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem. The development of safe and