Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Philomena O'Byrne"'
Autor:
Jason A. Roberts, Philomena O'Byrne, Johnny McHugh, Jérôme P. Fennell, Brett McWhinney, Deirdre M. D’Arcy, Evelyn Deasy, Sheila A. Ryder, Catherine J. Byrne, Ted Parton, Sean Egan, Helen Enright, Ronan Desmond
Publikováno v:
The Journal of antimicrobial chemotherapy. 73(4)
To develop a pharmacokinetic model describing total and unbound teicoplanin concentrations in patients with haematological malignancy and to perform Monte Carlo simulations to evaluate target attainment of unbound trough concentrations with various d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271a2b4900456782616796edf36ec6e7
https://pubmed.ncbi.nlm.nih.gov/29272419
https://pubmed.ncbi.nlm.nih.gov/29272419
Autor:
Sean Egan, Deirdre M. D’Arcy, Evelyn Deasy, Helen Enright, Sheila A. Ryder, Jérôme P. Fennell, Johnny McHugh, Philomena O'Byrne, Catherine J. Byrne
Publikováno v:
European Journal of Hospital Pharmacy. 21:301-305
Objective To investigate current practices with teicoplanin in patients with haematological malignancy in centres throughout the UK and Ireland with respect to indication for usage and timing of introduction in febrile neutropenia, dosage regimens an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::335e4721871404a1c163dd0b253fd90c
https://doi.org/10.1136/ejhpharm-2013-000412
https://doi.org/10.1136/ejhpharm-2013-000412
Autor:
Sheila A. Ryder, Brett McWhinney, Philomena O'Byrne, Jason A. Roberts, Evelyn Deasy, Sean Egan, Jérôme P. Fennell, Helen Enright, Johnny McHugh, Ronan Desmond, Catherine J. Byrne, Deirdre M. D’Arcy
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 23(9)
Objectives To describe the population pharmacokinetics of teicoplanin in adult patients with haematological malignancies receiving higher than standard doses, and to perform Monte Carlo simulations to determine dosing regimens associated with optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dec2bda9e2af34ddaa5baaf25c92e38
https://pubmed.ncbi.nlm.nih.gov/28267636
https://pubmed.ncbi.nlm.nih.gov/28267636
Autor:
Catherine J. Byrne, Evelyn Deasy, Philomena O'Byrne, Jason A. Roberts, Sheila A. Ryder, Johnny McHugh, Brett McWhinney, Deirdre M. D’Arcy, Jérôme P. Fennell, Ronan Desmond, Sean Egan, Helen Enright
Publikováno v:
Antimicrobial agents and chemotherapy. 61(6)
The objective of this study was to explore the following aspects of teicoplanin use in patients with hematological malignancy: early attainment of target trough concentrations with current high-dose teicoplanin regimens, variability in unbound teicop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e188233769dd3a72df89c6bde04895
https://pubmed.ncbi.nlm.nih.gov/28320714
https://pubmed.ncbi.nlm.nih.gov/28320714
Autor:
Evelyn Deasy, Deirdre M. D’Arcy, Sheila A. Ryder, Johnny McHugh, Jérôme P. Fennell, Philomena O'Byrne, Sean Egan, Helen Enright, Catherine J. Byrne
Publikováno v:
International journal of antimicrobial agents. 46(4)
In 2010, our hospital introduced a higher target teicoplanin trough concentration of ≥20 mg/L by Day 3 for haematological malignancy patients. This study aimed to explore whether target trough concentrations were achieved, to identify factors assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a586b7444eaf7f8f0b955a732c15e22f
https://pubmed.ncbi.nlm.nih.gov/26228465
https://pubmed.ncbi.nlm.nih.gov/26228465
Autor:
Michael Jeffers, John O'Loughlin, Niamh Strahan, Sarah O'Dowd, Ronan Desmond, Su Wai Maung, Johnny McHugh, Helen Enright, Philomena O'Byrne
Publikováno v:
Blood. 126:2878-2878
Introduction The TP53 gene encodes the tumour suppressor and cell cycle regulatory protein and is found to be mutated in a variety of carcinomas. Mutation in TP53 gene is associated with resistance to conventional therapy, disease progression and ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16cfb2f4c400e74d42daee77f71ed7f
https://doi.org/10.1182/blood.v126.23.2878.2878
https://doi.org/10.1182/blood.v126.23.2878.2878