Novel strategies for the treatment of acute pancreatitis based on the determinants of severity.

Autor: Windsor, John A, Escott, Alistair, Brown, Lisa, Phillips, Anthony RJ

Publikováno v: Journal of Gastroenterology & Hepatology; Nov2017, Vol. 32 Issue 11, p1796-1803, 8p, 3 Diagrams, 2 Charts, 1 Graph

High-fat feeding drives the intestinal production and assembly of C 16:0 ceramides in chylomicrons.

Autor: Mah MS; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Cao E; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Anderson D; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Escott A; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.; HBP/Upper GI Unit, Department of General Surgery, Auckland City Hospital, Auckland, New Zealand., Tegegne S; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Gracia G; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Schmitz J; Max Planck Institute for Metabolism and Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), Cologne, Germany., Brodesser S; University of Cologne, Faculty of Medicine and University Hospital of Cologne, Cluster of Excellence Cellular Stress Responses in Aging associated Diseases (CECAD), Cologne, Germany., Zaph C; Biomedical Discovery Institute, Monash University, Melbourne, Australia., Creek DJ; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Hong J; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.; Applied Surgery and Metabolism Laboratory, School of Biological Sciences, The University of Auckland, Auckland, New Zealand., Windsor JA; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.; HBP/Upper GI Unit, Department of General Surgery, Auckland City Hospital, Auckland, New Zealand., Phillips AR; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.; Applied Surgery and Metabolism Laboratory, School of Biological Sciences, The University of Auckland, Auckland, New Zealand., Trevaskis NL; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Febbraio MA; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia., Turpin-Nolan SM; Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia.

Publikováno v: Science advances [Sci Adv] 2024 Aug 23; Vol. 10 (34), pp. eadp2254. Date of Electronic Publication: 2024 Aug 23.