Association between synovial tissue damage and pain in late-stage knee osteoarthritis: A cross-sectional study.

Autor: Philpott HT; Faculty of Health Sciences, University of Western Ontario, London, ON N6G 1H1, Canada,; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada., Birmingham TB; Faculty of Health Sciences, University of Western Ontario, London, ON N6G 1H1, Canada,; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada., Carter MM; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada; Physiology & Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Cecchini MJ; Pathology & Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Giffin JR; Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Vasarhelyi EM; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada; Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., MacDonald SJ; Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Lanting BA; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada; Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Appleton CT; Bone and Joint Institute, University of Western Ontario, London Health Sciences Centre-University Hospital, London, ON N6A 5B5, Canada; Physiology & Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada. Electronic address: tom.appleton@sjhc.london.on.ca.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2024 Nov; Vol. 32 (11), pp. 1503-1512. Date of Electronic Publication: 2024 Jul 04.

Changes and associations between synovial fluid and magnetic resonance imaging markers of osteoarthritis after high tibial osteotomy.

Autor: Schulz JM; School of Physical Therapy, Faculty of Health Sciences, Western University, London, ON, Canada. jschulz2@uwo.ca.; Bone and Joint Institute, Western University, London, ON, Canada. jschulz2@uwo.ca.; Fowler Kennedy Sport Medicine Clinic, Western University, London, ON, Canada. jschulz2@uwo.ca., Birmingham TB; School of Physical Therapy, Faculty of Health Sciences, Western University, London, ON, Canada.; Bone and Joint Institute, Western University, London, ON, Canada.; Fowler Kennedy Sport Medicine Clinic, Western University, London, ON, Canada., Philpott HT; Bone and Joint Institute, Western University, London, ON, Canada.; Department of Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada., Appleton CT; Bone and Joint Institute, Western University, London, ON, Canada.; Department of Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada., Atkinson HF; Bone and Joint Institute, Western University, London, ON, Canada.; Department of Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada., Giffin JR; Bone and Joint Institute, Western University, London, ON, Canada.; Fowler Kennedy Sport Medicine Clinic, Western University, London, ON, Canada.; Department of Surgery, Schulich School of Medicine, Western University, London, ON, Canada., Beier F; Bone and Joint Institute, Western University, London, ON, Canada.; Department of Physiology & Pharmacology, Schulich School of Medicine, Western University, London, ON, Canada.

Publikováno v: Arthritis research & therapy [Arthritis Res Ther] 2024 Oct 10; Vol. 26 (1), pp. 176. Date of Electronic Publication: 2024 Oct 10.

Effects of risk factors on evoked pain patterns in rat models of experimental knee osteoarthritis.

Autor: Philpott HT; Faculty of Health Sciences, Western University, London, Ontario, Canada.; Bone and Joint Institute, Western University, London, Ontario, Canada., Blackler G; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Daniel Klapak J; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Pitchers KK; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Tomlinson M; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Smith N; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Viehweger J; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Umoh JU; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Preclinical Imaging Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada., Holdsworth DW; Bone and Joint Institute, Western University, London, Ontario, Canada.; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Preclinical Imaging Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada., Maerz T; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA., Thomas Appleton C; Bone and Joint Institute, Western University, London, Ontario, Canada.; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Publikováno v: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2023 Dec; Vol. 41 (12), pp. 2617-2628. Date of Electronic Publication: 2023 May 11.

Changes and Associations Between Gait Biomechanics and Knee Inflammation After Aspiration and Glucocorticoid Injection for Knee Osteoarthritis.

Autor: Pinto RF; University of Western Ontario and London Health Sciences Centre-University Hospital, London, Ontario, Canada., Birmingham TB; University of Western Ontario and London Health Sciences Centre-University Hospital, London, Ontario, Canada., Philpott HT; University of Western Ontario and London Health Sciences Centre-University Hospital, London, Ontario, Canada., Primeau CA; University of Western Ontario and London Health Sciences Centre-University Hospital, London, Ontario, Canada., Leitch KM; University of Western Ontario and London Health Sciences Centre-University Hospital, London, Ontario, Canada., Arsenault DA; University of Western Ontario, London, Ontario, Canada., Appleton CT; St. Joseph's Health Care London and Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

Publikováno v: Arthritis care & research [Arthritis Care Res (Hoboken)] 2023 Aug; Vol. 75 (8), pp. 1764-1772. Date of Electronic Publication: 2023 Feb 06.

Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis.

Autor: Del Sordo L; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, and Western Bone and Joint Institute, The University of Western Ontario, London, Canada., Blackler GB; Department of Physiology and Pharmacology, and Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada., Philpott HT; Faculty of Health Sciences, and Western Bone and Joint Institute, The University of Western Ontario, London, Canada., Riviere J; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada., Gunaratnam L; Department of Medicine and Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada., Heit B; Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada., Appleton CT; Department of Physiology and Pharmacology and Department of Medicine, Schulich School of Medicine and Dentistry, and Western Bone and Joint Institute, The University of Western Ontario, London, Canada.

Publikováno v: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2023 May; Vol. 75 (5), pp. 685-696. Date of Electronic Publication: 2023 Mar 07.