Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Phimmada Hatthakarnkul"'
Autor:
Norman J. Galbraith, Jean A. Quinn, Sara Sf Al-Badran, Kathryn A.F. Pennel, Lily V.S. Hillson, Phimmada Hatthakarnkul, Molly McKenzie, Noori Maka, Lynette Loi, Mikaela Frixou, Colin W. Steele, Campbell S. Roxburgh, Paul G. Horgan, Donald C. McMillan, Joanne Edwards
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102064- (2024)
Background: Transforming growth factor β-activated protein kinase-1 (TAK1) plays an important role in MAPK and NFκB pathways and has been associated with colorectal cancer. The aim of this study was to determine how cytoplasmic and juxtanuclear pun
Externí odkaz:
https://doaj.org/article/f77b384652bb4325a5076d3ce2c361b8
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Autor:
Phimmada Hatthakarnkul, Kathryn Pennel, Peter Alexander, Hester vanWyk, Antonia Roseweir, Jitwadee Inthagard, Jennifer Hay, Ditte Andersen, Noori Maka, James Park, Campbell Roxburgh, Chanitra Thuwajit, Donald McMillan, Joanne Edwards
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy and research is focused on identifying novel ways to subtype patients. In this study, a novel classification system, tumour microenvironment score (TMS), was devised based on Klintrup–M
Externí odkaz:
https://doaj.org/article/7cd476cd4b6e49e793cf072a26acb064
Autor:
Elizabeth Morrow, Kathryn Pennel, Phimmada Hatthakarnkul, Holly Leslie, Elizabeth Mallon, Ditte Andersen, Nigel Jamieson, Donald McMillan, Antonia Roseweir, Joanne Edwards
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13225-13240 (2023)
Abstract Introduction Triple‐negative breast cancer (TNBC) patients have the poorest clinical outcomes compared to other molecular subtypes of breast cancer. IL6/JAK/STAT3 signalling is upregulated in breast cancer; however, there is limited eviden
Externí odkaz:
https://doaj.org/article/b7f8d046e38e4a45a5c1b03fb306d1a4
Autor:
Elizabeth Morrow, Kathryn Pennel, Phimmada Hatthakarnkul, Holly Leslie, Elizabeth Mallon, Ditte Andersen, Nigel Jamieson, Donald McMillan, Antonia Roseweir, Joanne Edwards
Publikováno v:
Cancer Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b4944bb420f915f1c3e85059424c80
https://doi.org/10.1002/cam4.6014
https://doi.org/10.1002/cam4.6014
Autor:
Supaporn Yangngam, Jaturawitt Prasopsiri, Phimmada Hatthakarnkul, Suyanee Thongchot, Peti Thuwajit, Pa-thai Yenchitsomanus, Joanne Edwards, Chanitra Thuwajit
Nucleolin (NCL) is a multifunctional protein expressed in the nucleus, cytoplasm, and cell membrane. Overexpression of NCL has a controversial role as a poor prognostic marker in cancers. In this study, a meta-analysis was performed to evaluate the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372dab9b60b1cb7594999caeac284ea3
https://eprints.gla.ac.uk/275943/1/275943.pdf
https://eprints.gla.ac.uk/275943/1/275943.pdf
Autor:
Lily V. Hillson, Ross K. McMahon, Kathryn A. Pennel, Jean A. Quinn, Leia Jones, Raheleh Amirkhah, Aula Ammar, Phimmada Hatthakarnkul, Annabelle Ferguson, Simon W. Milling, Alec McDonald, Philip D. Dunne, Joanne Edwards, Sean M. O'Cathail, Campbell S. Roxburgh
Publikováno v:
Cancer Research. 83:3231-3231
Background. Two pre-operative radiotherapy (RT) regimens are in common use for patients (pts) with locally advanced rectal cancer (LARC): Conventionally fractionated, long course chemoradiation (LCCRT, 25x1.8Gy with concomitant chemotherapy) or hypof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c38a3135307b0902a62bf8b1c6ae79
https://doi.org/10.1158/1538-7445.am2023-3231
https://doi.org/10.1158/1538-7445.am2023-3231
Autor:
Colin Wood, Phimmada Hatthakarnkul, Holly Leslie, Assya Legrini, Andrew Cameron, Kathryn AF Pennel, Owen J Sansom, Joanne Edwards, Nigel Balfour Jamieson, Colin William Steele
Publikováno v:
Journal of Clinical Oncology. 41:251-251
251 Background: Colorectal Cancer (CRC) remains a significant healthcare problem. Interest in the role of the Tumour Microenvironment (TME) in progression and metastasis is established, yet much remains to be learned about the mechanism of immune cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128be015cd74a1c9c9be29fcea9b1d28
https://doi.org/10.1200/jco.2023.41.4_suppl.251
https://doi.org/10.1200/jco.2023.41.4_suppl.251
Autor:
Norman James Galbraith, Sara SF Al-Badran, Phimmada Hatthakarnkul, Kathryn AF Pennel, Jean A. Quinn, Lynette Loi, Noori Maka, Colin William Steele, Campbell SD Roxburgh, Donald C. McMillan, Paul G. Horgan, Joanne Edwards
Publikováno v:
Journal of Clinical Oncology. 41:220-220
220 Background: Microsatellite stable (MSS) colorectal cancer continues to have limited options for personalised therapeutic targets. The NFKB pathway is known to play an important role in inflammation-related carcinogenesis but has yet to be transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cda51fdb1e67d97f712afda063d1c1
https://doi.org/10.1200/jco.2023.41.4_suppl.220
https://doi.org/10.1200/jco.2023.41.4_suppl.220
Autor:
Hester C. van Wyk, Phimmada Hatthakarnkul, Amna Ahmed Mohemmd Matly, Aula Ammar, Donald C. McMillan, Joanne Edwards, Jean A. Quinn
Publikováno v:
Critical reviews in oncology/hematology. 167
Introduction:\ud Despite a well-known prognostic role in colorectal cancer, the genomic profiling of tumour budding remains to be elucidated. We aim to review the association of common mutations with tumour budding.\ud \ud Methods:\ud A systematic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cbc8f168c50e90de9eee7eec0dc4ab
https://pubmed.ncbi.nlm.nih.gov/34619332
https://pubmed.ncbi.nlm.nih.gov/34619332