Zobrazeno 1 - 10
of 11 489
pro vyhledávání: '"Philpott A"'
We present a capacity expansion model for deciding the new electricity generation and transmission capacity to complement an existing hydroelectric reservoir system. The objective is to meet a forecast demand at least expected cost, namely the capita
Externí odkaz:
http://arxiv.org/abs/2312.08556
Autor:
Jenna M. Schulz, Trevor B. Birmingham, Holly T. Philpott, C. Thomas Appleton, Hayden F. Atkinson, J. Robert Giffin, Frank Beier
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Mechanobiological mechanisms of osteoarthritis (OA) are unclear. Our objectives were to explore: 1) changes in knee joint physiology using a large panel of synovial fluid biomarkers from before to one year after high tibial osteot
Externí odkaz:
https://doaj.org/article/8c23195c0cdf4b74b9cc97da6115444d
Autor:
Charlotte Lovatt, Megan Williams, Alex Gibbs, Abdullahi Mukhtar, Huw J. Morgan, Simone Lanfredini, Carlotta Olivero, Gill Spurlock, Sally Davies, Charlotte Philpott, Hannah Tovell, Peter Turnpenny, Dilair Baban, Sam Knight, Hilde Brems, Julian R. Sampson, Eric Legius, Meena Upadhyaya, Girish K. Patel
Publikováno v:
Skin Health and Disease, Vol 4, Iss 5, Pp n/a-n/a (2024)
Abstract Background RASopathies, which include neurofibromatosis type 1 (NF1), are defined by Ras/mitogen‐activated protein kinase (Ras/MAPK) pathway activation. They represent a group of clinically related disorders often characterised by multiple
Externí odkaz:
https://doaj.org/article/29da299745d74d36ac871e53f319e90b
Autor:
Amy Grant, Rachel Giacomantonio, Kelly Lackie, Adrian MacKenzie, Elizabeth Jeffers, Julia Kontak, Emily Gard Marshall, Susan Philpott, Debbie Sheppard-LeMoine, Elizabeth Lappin, Alice Bruce, Amy Mireault, Deanna Beck, Lindsay Cormier, Ruth Martin-Misener
Publikováno v:
BMC Primary Care, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Interprofessional primary care teams (IPCTs) work together to enhance care. Despite evidence on the benefits of IPCTs, implementation remains challenging. This research aims to 1) identify and prioritize barriers and enablers, and
Externí odkaz:
https://doaj.org/article/901e376d8ab541fcb0898bc1d25c5396
Publikováno v:
Harm Reduction Journal, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background As well as being associated with serious negative health outcomes, smoking has been reported to have an array of physiological and psychological effects, including effects on mood and cognitive function. Post-cessation, loss of su
Externí odkaz:
https://doaj.org/article/b2275683f3b04b6a9c5b5eea4bde0b19
Autor:
Paul Y. Bi, Samuel A. Killackey, Linus Schweizer, Damien Arnoult, Dana J. Philpott, Stephen E. Girardin
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Mitochondrial stress inducers such as carbonyl cyanide m-chlorophenyl hydrazone (CCCP) and oligomycin trigger the DELE1-HRI branch of the integrated stress response (ISR) pathway. Previous studies performed using epitope-tagged DELE1 showed
Externí odkaz:
https://doaj.org/article/2c938dc33b884251b8cbcb518cef007c
Autor:
Garth Blackler, Yue Lai-Zhao, Joseph Klapak, Holly T. Philpott, Kyle K. Pitchers, Andrew R. Maher, Benoit Fiset, Logan A. Walsh, Elizabeth R. Gillies, C. Thomas Appleton
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Pain from osteoarthritis (OA) is one of the top causes of disability worldwide, but effective treatment is lacking. Nociceptive factors are released by activated synovial macrophages in OA, but depletion of synovial macrophages pa
Externí odkaz:
https://doaj.org/article/0940f57f8f3a45eebcbb4ee9caf19d39
Autor:
Anne Philpott, Paromita Vohra
Publikováno v:
Sexual and Reproductive Health Matters, Vol 32, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/d6d68246c1fe46a780149544c8f0b778
Autor:
Amjad Sawah MD, MChOrth, Sarang Kasture FRCS(Tr&Orth), Alastair Bond PhD, Lauren Fisher PhD, Andrew Fisher PhD, Matthew Philpott FRCS(Tr&Orth), Lyndon Mason FRCS(Tr&Orth), Andy Molloy FRCS(Tr&Orth)
Publikováno v:
Foot & Ankle Orthopaedics, Vol 9 (2024)
Background: The spring ligament fibrocartilaginous complex (SLFC), which is essential for stabilizing the medial longitudinal arch, features a little-explored fibrocartilaginous facet within its superomedial aspect, articulating with the talar head.
Externí odkaz:
https://doaj.org/article/67465c95a7164446b160eba0e2d040b2
Autor:
Revathy Ramachandran, Shakhzada Ibragimova, Laura M. Woods, Tamader AlHouqani, Roshna Lawrence Gomez, Fabrizio Simeoni, Mahmood Y. Hachim, Tim C.P. Somervaille, Anna Philpott, Jason S. Carroll, Fahad R. Ali
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110500- (2024)
Summary: Triple-negative breast cancer (TNBC) is characterized by lack of the estrogen (ER) receptor, progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2), and standard receptor-targeted therapies are ineffective. FOXC1, a
Externí odkaz:
https://doaj.org/article/95f276360fa1442aa803bad570a00ca8